Intermediate filament linker proteins

Journal of General Physiology

Volumn , Issue 50TH ANN. SYMP., 1997, Pages 141-148

  Fuchs, Elaine ^a   Yang, Yanmin ^a   Dowling, James ^a   Kouklis, Panos ^a   Smith, Elizabeth ^a   Guo, Lifei ^a   Yu, Qian Chun ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINK PROTEIN; AUTOANTIGEN; BPAG1 PROTEIN, HUMAN; CARRIER PROTEIN; COLLAGEN; COLLAGEN TYPE 17; CYTOSKELETON PROTEIN; DESMOPLAKIN; DST PROTEIN, MOUSE; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN; NONFIBRILLAR COLLAGEN; PLEC1 PROTEIN, HUMAN; PLEC1 PROTEIN, MOUSE; PLECTIN;

ANIMAL CELL; CONFERENCE PAPER; CYTOSKELETON; DESMOSOME; INTERMEDIATE FILAMENT; NONHUMAN; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; ANIMAL; CHEMISTRY; EPITHELIUM; HUMAN; METABOLISM; MOUSE; REVIEW; ULTRASTRUCTURE;

ANIMALS; AUTOANTIGENS; CARRIER PROTEINS; COLLAGEN; CYTOSKELETAL PROTEINS; DESMOPLAKINS; DESMOSOMES; EPITHELIUM; HUMANS; INTERMEDIATE FILAMENT PROTEINS; MICE; NERVE TISSUE PROTEINS; NON-FIBRILLAR COLLAGENS; PLECTIN;

EID: 0030926092     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (39)

1. Bonifas, J.M., A.L. Rothman, and E.H. Epstein. 1991. Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities. Science. 254:1202-1205.
2. Bornslaeger, E.A., C.M. Corcoran, T.S. Stappenbeck, and K.J. Green. 1996. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell in-terfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134:985-1001.
3. Brown, A., G. Bernier, M. Mathieu, J. Rossant, and R. Kothary. 1995a. The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nature Genet. 10:301-306.
4. Brown, A., G. Dalpe, M. Mathieu, and R. Kothary. 1995b. Cloning and characterization of the neural isoforms of human dystonin. Genomics. 29:777-780.
5. Campbell, R.M., and A.C. Peterson. 1992. An intrinsic neuronal defect operates in dystonia musculorum: a study of dt/dt<= =>+/+ chimeras. Neuron. 9:693-703.
6. Chan, Y.-M., Q.-C. Yu, A. Christiano, J. Uitto, R.S. Kucherlapati, J. LeBlanc-Straceski, and E. Fuchs. 1994. Mutations in the non-helical linker segment L1-2 of keratin 5 in patients with Weber-Cockayne Epidermolysis Bullosa Simplex. J. Cell Sci. 107:765-774.
7. Coulombe, P.A., M.E. Hutton, A. Letai, A. Hebert, A.S. Paller, and E. Fuchs. 1991. Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Cell. 66:1301-1311.
8. Dowling, J., Y. Yang, R. Wollmann, L.F. Reichardt, and E. Fuchs. 1997. Developmental expression of BPAG1-n: insights into the spastic ataxia and gross neurologic degeneration in Dystonia musculorum mice. Dev. Biol. In press.
9. Duchen, L.W. 1976. Dystonia Musculorum: an inherited disease of the nervous system in the mouse. Adv. Neurol. 14:353-365.
10. Duchen, L.W., and S.J. Strich. 1964. Clinical and pathological studies of an hereditary neuropathy in mice (dystonia musculorum). Brain. 87:367-378.
11. Fine, J.D., E.A. Bauer, R.A. Briggaman, D.M. Carter, R.A.J. Eady, N.B. Esterly, K.A. Hoibrook, S. Hurwitz, L. Johnson, A. Lin, R. Pearson, and V.P. Sybert. 1991. Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa. J. Am. Acad. Dermatol. 24:119-135.
12. Fitzpatrick, T.B., A.Z. Eisen, K. Wolff, I.M. Freedberg, and K.F. Austen. 1993. Dermatology in General Medicine, Fourth ed., Vol. I and II. McGraw-Hill, Inc., New York.
13. Foisner, R., P. Traub, and G. Wiche. 1991. Protein kinase A- and protein kinase C-regulated interaction of plectin with lamin B and vimentin. frac. Natl. Acad. Sci. USA. 88:3812-3816.
14. Foisner, R., W. Bohn, K. Mannweiler, and G. Wiche. 1995. Distribution and ultrastructure of plectin arrays in subclones of rat glioma Q cells differing in intermediate filament protein (vimentin) expression. J. Struct. Biol. 115:304-317.
15. Garrod, D.R. 1993. Desmosomes and hemidesmosomes. Curr. Opin. Cell Biol. 5:30-40.
16. Green, K.J., M.L.A. Virata, G.W. Elgart, J.R. Stanley, and D.A.D. Parry. 1992. Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin: members of a new gene family involved in organization of intermediate filaments. Int. J. Biol. Macromol. 14:145-153.
17. Guo, L., L. Degenstein, J. Dowling, Q.-C. Yu, R. Wollmann, B. Perman, and E. Fuchs. 1995. Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified squamous epithelia and severe neurologic degeneration. Cell. 81:233-243.
18. Janota, I. 1972. Ultrastructural studies of an hereditary sensory neuropathy in mice (Dystonia Musculorum). Brain. 95:529-536.
19. Jongstra-Bilen, J., P.A. Janmey, J.H. Hartwig, S. Galca, and J. Jongstra. 1992. The lympho-cyte-specific protein LSP1 binds to F-actin and to the cytoskeleton through its COOH-terminal basic domain. J. Cell Biol. 118:1443-1453.
20. Kouklis, P., E. Hutton, and E. Fuchs. 1994. Making the connection: keratin intermediate filaments and desmosome proteins. J. Cell Biol. 127:1049-1060.
21. Lo, S.H., P.A. Janmey, J.H. Hartwig, and L.B. Chen. 1994. Interactions of tensin with actin and identification of its three distinct actin-binding domains. J. Cell Biol. 125:1067-1075.
22. Luna, E.J., and A.L. Hitt. 1992. Cytoskeleton-plasma membrane interactions. Science. 258:955-963.
23. McLean, W.H.I., L. Pulkkinen, F.J.D. Smith, E.L. Rugg, E.B. Lane, F. Bullrich, R.E. Burgeson, S. Amano, D.L. Hudson, K. Owaribe, et al. 1996. Loss of plectin causes epidermolysis bulllosa with muscular dystrophy: cDNA cloning and genomic organization. Genes Dev. 10:1724-1735.
24. Messer, A., and N.L. Strominger. 1980. An allele of the mouse mutant dystonia musculorum exhibits lesions in red nucleus and striatum. Neuroscience. 5:543-549.
25. Owaribe, K., J. Kartenbeck, S. Stumpp, T.M. Magin, T. Krieg, L.A. Diaz, and W.W. Franke. 1990. The hemidesmosomal plaque I. Characterization of a major constituent protein as a differentiation marker for certain forms of epithelia. Differentiation. 45:207-220.
26. Rugg, E.L., W.H.I. McLean, E.B. Lane, R. Pitera, J.R. McMillan, P.J.C. Dopping-Hepenstal, H.A. Navsaria, I.M. Leigh, and R.A.J. Eady. 1994. A functional "knockout" of human keratin 14. Genes Dev. 8:2563-2573.
27. Sarria, A.J., S.K. Nordeen, and R.M. Evans. 1990. Regulated expression of vimentin cDNA in cells in the presence and absence of a preexisting vimentin filament network. J. Cell Biol. 111:553-565.
28. Schwarz, M.A., K. Owaribe, J. Kartenbeck, and W.W. Franke. 1990. Desmosomes and hemidesmosomes: constitutive molecular components. Annu. Rev. Cell Biol. 6:461-491.
29. Seifert, G.J., D. Lawson, and G. Wiche. 1992. Immunolocalization of the intermediate filament-associated protein plectin at focal contacts and actin stress fibers. Eur. J. Cell Biol. 59:138-147.
30. Smith, F.J.D., R.A.J. Eady, I.M. Leigh, J.R. McMillan, E.L. Rugg, D.P. Kelsell, S.P. Bryant, N.K. Spurr, J.F. Geddes, G. Kirtschig, et al. 1996. Plectin deficiency results in muscular dystrophy with epidermolysis bullosa. Nature Genet. 13:450-457.
31. Sotelo, C., and J.L. Guenet. 1988. Pathologic changes in the CNS of dystonia musculorum mutant mouse: an animal model for human spinocerebellar ataxia. Neuroscience. 27:403-424.
32. Stanley, J.R. 1993. Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion. Adv. Immunol. 53:291-325.
33. Stappenbeck, T.S., and K.J. Green. 1992. The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells. J. Cell Biol. 116:1197-1209.
34. Stappenbeck, T.S., J.A. Lamb, C.M. Corcoran, and K.J. Green. 1994. Phosphorylation of the desmoplakin COOH terminus negatively regulates its interaction with keratin intermediate filament networks. J. Biol. Chem. 269:29351-29354.
35. Sugi, T., T. Hashimoto, T. Hibi, and T. Nishikawa. 1989. Production of human monoclonal anti-basement membrane zone (BMZ) antibodies from a patient with bullous pemphigoid (BP) by Epstein-Barr virus transformation. J. Clin. Invest. 84:1050-1055.
36. Tamai, K., D. Sawamura, H.C. Do, Y. Tamai, K. Li, and J. Uitto. 1993. The human 230-kD bullous pemphigoid antigen gene (BPAG1): exon-intron organization and identification of regulatory tissue specific elements in the promoter region. J. Clin. Invest. 92:814-822.
37. Vassar R., P.A. Coulombe, L. Degenstein, K. Albers, and E. Fuchs. 1991. Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell. 64:365-380.
38. Wiche, G., D. Gromov, A. Donovan, M.J. Castanon, and E. Fuchs. 1993. Expression of plectin mutant cDNA in cultured cells indicates a role of COOH-terminal domain in intermediate filament association. J. Cell Biol. 121:607-619.
39. Yang, Y., J. Dowling, Q.-C. Yu, P. Kouklis, D.W. Cleveland, and E. Fuchs. 1996. An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell. 86:655-665.