A polymer-enlarged homogeneously soluble oxazaborolidine catalyst for the asymmetric reduction of ketones by borane

Tetrahedron Asymmetry

Volumn 8, Issue 12, 1997, Pages 1975-1977

  Felder, Marcel ^a   Giffels, Guido ^a   Wandrey, Christian ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; BORANE DERIVATIVE; KETONE DERIVATIVE; REDUCING AGENT;

ARTICLE; CATALYSIS; DEGRADATION; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS;

EID: 0030924999     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(97)00192-4     Document Type: Article

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29. 2 complex (0.12 ml, 1.0 mmol) followed by a solution of 1.0 mmol of the ketone in 1 ml of anhydrous THF. After the addition, the mixture was stirred for 30 min at r.t. The reaction was then quenched with 5 ml of MeOH. Normal workup provided the crude product which could be further purified by either flash chromatography on silica gel or distillation under reduced pressure.