Endothelin expression in ocular tissues of diabetic and insulin-treated rats

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 10, 1997, Pages 2144-2151

  Chakravarthy, Usha ^a   Hayes, Ruth G ^a   Stitt, Alan W ^a   Douglas, Alasdair ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b AGRI FOOD AND BIOSCIENCES INSTITUTE   (United Kingdom)

Author keywords

Endothelin 1; Endothelin 3; Insulin; Radioimmunoassay; Streptozotocin diabetes

Indexed keywords

BIPHASIC INSULIN; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN 3; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; INSULIN TREATMENT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; RETINA; STREPTOZOCIN DIABETES;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENDOTHELIN-1; ENDOTHELIN-3; INSULIN; INTESTINE, SMALL; KIDNEY; MALE; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RETINA; RETINAL VESSELS;

EID: 0030924526     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Inoue A, Yanagisawa M, Kimura S et. al. The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA. 1989;86:2863-2867.
2. Hosoda K, Nakao K, Tamura N, et. al. Organisation, structure, chromosomal assignment and expression of the gene encoding the human endothelin-A receptor. J Biol Chem. 1992;267:18797-18804.
3. Takahashi K, Ghatei M, Jones PM, et al. Endothelin in human brain and pituitary gland. Presence of immunoreactive endothelin, endothelin messenger ribonucleic acid and endothelin receptors. J Clin Endocrinol Metab. 1991;72:693-699.
4. Lee IM, de la Monte SN, Ng SC, Bloch KD, Quertermous T. Expression of the potent vasoconstrictor endothelin in the human central nervous system. J Clin Invest. 1990;86:141-147.
5. MacCumber MW, Jampel HD, Snyder SH. Ocular effects of the endothelins. Abundant peptides in the eye. Arch Ophthalmol. 1991;109:705-709.
6. de Juan JA, Moya FJ, de Lacoba G, Cruz F, Fernandez-Durango-R. Identification and characterization of endothelin receptor subtype B in rat retina. J Neurochem. 1993;61:1113-1119.
7. MacCumber MW, Danna SA. Endothelin receptorbinding subtypes in human retina and choroid. Arch Ophthalmol. 1994;112:1231-1235.
8. Battistini B, D'Orleans-Juste P, Sirois P. Endothelins: Circulating plasma levels and presence in other biologic fluids. Lab Invest. 1993;68:600-628.
9. MacCumber NW, Ross CA, Glaser B, Snyder SH. Endothelin: Visualisation of mRNA by in-situ hybridisation provides evidence for local action. Proc Natl Acad Sci USA. 1989;86:7285-7289.
10. Schichiri M, Hirata Y, Ando K, et al. Plasma endothelin levels in hypertension and chronic renal failure. Hypertension. 1990;15:493-496.
11. Yamauchi T, Ohnaka K, Takayanagi R, Umeda F, Nawata H. Enhanced secretion of endothelin I by elevated glucose levels from cultured bovine aortic endothelial cells. FEBS Lett. 1990;267:16-18.
12. Hu RM, Levin ER, Frank HJL. Insulin stimulates production and secretion of endothelin from bovine endothelial cells. Diabetes. 1993;42:351-358.
13. Hirata Y, Takagi Y, Fukuda Y, Marumo F. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis. 1989;78:225-228.
14. Bobik A, Grooms A, Millar JA, Mitchell A, Grinpukel S. Growth factor activity of endothelin on vascular smooth muscle. Am J Physiol. 1990;258:C408-C415.
15. Takahashi K, Ghatei MA, Lam HC, O'Halloran DJ, Bloom SR. Elevated plasma endothelin levels in patients with diabetes mellitus. Diabetologia. 1990;33: 306-310.
16. Hirata Y, Emori T, Eguchi S, et al. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest. 1993; 91:1367-1373.
17. Sinclair SH, Grunvald JE, Riva CE. Retinal vascular autoregulation in diabetes mellitus. Ophthalmology. 1982;89:748-760.
18. Kohner EM. Diabetic retinopathy. BMJ. 1993;307: 1195-1199.
19. Chakravarthy U, McKibben B, Bailie JR, Douglas A, Archer DB. Immunoreactive endothelin distribution in human, rat and porcine eyes. Invest Ophthalmol Vis Sci. 1994;35:33-40.
20. Morris BJ. Specific activity of a radioimmunoassay tracer determined by self-displacement. Clin Chim Acta. 1976;73:213-221.
21. Kitamura K, Tanaka T, Kato J, Ogawa T, Eto T, Tanaka K. Immunoreactive endothelin in rat kidney inner medulla. Marked decrease in spontaneously hypertensive rats. Biochem Biophys Res Commun. 1989;162:38-44.
22. Takahashi K, Jones PM, Kanse SM. Endothelin in the gastrointestinal tract: Presence of endothelin-like immunoreactivity, endothelin-1 mRNA, endothelin receptors and its pharmacological effects. Gastroenterology. 1990;99:1660-1667.
23. Kern TS, Engerman RL. Arrest of glomerulopathy in diabetic dogs by improved glycemic control. Diabetologia. 1990;33(9):522-525.
24. Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977-986.
25. Hostetter TH, Troy JL, Brenner BM. Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int. 1981;19:410-415.
26. Grunvald JE, Riva CE, Sinclair SH, Brucker AJ, Petrig BL. Laser doppler velocimetry study of retinal circulation in diabetes mellitus. Arch Ophthalmol. 1986;104:991-996.
27. Sandeman D, Shore A, Tooke JE. Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N Engl J Med. 1992;327:760-764.
28. De La Rubia G, Oliver FJ, Inoguchi T, King GL. Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes. Diabetes. 1992;41:1533-1539.
29. Chakravarthy U, McGinnity A, McKillop J, Anderson P, Archer DB, Trimble ER. Altered endothelin I induced contraction and second messenger generation in bovine retinal microvascular pericytes cultured in high glucose medium. Diabetologia. 1993;37:36-42.
30. Sinzinger, H, Kaliman J, Klein, K Silberbauer, K. Vascular prostacyclin synthesis, platelet sensitivity, plasma factors and platelet function in patients with peripheral occlusion arteriopathy with and without diabetes mellitus. In: Nosoda G, Lewis I, Paoletti S, eds. Diet and Drugs in Atherosclerosis. New York: Raven Press; 1980:93-98.
31. Shin SJ, Lee YJ, Tan SR, Lai MS, Tsai JH. Decrease of renal endothelin 1 content and gene expression in diabetic rats with moderate hyperglycemia. Nephron. 1995;70:486-493.
32. Wolff SP, Jiang ZY, Hunt JV. Protein glycation and oxidative stress in diabetes mellitus and ageing. Free Radic Biol Med. 1991;10:339-352.
33. Brownlee M, Vlassara H, Cerami A. Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med. 1984;101:527-537.