Subacute toxicity of ebrotidine in rats and dogs

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 4 A SPEC. ISSUE, 1997, Pages 492-497

  Romero, Alfonso ^a,b   Grau, Maria Teresa ^a   Villamayor, Frederic ^a   Sacristán, Aurelio ^a   Ortiz, José A ^a  

^a Centro de Investigaciones Farmaceuticos Grupo Ferrer   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

CAS 100981 43 9; Ebrotidine; FI 3542, subacute toxicity; H2 Receptor antagonist

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; CIMETIDINE; EBROTIDINE; LACTATE DEHYDROGENASE; RANITIDINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG TOLERANCE; FEMALE; HEMATOCRIT; HISTOPATHOLOGY; LIVER WEIGHT; MALE; NONHUMAN; RAT; RECTUM PROLAPSE; SPECIES DIFFERENCE; STOMACH ACID SECRETION; TOXICITY TESTING;

ANIMALS; BENZENESULFONATES; BLOOD CHEMICAL ANALYSIS; BODY WEIGHT; DOGS; EATING; FEMALE; HISTAMINE H2 ANTAGONISTS; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLES; URINALYSIS;

EID: 0030925504     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

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2. Inglis, J. K., Introduction to Laboratory Animal Science and Technology, Pergamon Press, Oxford (1980)
3. Leslie, G. B., Walker, T. F., Excerpta Med. 416, 24 (1977)
4. OECD: Lignes directrices de l'OCDE pour les essais de produits chimiques, Paris (1981)
5. Tamura, J., Sato, N., Ezaki, H. et al., J. Toxicol. Sci. 8, 1 (1983)