Mapping of the plasminogen binding site of streptokinase with short synthetic peptides

Protein Science

Volumn 6, Issue 6, 1997, Pages 1284-1292

  Nihalani, Deepak ^a   Raghava, G P S ^a   Sahni, Girish ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

Active site; Peptide walking; Plasminogen; Plasminogen binding; Streptokinase; Streptokinase derived peptides

Indexed keywords

EPITOPE; PLASMINOGEN; STREPTOKINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME LINKED IMMUNOSORBENT ASSAY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEQUENTIAL ANALYSIS;

BOVINAE;

EID: 0030925283     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560060616     Document Type: Article

References (35)

1. Bayley PM, Findlay WA, Martin SR. 1996. Target recognition by calmodulin: Dissecting the kinetics and affinity of interaction using short peptide sequences. Protein Sci 5:1215-1228.
2. Beatty JD, Beatty BG, Vlahos WG. 1987. Measurement of monoclonal antibody affinity by non-competitive enzyme-immunoassay. J Immunol Methods 100:173-179.
3. Bradford MM. 1976. A rapid method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Biochemistry 72:248-254.
4. Castellino FJ. 1981. Recent advances in the chemistry of the fibrinolytic system. Chem Rev 81:431-446.
5. Dawson KM, Marshall JM, Raper RH, Gilbert RJ, Ponting CP. 1994. Substitution of arginine 719 for glutamic acid in human plasminogen substantially reduces its affinity for streptokinase. Biochemistry 33:12042-12047.
6. Deutch DG, Mertz ET. 1970. Plasminogen: Purification from human plasma by affinity chromatography. Science 170:1095-1096.
7. Fabian H, Naumann D, Misselwitz R, Ristau O, Gerlach D, Wefle H. 1992. Secondary structure of streptokinase in aqueous solution: A fourier transform infrared spectroscopic study. Biochemistry 31:6532-6538.
8. Findlay JBC, Geisow MJ. 1989. Protein sequencing: A practical approach. Oxford: IRL Press.
9. ISIS-3. 1992. Third international study of infract survival collaborative group. A randomized comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,229 cases of suspected acute myocardial infarction. The Lancet 339:753-781.
10. Jackson KW, Esmon N, Tang T. 1981. Streptokinase and staphylokinase. Methods Enzymol 80:387-394.
11. Joseph G, Pick E. 1995. "Peptide Walking" is a novel method for mapping functional domains in proteins. J Biol Chem 270:29079-29082.
12. Malke H, Roe B, Ferretti JJ. 1985. Nucleotide sequence of the streptokinase gene from Streptococcus equisimilis H46A. Gene 34:357-362.
13. Malke H, Roe B, Ferretti JJ. 1987. Streptokinase: Expression of altered forms. In: Ferreti JJ, Curtis R III, eds. Streptococcal genetics. Washington, DC: American Society for Microbiology. pp 143-149.
14. Marder VJ. 1993. Recombinant streptokinase: Opportunity for an improved agent. Blood Coagulation and Fibrinolysis 4:1039-1040.
15. Markus G, Werkheiser WC. 1964. The interaction of streptokinase with plasminogen: Functional properties of the activated enzyme. J Biol Chem 239:2637-2643.
16. McClintock DK, Bell PH. 1971. The mechanism of activation of human plasminogen by streptokinase. Biochem Biophys Res Commun 43:694-702.
17. Misselwitz R, Kraft R, Kosta R, Fabian H, Welfle K, Pfeil W, Welfle H, Gerlach D. 1992. Limited proteolysis of streptokinase and properties of some fragments. Int J Biol Macromol 14:107-116.
18. Mohri H, Tanabe J, Katoh K, Okubo T. 1996. Identification of a novel binding site to the integrin alpha-II b beta-3 located in the C-terminal heparin-binding domain of human plasma fibronectin. J Biol Chem 271:15724-15728.
19. Nihalani D, Sahni G. 1995. Streptokinase contains two independent plasminogen-binding sites. Biochem Biophys Res Commun 217:1245-1254.
20. Parrado J, Conejero-Lara F, Smith RAG, Marshall JM, Ponting CP, Dobson CM. 1996. The domain organization of streptokinase: Nuclear magnetic resonance, circular dichroism, and functional characterization of proteolytic fragments. Protein Sci 5:693-704.
21. Radek JT, Castellino FJ. 1989. Conformational properties of streptokinase. J Biol Chem 264:9915-9922.
22. Radek JT, Davidson JD, Castellino FJ. 1993. Streptokinase-plasmin(ogen) activator assays. Methods Enzymol 223:145-155.
23. Reddy KNN, Markus G. 1972. Mechanism of activation human plasminogen by streptokinase. J Biol Chem 247:1683-1691.
24. Reed GL, Kussi P, Parhami-Seren B. 1993. A functional analysis of the antigenicity of streptokinase using monoclonal antibody mapping and recombinant streptokinase fragments. J Immunol 150:4407-4415.
25. Reed GL, Lin LF, Parhami-Seren B, Kussie P. 1995. Identification of a plasminogen binding region in streptokinase that is necessary for the creation of a functional streptkinase-plasminogen activator complex. Biochemistry 34:10266-10271.
26. Robbins KC, Summaria L, Wohl RC. 1981. Human plasmin. Methods Enzymol 80:379-387.
27. Rodriguez P, Fuentes P, Barro M, Alvarez JG, Munoz E, Collen D, Lijnen HR. 1995. Structural domains of streptokinase involved in the interaction with plasminogen. Eur J Biochem 229:83-90.
28. Rodriguez P, Fuentes D, Munoz E, Rivero D, Orta D, Alburquerque S, Perez S, Bestada V, Herrera L. 1994. The streptokinase domain responsible for plasminogen binding. Fibrinolysis 8:276-285.
29. Shi GY, Chang BI, Chen SM, Wu DH, Wu HL. 1994. Function of streptokinase fragments in plasminogen activation. Biochem J 304:235-241.
30. Siefring GE, Castellino FJ. 1976. Interaction of streptokinase with plasminogen. J Biol Chem 251:3913-3920.
31. Teuten AJ, Broadhurst RW, Smith RAG, Dobson CM. 1993. Characterization of structural and folding properties of streptokinase by N.M.R. spectroscopy. Biochem J 290:313-319.
32. Welfle K, Pfeil W, Misselwitz R, Welfle M, Gerlach D. 1992. Conformational properties of streptokinase-differential scanning colorimetric investigations. Int J Biol Macromol 14:19-22.
33. Wohl RC. 1984. Interference of active site specific reagents in plasminogen-streptokinase active site formation. Biochemistry 23:3799-3804.
34. Wohl RC, Summaria L, Robbins KC. 1980. Kinetics of activation of human plasminogen by different activator species at pH 7.4 and 37°C. J Biol Chem 255:2005-2013.
35. Young KC, Shi GY, Chang YF, Chang BI, Chang LC, Lai MD, Chuang WJ, Wu HL. 1995. Interaction of streptokinase and plasminogen studied with truncated streptokinase peptides. J Biol Chem 270:29601-29606.