메뉴 건너뛰기




Volumn 26, Issue 1, 1997, Pages 9-21

Cytotoxicity of bile salts against biliary epithelium: A study in isolated bile ductule fragments and isolated perfused rat liver

Author keywords

[No Author keywords available]

Indexed keywords

BILE SALT; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; GLYCOCONJUGATE; LITHOCHOLIC ACID; TAURINE; URSODEOXYCHOLIC ACID;

EID: 0030926120     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510260102     Document Type: Article
Times cited : (97)

References (59)
  • 1
    • 0021178162 scopus 로고
    • Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties. Studies on isolated hepatocytes and lipid membrane vesicles
    • Scholmerich J, Becher MS, Schmidt K, Schubert R, Kremer B, Feldhaus S, Gerok W. Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties. Studies on isolated hepatocytes and lipid membrane vesicles. HEPATOLOGY 1984;4:661-666.
    • (1984) Hepatology , vol.4 , pp. 661-666
    • Scholmerich, J.1    Becher, M.S.2    Schmidt, K.3    Schubert, R.4    Kremer, B.5    Feldhaus, S.6    Gerok, W.7
  • 2
    • 0025790578 scopus 로고
    • Conjugates of ursodeoxycholic acid protect against cytotoxicity of more hydrophobic bile salts: In vitro studies in rat hepatocytes and human erythrocytes
    • Heuman DM, Pandak WM, Hylemon PB, Vlahcevic ZR. Conjugates of ursodeoxycholic acid protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytes. HEPATOLOGY 1991;14:920-926.
    • (1991) Hepatology , vol.14 , pp. 920-926
    • Heuman, D.M.1    Pandak, W.M.2    Hylemon, P.B.3    Vlahcevic, Z.R.4
  • 3
    • 0021742117 scopus 로고
    • Effect of chenodeoxycholic and ursodeoxycholic acids on isolated adult human hepatocytes
    • Miyazaki K, Nakayama F, Koga A. Effect of chenodeoxycholic and ursodeoxycholic acids on isolated adult human hepatocytes. Dig Dis Sci 1984;29:1123-1130.
    • (1984) Dig Dis Sci , vol.29 , pp. 1123-1130
    • Miyazaki, K.1    Nakayama, F.2    Koga, A.3
  • 4
    • 0027227827 scopus 로고
    • Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes
    • Spivey JR, Bronk SF, Gores G. Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. J Clin Invest 1993;92:17-24.
    • (1993) J Clin Invest , vol.92 , pp. 17-24
    • Spivey, J.R.1    Bronk, S.F.2    Gores, G.3
  • 5
    • 4244203336 scopus 로고
    • Effect of S-adenosyl-L-methionine (SAMe) reduced hepatotoxicity induced by hydrophobic bile salts (BS) in HepG2 cell line
    • Concari M, Guicciardi ME, Carubbi F, Bozzoli M, Tagliazucchi M, Crema G, Loria P, et al. Effect of S-adenosyl-L-methionine (SAMe) reduced hepatotoxicity induced by hydrophobic bile salts (BS) in HepG2 cell line [Abstract]. J Hepatol 1994;21:S77A.
    • (1994) J Hepatol , vol.21
    • Concari, M.1    Guicciardi, M.E.2    Carubbi, F.3    Bozzoli, M.4    Tagliazucchi, M.5    Crema, G.6    Loria, P.7
  • 7
    • 0025893620 scopus 로고
    • Protective effect of tauroursodeoxycholate against chenodeoxycholate-induced damage to cultured rabbit gastric cells
    • Ota S, Tsukahara H, Terano A, Hata Y, Hiraishi H, Mutoh H, Sugimoto T. Protective effect of tauroursodeoxycholate against chenodeoxycholate-induced damage to cultured rabbit gastric cells. Dig Dis Sci 1991; 30:409-416.
    • (1991) Dig Dis Sci , vol.30 , pp. 409-416
    • Ota, S.1    Tsukahara, H.2    Terano, A.3    Hata, Y.4    Hiraishi, H.5    Mutoh, H.6    Sugimoto, T.7
  • 8
    • 0027209627 scopus 로고
    • Hepatoprotective properties of ursodeoxycholic acid
    • Heuman DM. Hepatoprotective properties of ursodeoxycholic acid [Editorial]. Gastroenterology 1993;104:1865-1870.
    • (1993) Gastroenterology , vol.104 , pp. 1865-1870
    • Heuman, D.M.1
  • 9
    • 0025247125 scopus 로고
    • Hepatic injury induced by bile salts: Correlation between biochemical and morphological events
    • Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K. Hepatic injury induced by bile salts: correlation between biochemical and morphological events. HEPATOLOGY 1990;12:1216-1221.
    • (1990) Hepatology , vol.12 , pp. 1216-1221
    • Schmucker, D.L.1    Ohta, M.2    Kanai, S.3    Sato, Y.4    Kitani, K.5
  • 10
    • 0026086134 scopus 로고
    • Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat
    • Heuman DM, Scott Mills A, McCall J, Hylemon PB, Pandak WM, Vlahcevic R. Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat. Gastroenterology 1991;100:203-211.
    • (1991) Gastroenterology , vol.100 , pp. 203-211
    • Heuman, D.M.1    Scott Mills, A.2    McCall, J.3    Hylemon, P.B.4    Pandak, W.M.5    Vlahcevic, R.6
  • 11
    • 0018750844 scopus 로고
    • Choleretic and cholestatic effects of infused bile salts in the rat
    • Drew R, Priestly BG. Choleretic and cholestatic effects of infused bile salts in the rat. Experientia 1978;35:809-811.
    • (1978) Experientia , vol.35 , pp. 809-811
    • Drew, R.1    Priestly, B.G.2
  • 12
    • 0015046421 scopus 로고
    • Bile acid metabolism in mammals. Ultrastructural studies on the intrahepatic cholestasis induced by lithocholic and chenodeoxycholic acids in the rat
    • Miyai K, Price VM, Fisher MM. Bile acid metabolism in mammals. Ultrastructural studies on the intrahepatic cholestasis induced by lithocholic and chenodeoxycholic acids in the rat. Lab Invest 1971;24:292-302.
    • (1971) Lab Invest , vol.24 , pp. 292-302
    • Miyai, K.1    Price, V.M.2    Fisher, M.M.3
  • 13
    • 0342662084 scopus 로고
    • Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat
    • Kitani K, Ohta M, Kanai S. Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat. Am J Physiol 1985;248:G407-G417.
    • (1985) Am J Physiol , vol.248
    • Kitani, K.1    Ohta, M.2    Kanai, S.3
  • 14
    • 0027363563 scopus 로고
    • Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to a liver disease
    • Smit JJ, Schinkel AH, Oude Elferink RPJ, Groen AK, Wagenaar E, Van Deemter L, Ottenhoff R, et al. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to a liver disease. Cell 1993;75:451-462.
    • (1993) Cell , vol.75 , pp. 451-462
    • Smit, J.J.1    Schinkel, A.H.2    Oude Elferink, R.P.J.3    Groen, A.K.4    Wagenaar, E.5    Van Deemter, L.6    Ottenhoff, R.7
  • 15
    • 0011331012 scopus 로고
    • Cholestasis: Definition and classification of the major clinical forms
    • Gentilini P, Arias IM, McIntyre N, Rodes J, eds. Amsterdam: Elseevier Science B.V.
    • Sherlock S. Cholestasis: definition and classification of the major clinical forms. In: Gentilini P, Arias IM, McIntyre N, Rodes J, eds. Cholestasis. Amsterdam: Elseevier Science B.V., 1994:3-18.
    • (1994) Cholestasis , pp. 3-18
    • Sherlock, S.1
  • 16
    • 0027199388 scopus 로고
    • Tubulo-vesicular transcytotic pathway in rat biliary epithelium: A study in perfused liver and in isolated intrahepatic bile duct
    • Benedetti A, Marucci L, Bassotti C, Mancini R, Contucci S, Jezequel AM, Orlandi F. Tubulo-vesicular transcytotic pathway in rat biliary epithelium: a study in perfused liver and in isolated intrahepatic bile duct. HEPATOLOGY 1993;18:422-432.
    • (1993) Hepatology , vol.18 , pp. 422-432
    • Benedetti, A.1    Marucci, L.2    Bassotti, C.3    Mancini, R.4    Contucci, S.5    Jezequel, A.M.6    Orlandi, F.7
  • 18
    • 0024435974 scopus 로고
    • Isolation of a nonparenchymal liver cell fraction enriched in cells with biliary epithelial phenotypes
    • Alpini G, Lenzi R, Zhai WR, Liu MH, Slott PA, Paronetto F, Tavoloni N. Isolation of a nonparenchymal liver cell fraction enriched in cells with biliary epithelial phenotypes. Gastroenterology. 1989;97:1248-1260.
    • (1989) Gastroenterology , vol.97 , pp. 1248-1260
    • Alpini, G.1    Lenzi, R.2    Zhai, W.R.3    Liu, M.H.4    Slott, P.A.5    Paronetto, F.6    Tavoloni, N.7
  • 19
    • 0024441370 scopus 로고
    • Isolation and morphological characterization of bile duct epithelial cells from normal rat liver
    • Ishii M, Vroman BT, LaRusso NF. Isolation and morphological characterization of bile duct epithelial cells from normal rat liver. Gastroenterology 1989;97:1236-1247.
    • (1989) Gastroenterology , vol.97 , pp. 1236-1247
    • Ishii, M.1    Vroman, B.T.2    LaRusso, N.F.3
  • 20
    • 0027423533 scopus 로고
    • Regulation of bicarbonate-dependent ductular secretion assessed by lumenal micropuncture of isolated rodent intrahepatic intact bile ducts
    • Roberts SK, Kuntz SM, Gores GJ, La Russo NF. Regulation of bicarbonate-dependent ductular secretion assessed by lumenal micropuncture of isolated rodent intrahepatic intact bile ducts. Proc Natl Acad Sci U S A 1995;90:9080-9084.
    • (1995) Proc Natl Acad Sci U S A , vol.90 , pp. 9080-9084
    • Roberts, S.K.1    Kuntz, S.M.2    Gores, G.J.3    La Russo, N.F.4
  • 21
    • 0029864329 scopus 로고    scopus 로고
    • Morphological, molecular and functional heterogeneity of cholangiocytes from normal rat liver
    • Alpini G, Roberts SK, Kuntz SM, Ueno Y, Gubba S, Podila P, LeSage G, et al. Morphological, molecular and functional heterogeneity of cholangiocytes from normal rat liver. Gastroenterology 1996;110:1636-1643.
    • (1996) Gastroenterology , vol.110 , pp. 1636-1643
    • Alpini, G.1    Roberts, S.K.2    Kuntz, S.M.3    Ueno, Y.4    Gubba, S.5    Podila, P.6    LeSage, G.7
  • 23
    • 0019509145 scopus 로고
    • Separation of two populations of cells with gamma-glutamyl-transpeptidase from carcinogen-treated rat liver
    • Jacobs JMJ, Pretlow TP, Fausto N, Pitts A, Pretlow TG. Separation of two populations of cells with gamma-glutamyl-transpeptidase from carcinogen-treated rat liver. J Natl Cancer Inst 1981;66:967-973.
    • (1981) J Natl Cancer Inst , vol.66 , pp. 967-973
    • Jacobs, J.M.J.1    Pretlow, T.P.2    Fausto, N.3    Pitts, A.4    Pretlow, T.G.5
  • 24
    • 0026032696 scopus 로고
    • A simple method for the determination of lipid composition of human bile
    • Muraca M, Vilei MT, Micromi L, Petrini P. A simple method for the determination of lipid composition of human bile. J Lipid Res 1991; 32:371-379.
    • (1991) J Lipid Res , vol.32 , pp. 371-379
    • Muraca, M.1    Vilei, M.T.2    Micromi, L.3    Petrini, P.4
  • 25
    • 0014546946 scopus 로고
    • Correlated morphometric and biochemical studies on the liver cell
    • Weibel ER, Staubli W, Gnagi R, Hess FA. Correlated morphometric and biochemical studies on the liver cell. J Cell Biol 1969;42:68-91.
    • (1969) J Cell Biol , vol.42 , pp. 68-91
    • Weibel, E.R.1    Staubli, W.2    Gnagi, R.3    Hess, F.A.4
  • 26
    • 0021816123 scopus 로고
    • Effect of ursodeoxycholate-induced choleresis in taurine-deprived and taurine-supplemented rats
    • Kitani, K, Kanai S. Effect of ursodeoxycholate-induced choleresis in taurine-deprived and taurine-supplemented rats. Jpn J Physiol 1985;35: 443-462.
    • (1985) Jpn J Physiol , vol.35 , pp. 443-462
    • Kitani, K.1    Kanai, S.2
  • 27
    • 0019870988 scopus 로고
    • Taurine mobilizing effects of beta alanine and other inhibitors of taurine transport
    • Shaffer JE, Kocsis JJ. Taurine mobilizing effects of beta alanine and other inhibitors of taurine transport. Life Sci 1981;28:2727-2736.
    • (1981) Life Sci , vol.28 , pp. 2727-2736
    • Shaffer, J.E.1    Kocsis, J.J.2
  • 28
    • 0026069612 scopus 로고
    • Effect of UDCA on intracellular and biliary pH in isolated rat hepatocyte couplets and perfused livers
    • Strazzabosco M, Sakisaka S, Hayakawa T, Boyer JL. Effect of UDCA on intracellular and biliary pH in isolated rat hepatocyte couplets and perfused livers. Am J Physiol 1991;260:G58-G69.
    • (1991) Am J Physiol , vol.260
    • Strazzabosco, M.1    Sakisaka, S.2    Hayakawa, T.3    Boyer, J.L.4
  • 29
    • 0028934905 scopus 로고
    • Functional and ultrastructural features of ethanol/ bile salts interaction in the isolated perfused rat liver
    • Alvaro D, Benedetti A, Gigliozzi A, Bini A, Della Guardia P, La Rosa T, Jezequel AM, et al. Functional and ultrastructural features of ethanol/ bile salts interaction in the isolated perfused rat liver. HEPATOLOGY 1995;21:1120-1129.
    • (1995) Hepatology , vol.21 , pp. 1120-1129
    • Alvaro, D.1    Benedetti, A.2    Gigliozzi, A.3    Bini, A.4    Della Guardia, P.5    La Rosa, T.6    Jezequel, A.M.7
  • 30
    • 0028987042 scopus 로고
    • Effect of brefeldin A on transcytotic vesicular pathway and bile secretion: A study on the isolated perfused rat liver and isolated rat hepatocyte couplets
    • Alvaro D, Benedetti A, Gigliozzi A, Bini A, Furfaro S, Bassotti C, La Rosa T, Jezequel AM, Capocaccia L. Effect of brefeldin A on transcytotic vesicular pathway and bile secretion: A study on the isolated perfused rat liver and isolated rat hepatocyte couplets. HEPATOLOGY 1995;21: 450-459.
    • (1995) Hepatology , vol.21 , pp. 450-459
    • Alvaro, D.1    Benedetti, A.2    Gigliozzi, A.3    Bini, A.4    Furfaro, S.5    Bassotti, C.6    La Rosa, T.7    Jezequel, A.M.8    Capocaccia, L.9
  • 31
    • 72849179070 scopus 로고
    • Enzymatic analysis of steroid hormones
    • Talalay P. Enzymatic analysis of steroid hormones. Methods Biochem Anal 1960;8:119-149.
    • (1960) Methods Biochem Anal , vol.8 , pp. 119-149
    • Talalay, P.1
  • 32
    • 0017656417 scopus 로고
    • A new enzymatic method for determination of serum choline-containing phospholipids
    • Takayama M, Itoh S, Nagasaki T, Tanimizu I. A new enzymatic method for determination of serum choline-containing phospholipids. Clin Chim Acta 1977;79:93-98.
    • (1977) Clin Chim Acta , vol.79 , pp. 93-98
    • Takayama, M.1    Itoh, S.2    Nagasaki, T.3    Tanimizu, I.4
  • 33
    • 0000836947 scopus 로고
    • Thin-layer adsorption chromatography of free and conjugated bile acids on silicic acid
    • Hofmann A.F. Thin-layer adsorption chromatography of free and conjugated bile acids on silicic acid. J Lipid Res 1962;2:127-128.
    • (1962) J Lipid Res , vol.2 , pp. 127-128
    • Hofmann, A.F.1
  • 34
    • 0022530992 scopus 로고
    • Glucuronides of monohydroxylated bile acids: Specificity of microsomal glucuronyl-transferase for the glucuronidation site, c-3 configuration, and side chain length
    • Radominska-Pyrek A, Ziminiak R, Chari M, Golunski E, Lester R, Pyrek St. Glucuronides of monohydroxylated bile acids: specificity of microsomal glucuronyl-transferase for the glucuronidation site, c-3 configuration, and side chain length. J Lipid Res 1986;27:89-101.
    • (1986) J Lipid Res , vol.27 , pp. 89-101
    • Radominska-Pyrek, A.1    Ziminiak, R.2    Chari, M.3    Golunski, E.4    Lester, R.5    Pyrek, St.6
  • 35
    • 0026020912 scopus 로고
    • Cholestasis induced by lithocholate and its glucuronide: Their biliary excretion and metabolism
    • Takikawa H, Ohki H, Sano N, Kasama T, Yamanaka M. Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism. Biochim Biophys Acta 1991;1081:39-44.
    • (1991) Biochim Biophys Acta , vol.1081 , pp. 39-44
    • Takikawa, H.1    Ohki, H.2    Sano, N.3    Kasama, T.4    Yamanaka, M.5
  • 36
    • 0023160448 scopus 로고
    • Improved method for measuring the glycine and taurine conjugates of bile salts by high-performance liquid chromatography with tauro 7α-12α-dihydroxy-5β-cholanic acid as internal standard
    • Cantafora A, Di Biase A, Alvaro D, Angelico M. Improved method for measuring the glycine and taurine conjugates of bile salts by high-performance liquid chromatography with tauro 7α-12α-dihydroxy-5β-cholanic acid as internal standard. J Chromatogr 1987;386:367-370.
    • (1987) J Chromatogr , vol.386 , pp. 367-370
    • Cantafora, A.1    Di Biase, A.2    Alvaro, D.3    Angelico, M.4
  • 38
    • 0020055254 scopus 로고
    • The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholesterol-solubilizing capacities
    • Armstrong MJ, Carey MC. The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholesterol-solubilizing capacities. J Lipid Res 1982;23:70-80.
    • (1982) J Lipid Res , vol.23 , pp. 70-80
    • Armstrong, M.J.1    Carey, M.C.2
  • 39
    • 0028091169 scopus 로고
    • Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria
    • Krahenbuhl S, Talos C, Fischer S, Reichen J. Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria. HEPATOLOGY 1994;19:471-479.
    • (1994) Hepatology , vol.19 , pp. 471-479
    • Krahenbuhl, S.1    Talos, C.2    Fischer, S.3    Reichen, J.4
  • 40
    • 12644277066 scopus 로고
    • Ursodeoxycholate (UDC) prevents glutamate dehydrogenase (GLDH) release of isolated liver mitochondria by chenodeoxycholate (CDCA)
    • Guldutuna S, Elze A, Bhatti S, Imhof M, You T, Zimmer G, Leuschner U. Ursodeoxycholate (UDC) prevents glutamate dehydrogenase (GLDH) release of isolated liver mitochondria by chenodeoxycholate (CDCA)[Abstract]. Gastroenterology 1993;104:A361.
    • (1993) Gastroenterology , vol.104
    • Guldutuna, S.1    Elze, A.2    Bhatti, S.3    Imhof, M.4    You, T.5    Zimmer, G.6    Leuschner, U.7
  • 41
    • 17344369251 scopus 로고    scopus 로고
    • Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt-induced apoptosis
    • Roberts LR, Patel T, Bronk SF, Gores GJ. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt-induced apoptosis [Abstract]. HEPATOLOGY 1996;24:508A.
    • (1996) Hepatology , vol.24
    • Roberts, L.R.1    Patel, T.2    Bronk, S.F.3    Gores, G.J.4
  • 43
    • 0342437058 scopus 로고    scopus 로고
    • Genetic and functional expression of the ileal Na-dependent bile acid transporter and 14 kD cytosolic bile acid binding protein in large but not small cholangiocytes from normal rat liver
    • Alpini G, Glaser S, Robertson WE, Phinizy IL, Rodgers R, Le Sage GD. Genetic and functional expression of the ileal Na-dependent bile acid transporter and 14 kD cytosolic bile acid binding protein in large but not small cholangiocytes from normal rat liver [Abstract]. HEPATOLOGY 1996;24:255A.
    • (1996) Hepatology , vol.24
    • Alpini, G.1    Glaser, S.2    Robertson, W.E.3    Phinizy, I.L.4    Rodgers, R.5    Le Sage, G.D.6
  • 45
    • 0002661606 scopus 로고
    • Bile acids
    • Arias IM, Boyer JL, Fausto N, Jakoby WB, Dchachter D, Shafritz DA, eds. The Liver. New York: Raven
    • Hofmann AF. Bile acids. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Dchachter D, Shafritz DA, eds. The Liver. Biology and Pathobiology. Third Edition. New York: Raven, 1994:677-718.
    • (1994) Biology and Pathobiology. Third Edition , pp. 677-718
    • Hofmann, A.F.1
  • 46
    • 0002310338 scopus 로고
    • Enterohepatic circulation
    • Arias IM, Boyer JL, Fausto N, Jakoby WB, Dchachter D, Shafritz DA, eds. The Liver. New York: Raven
    • Carey MC, Duane WC. Enterohepatic circulation. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Dchachter D, Shafritz DA, eds. The Liver. Biology and Pathobiology. Third Edition. New York: Raven, 1994:719-768.
    • (1994) Biology and Pathobiology. Third Edition , pp. 719-768
    • Carey, M.C.1    Duane, W.C.2
  • 47
    • 0018371155 scopus 로고
    • Pathophysiology of the enterohepatic circulation of bile acids
    • Matern S, Jerok W. Pathophysiology of the enterohepatic circulation of bile acids. Rev Physiol Pharmacol 1979;85:126-204.
    • (1979) Rev Physiol Pharmacol , vol.85 , pp. 126-204
    • Matern, S.1    Jerok, W.2
  • 48
    • 12644293522 scopus 로고
    • Bacteria and the small intestine
    • Card WI, Creamer G, eds. London: Butterworth
    • Tabaqchali S, Booth CC. Bacteria and the small intestine. In: Card WI, Creamer G, eds. Modern Trend in Gastroenterology. London: Butterworth, 1970:143-179.
    • (1970) Modern Trend in Gastroenterology , pp. 143-179
    • Tabaqchali, S.1    Booth, C.C.2
  • 49
    • 12644313858 scopus 로고
    • Serum levels of individual bile acids in portal venous and systemic circulation during treatment with chenodeoxycholic acid and cholic acid
    • Paumgartner G, Stiehl A, Gerok W, eds. Lancaster: MTP Press
    • Angelin B, Ahlberg J, Björkhem I, Einarrson K, Ewerth S. Serum levels of individual bile acids in portal venous and systemic circulation during treatment with chenodeoxycholic acid and cholic acid. In: Paumgartner G, Stiehl A, Gerok W, eds. Biological Effects of Bile Acids. Lancaster: MTP Press, 1979:107-108.
    • (1979) Biological Effects of Bile Acids , pp. 107-108
    • Angelin, B.1    Ahlberg, J.2    Björkhem, I.3    Einarrson, K.4    Ewerth, S.5
  • 50
    • 12644255342 scopus 로고
    • Effect of bile acid hydrophobicity on biliary transit time and intracellular mobility: A comparison of four fluorescent bile acid analogues
    • LeSage GD, Schteingart CD, Hofmann AF. Effect of bile acid hydrophobicity on biliary transit time and intracellular mobility: a comparison of four fluorescent bile acid analogues [Abstract]. Gastroenterology 1994;106:A929.
    • (1994) Gastroenterology , vol.106
    • Lesage, G.D.1    Schteingart, C.D.2    Hofmann, A.F.3
  • 51
    • 12644284165 scopus 로고
    • Normal histology and ultrastrucure
    • Millward-Saddler GH, Wright R, Arthur MJP, eds. Philadelphia: Saunders
    • Millward GH, Jezequel AM. Normal histology and ultrastrucure. In: Millward-Saddler GH, Wright R, Arthur MJP, eds. Liver and Biliary Diseases. Third edition. Philadelphia: Saunders, 1992:12-43.
    • (1992) Liver and Biliary Diseases. Third Edition , pp. 12-43
    • Millward, G.H.1    Jezequel, A.M.2
  • 52
    • 0018167114 scopus 로고
    • Pathogenesis of lithocholate- and taurolithocholate-induced intrahepatic cholestasis in rats
    • Kakis G, Yousef IM. Pathogenesis of lithocholate- and taurolithocholate-induced intrahepatic cholestasis in rats. Gastroenterology 1978;75:595-607.
    • (1978) Gastroenterology , vol.75 , pp. 595-607
    • Kakis, G.1    Yousef, I.M.2
  • 53
    • 0025732697 scopus 로고
    • Hypercholeresis induced by unconjugated bile acid infusion correlates with recovery in bile of unconjugated bile acids
    • Gurantz D, Schteingart CD, Hagey LR, Steinbach JH, Grotmol T, Hofmann AF. Hypercholeresis induced by unconjugated bile acid infusion correlates with recovery in bile of unconjugated bile acids. HEPATOLOGY 1991;13:540-550.
    • (1991) Hepatology , vol.13 , pp. 540-550
    • Gurantz, D.1    Schteingart, C.D.2    Hagey, L.R.3    Steinbach, J.H.4    Grotmol, T.5    Hofmann, A.F.6
  • 54
    • 0019294767 scopus 로고
    • Hypercholeresis induced by ursodeoxycholic acid and 7-Ketolithocholic acid in the rat: Possible role of bicarbonate transport
    • Dumont M, Erlinger S, Uchman S. Hypercholeresis induced by ursodeoxycholic acid and 7-Ketolithocholic acid in the rat: possible role of bicarbonate transport. Gastroenterology 1980;79:82-89.
    • (1980) Gastroenterology , vol.79 , pp. 82-89
    • Dumont, M.1    Erlinger, S.2    Uchman, S.3
  • 55
    • 0025352101 scopus 로고
    • Hypercholeretic bile acids: A clue to the mechanism?
    • Erlinger S. Hypercholeretic bile acids: A clue to the mechanism? HEPATOLOGY 1990;11:888-890.
    • (1990) Hepatology , vol.11 , pp. 888-890
    • Erlinger, S.1
  • 56
    • 0027424160 scopus 로고
    • Disappearing intrahepatic bile ducts. The syndromes and their mechanisms
    • Woolf GM, Vierling JM, Disappearing intrahepatic bile ducts. The syndromes and their mechanisms. Semin Liver Dis 1993;13:261-275.
    • (1993) Semin Liver Dis , vol.13 , pp. 261-275
    • Woolf, G.M.1    Vierling, J.M.2
  • 57
    • 0021226578 scopus 로고
    • Aqueous bile salt -lecithin cholesterol systems: Equilibrium aspects
    • Carey MC. Aqueous bile salt -lecithin cholesterol systems: equilibrium aspects. HEPATOLOGY 1984;4:151S-154S.
    • (1984) Hepatology , vol.4
    • Carey, M.C.1
  • 58
    • 0007513319 scopus 로고
    • Self- Diffusion study of bile salt-monoolein micelles. Determination of the intermicellar bile salt concentration
    • Lindheimer M, Montet JC, Bontemps R, Rouviere J, Brun B. Self- diffusion study of bile salt-monoolein micelles. Determination of the intermicellar bile salt concentration. J Chim Phys 1983;80:315-323.
    • (1983) J Chim Phys , vol.80 , pp. 315-323
    • Lindheimer, M.1    Montet, J.C.2    Bontemps, R.3    Rouviere, J.4    Brun, B.5
  • 59
    • 0028850221 scopus 로고
    • The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology
    • Oude Elferink RPJ, Groen AH. The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology. J Hepatol 1995;23:617-625.
    • (1995) J Hepatol , vol.23 , pp. 617-625
    • Oude Elferink, R.P.J.1    Groen, A.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.