Interaction between carbamazepine and bromperidol

European Journal of Clinical Pharmacology

Volumn 52, Issue 3, 1997, Pages 219-222

  Otani, K ^a   Ishida, M ^a   Yasui, N ^a   Kondo, T ^a   Mihara, K ^a   Suzuki, A ^a   Furukori, H ^a   Kaneko, S ^a   Inoue, Y ^b  

^a HIROSAKI UNIVERSITY HOSPITAL   (Japan)

^b Pharmaceutical Technology Center   (Japan)

Author keywords

Bromperidol; Carbamazepine; Plasma concentration; Reduced; bromperidol

Indexed keywords

BIPERIDEN; BROMPERIDOL; CARBAMAZEPINE; DRUG METABOLITE; FLUNITRAZEPAM; TRIHEXYPHENIDYL;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG POTENTIATION; DRUG STRUCTURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; RASH; SCHIZOPHRENIA; SOMNOLENCE;

ADULT; ANALGESICS, NON-NARCOTIC; ANTIPSYCHOTIC AGENTS; CARBAMAZEPINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; FEMALE; HALOPERIDOL; HUMANS; MALE; MIDDLE AGED; SCHIZOPHRENIA;

EID: 0030925373     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050277     Document Type: Article

References (19)

1. Arana GW, Goff DC, Friedman H, Ornsteen M, Greenblatt DJ, Black B, Shader RI (1986) Does carbamazepine-induced reduction of plasma haloperidol levels worsen psychotic symptoms? Am J Psychiatry 143: 650-651
2. Benfield P, Ward A, Clark BG, Jue SG (1988) Bromperidol. A preliminary review of its pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs 35: 670-684
3. Bertilsson L, Tomson T (1986) Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10, 11-epoxide. An update. Clin Pharmacokinet 11: 177-198
4. Brosen K, Kragh-Sorensen P (1993) Concomitant intake of nortriptyline and carbamazepine. Ther Drug Monit 15: 258-260
5. Guy W (1976) Clinical global impressions. In: ECDEU Assessment Manual for Psychopharmacology. National Institute of Mental Health, Rockville, MD, pp 218-222
6. Hikida K, Inoue Y, Miyazaki T, Kojima N, Ohkura Y (1989) Determination of bromperidol in serum by automated column-switching high-performance liquid chromatography. J Chromatogr 495: 227-234
7. Jann MW, Ereshefsky L, Saklad SR, Seidel DR, Davis CM, Burch NR, Bowden CL (1985) Effects of carbamazepine on plasma haloperidol levels. J Clin Psychopharmacol 5: 106-109
8. Kidron R, Averbuch I, Klein E, Belmaker RH (1985) Carbamazepine-induced reduction of blood levels of haloperidol in chronic schizophrenia. Biol Psychiatry 20: 199-228
9. Lingjaerde O, Ahlfors UG, Bech P, Dencker SJ, Elgen K (1987) The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand 76 (Suppl 334): 7-100
10. Otani K, Yasui N, Kaneko S, Ohkubo T, Sugawara K (1996a) Carbamazepine augmentation therapy in three patients with trazodone-resistant unipolar depression. Int Clin Psychopharmacol 11: 55-57
11. Otani K, Ishida M, Kaneko S, Mihara K, Ohkubo T, Osanai T, Sugawara (1996b) Effects of carbamazepine coadministration on plasma concentrations of trazdone and its active metabolite, m-chlorophenylpiperazine. Ther Drug Monit 18: 164-167
12. Post RM, Ketter TA, Pazzaglia PJ, Denicoff K, Marangell L, George MS (1994) Anticonvulsants in refractory mood disorders. In: Nolen WA, Zohar J, Roose SP, Amsterdam JD (eds) Refractory depression: current strategies and future directions. John Wiley, Chichester, pp 97-114
13. Siris SG (1993) Adjunctive medication in the maintenance treatment of schizophrenia and its conceptual implications. Br J Psychiatry 163 (Suppl 22): 66-78
14. Someya T, Inaba T, Tyndale RF, Tang SW, Takahashi S (1991) Conversion of bromperidol to reduced bromperidol in human liver. Neuropsychopharmacology 5: 177-182
15. Spina E, Avenoso A, Campo GM, Caputi AP, Perucca E (1995) The effect of carbamazepine on the 2-hydroxylation of desipramine. Psychopharmacology 117: 413-416
16. Tiihonen J, Vartiainen H, Hakola P (1995) Carbamazepine-induced changes in plasma levels of neuroleptics. Pharmacopsychiatry 28: 26-28
17. Wietholtz H, Zysset T, Kreiten K, Kohl D, Buchsel R, Matern S (1989) Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism. Eur J Clin Pharmacol 36: 401-406
18. Wong FA, Bateman CP, Shaw CJ, Patrick JE (1983) Biotransformation of bromperidol in rat, dog, and man. Drug Metab Disp 11: 301-307
19. Yeu Q-Y, Tomson T, Sawe J (1994) Carbamazepine and cigarette smoking induce differentially the metabolism of codeine in man. Pharmacogenetics 4: 193-198