Frequency and prognostic significance of epithelioid cell reactions and microcarcinosis in the regional lymph nodes in the presence of gastric carcinoma;Haufigkeit und prognostische Bedeutung von epitheloidzelligen Reaktionen und Mikrokarzinosen in den regionaren Lymphknoten beim Magenkarzinom

Pathologe

Volumn 18, Issue 2, 1997, Pages 124-130

  Kestlmeier, R ^a   Busch, Raymonde ^a   Fellbaum, Ch ^a,c   Boettcher, K ^a   Reich, Ulrike ^b   Siewert, J R ^a   Hofler H ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

epithelioid cell reaction; gastric carcinoma; lymph nodes; metastasis; microcarcinosis; prognosis; single tumor cells

Indexed keywords

ADULT; AGED; ARTICLE; GRANULOMA; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PROGNOSIS; STOMACH CARCINOMA; ADENOCARCINOMA; CANCER STAGING; ENZYME IMMUNOASSAY; EPITHELIUM; LYMPH NODE; LYMPHADENECTOMY; METASTASIS; PATHOLOGY; SPLEEN; SPLEEN TUMOR; STOMACH;

TUMOR MARKER;

ADENOCARCINOMA; EPITHELIUM; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; NEOPLASM STAGING; PROGNOSIS; SPLEEN; SPLENIC NEOPLASMS; STOMACH; TUMOR MARKERS, BIOLOGICAL;

EID: 0030927230     PISSN: 01728113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002920050200     Document Type: Article

References (30)

1. Becker HD (1991) Radikalitätsprinzipien beim Magencarcinom: eine kritische Betrachtung. Chirurg 62: 878-880
2. Becker KF, Atkinson MJ, Reich U, Becker I, Huang HH, Nekarda H, Siewert JR, Höfler H (1994) E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res 54: 3845-3852
3. Böttcher K, Becker K, Busch R, Roder JD, Siewert JR (1992) Prognosefaktoren beim Magencarcinom. Ergebnisse einer uni- und multivariaten Analyse. Chirurg 63: 656-661
4. Brooks JSJ, Livolsi VA, Pietra GG (1990) Mesothelial cell inclusions in mediastinal lymph nodes mimicking metastatic carcinoma. Am J Clin Pathol 93: 741-748
5. Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, Pulford KAF, Stein H, Mason DJ (1984) Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (AP-AAP complexes). J Histochem Cytochem 32: 219-229
6. Cox DR (1972) Regression models and life-tables. J R Stat Soc [B] 34: 187-220
7. Gabbert HE, Meier S, Gerharz DG, Hommel G (1992) Tumor-cell dissociation at the invasion front: a new prognostic parameter in gastric cancer patients. Int J Cancer 50: 202-207
8. Greenson JK, Isenhart CE, Rice R, Mojzisik C, Houchens D, Martin EW (1994) Identification of occult micrometastases in pericolic lymph nodes of Dukes' B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49: correlation with long-term survival. Cancer 73: 563-569
9. Herxheimer G (1917) Über Karzinom und Tuberkulose. Z Tuberk 27: 251-258
10. Jeffers MD, O'Dowd GM, Mulcahy H, Stagg M, O'Donoghue DP, Toner M (1994) The prognostic significance of immunohistochemically detected lymph node micrometastases in colorectal carcinoma. J Pathol 172: 183-187
11. Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. Am Statist Assoc J 53: 457-481
12. Knolle J (1988) Immunohistochemische Charakterisierung von Epitheloidzellen. Acta Histochem [Suppl] 35: 159-164
13. Korenaga D, Haraguchi M, Okamura T, Baba H, Saito A, Sugimachi K (1989) DNA ploidy and tumor invasion in human gastric cancer: histopathologic differentiation. Arch Surg 124: 314-318
14. Latza U, Niedobitek G, Schwarting R, Nekarda H, Stein H (1990) Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelia. J Clin Pathol 43: 213-219
15. Laurén P (1965) The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. Acta Pathol Microbiol Scand 64: 31-49
16. Mascarel I de, Bonichon F, Coindre JM, Trojani M (1992) Prognostic significance of breast cancer axillery lymph node micrometastases assessed by two special techniques: reevaluation with longer follow-up. Br J Cancer 66: 523-527
17. Miles WE (1910) The radical abdominoperineal operation for cancer of the rectum and the pelvic colon. Br Med J 2: 941-943
18. Nasser IA, Lee AKC, Bosari S, Saganich R, Heatley G, Silverman ML (1993) Occult axillary lymph node metastases in "node-negative" breast carcinoma. Hum Pathol 24: 950-957
19. Roder JD, Böttcher K, Siewert JR, Busch R, Hermanek P, Meyer HJ, The German Gastric Carcinoma Study Group (1993) Prognostic factors in gastric carcinoma: results of the german gastric carcinoma study 1992: Cancer 72: 2089-2097
20. Schlag P, Buhl K, Schwarz V, Möller P, Herfarth C (1989) Die neue TNM-Klassifizierung und ihre Auswirkung auf die chirurgische Behandlung des Magencarcinoms. Chirurg 60: 8-15
21. Schremmer CN, Peek U (1976) Häufigkeit und Verteilung von Lymphknoten und Metastasen in den regionären axillaren Lymphzentren beim Brustdrüsenkrebs der Frau. Dtsch Gesundheitswes 31: 779-783
22. Shiu MH, Moore E, Sanders M, Huvos A, Freedman B, Goodbold J, Chaiyaphruk S, Wesdorp R, Murray F, Brennan MF (1987) Influence of the extent of resection on survival after curative treatment of gastric carcinoma: a retrospective multivariate analysis. Arch Surg 122: 1347-1351
23. Siewert JR, Lange J, Böttcher K, Becker K, Stier A (1986) Lymphadenektomie beim Magencarcinom. Langenbecks Arch Chir 368: 137-148
24. Siewert JR, Hölscher AH, Becker K, Gössner W (1987) Kardiacarcinom: Versuch einer therapeutisch relevanten Klassifikation. Chirurg 58: 25-32
25. Siewert JR, Böttcher K, Roder JD, Busch R, Hermanek P, Meyer HJ, The German Gastric Carcinoma Study Group (1993) Prognostic relevance of systematic lymph node dissection in gastric carcinoma. Br J Surg 80: 1015-1018
26. Søreide O, Lillestøl J, Viste A, Bjerkeset T (1982) Factors influencing survival in patients with cancer of the stomach. Acta Chir Scand 148: 367-372
27. Trojani M, Mascarel I de, Bonichon F, Coindre JM, Delsol G (1987) Micrometastases to axillary lymph nodes from carcinoma of breast: detection by immunohistochemistry and prognostic significance. Br J Cancer 55: 303-306
28. Turnbull RB, Kyle K, Watson FR, Spratt J (1967) Cancer of the colon: the influence of the no-touch isolation technique on surgical rates. Ann Surg 166: 420-427
29. Vollmer E, Shimamoto F, Krieg C, Grundmann E (1991) Macrophages/ reticulum cells in early and late phases of lymphogenous metastasis. In: Grundmann E, Vollmer E (Hrsg) Current topics in pathology: reaction patterns of the lymph node - reactions associated with neoplasia and immune deficient status. Springer, Berlin Heidelberg New York, pp 49-79
30. Woodcock-Mitchell J, Eichner R, Nelson WG, Sun TT (1982) Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol 95: 580-588