Role of macrophage-colony-stimulating factor in regulating the accumulation and phenotype of tumor-associated macrophages

Cancer Immunology Immunotherapy

Volumn 44, Issue 3, 1997, Pages 165-172

  Dougherty, Shona T ^a,b   Eaves, Connie J ^b   McBride, William H ^c   Dougherty, Graeme J ^b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UCLA MEDICAL CENTER   (United States)

Author keywords

M CSF; Op op mice; Tumor associated macrophages

Indexed keywords

COLONY STIMULATING FACTOR 1; FC RECEPTOR; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; IMMUNOPEROXIDASE STAINING; MOUSE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; CELL DIFFERENTIATION; MACROPHAGE ACTIVATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; MICE, MUTANT STRAINS; MICE, SCID; NEOPLASMS, EXPERIMENTAL;

EID: 0030923891     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050369     Document Type: Article

References (52)

1. Austyn JM, Gordon S (1981) F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur J Immunol 11:805
2. Bajorin DF, Jakubowski A, Cody B (1990) Recombinant macrophage colony stimulating factor (rhM-CSF): a phase I clinical trial in patients with metastatic melanoma. Proc Am Soc Clin Oncol 9:183
3. Bajorin DF, Cheung NV, Houghton AN (1991) Macrophage colony-stimulating factor: biological effects and potential applications for cancer therapy. Blood 28:42
4. Benomar A, Ming WJ, Taraboletti G, Ghezzi P, Balotta C, Cianciolo GJ, Snyderman R, Dore JF, Mantovani A (1987) Chemotactic factor and P15E-related chemotaxis inhibitor in human melanoma cell lines with different macrophage content and tumorigenicity in nude mice. J Immunol 138:2372
5. Bottazzi B, Polentarutti N, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A (1983) Chemotactic activity for mononuclear phagocytes of culture supernatants from murine and human tumor cells: evidence for a role in the regulation of the macrophage content of neoplastic tissues. Int J Cancer 31: 55
6. Bottazzi B, Polentarutti N, Acero R, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A (1983) Regulation of the macrophage content of neoplasms by chemoattractants. Science 220:210
7. Bottazzi B, Colotta F, Sica A, Nobili N, Mantovani A (1990) Chemoattractant expressed in human sarcoma cells (tumor-derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein-1/monocyte chemotactic and activating factor (MCP-1/MCAF). Int J Cancer 45:795
8. Bottazzi B, Walter S, Govoni D, Colotta F, Mantovani A (1992) Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma. J Immunol 148:1280
9. Chikkappa G, Broxmeyer HE, Cooper S, Williams DE, Hangoc G, Greenberg ML, Waheed A, Shadduck RK (1989) Effect in vivo of multiple injections of purified and recombinant human macrophage colony-stimulating factor to mice. Cancer Res 49:3558
10. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294
11. Dorsch M, Hock H, Kunzendorf U, Diamantstein T, Blankenstein T (1993) Macrophage colony-stimulating factor gene transfer into tumor cells induces macrophage infiltration but not tumor suppression. Eur J Immunol 23:186
12. Dougherty GJ, Dougherty ST, Kay RJ, Lansdorp P, Humphries RK (1989) Identification and characterization of 114/A10, an antigen highly expressed on the surface of murine myoloid and erythroid progenitor cells and IL-3-dependent cell lines. Exp Hematol 17:877
13. Dougherty GJ, Kay RJ, Humphries RK (1989) Molecular cloning of 114/A10, a cell surface antigen containing highly conserved repeated elements, which is expressed by murine hemopoietic progenitor cells and interleukin-3-dependent cell lines. J Biol Chem 264:6509
14. Evans R (1972) Macrophages in syngeneic animal tumours. Transplantation 14:468
15. Evans R, Cullen RT (1984) In situ proliferation of intratumor macrophages. J Leukoc Biol 35:561
16. Folkman J, Klagsbrun M (1987) Angiogenic factors. Science 235:442
17. Frater-Schroder M, Risau W, Hallmann R, Gautschi P, Bohlen P (1987) Tumor-necrosis factor type α, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo. Proc Natl Acad Sci USA 84:5277
18. Gluzman Y (1981) SV40-transformed simian cells support the replication of early SV40 mutants. Cell 23:175
19. Harlow E, Lane D (1988) Antibodies. A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
20. Hattori M, Sakaki Y (1985) Dideoxy sequencing method using denatured plasmid templates. Anal Biochem 152:232
21. Ho MK, Springer TA (1982) Mac-1 antigen: quantitative expression in macrophage populations and tissues, and immunofluorescent localization in the spleen. J Immunol 128:2281
22. Hughes PFD, Thacker D, Hogge D, Sutherland HJ, Thomas TE, Lansdorp PM, Eaves CJ, Humphries RK (1992) Retroviral gene transfer into primitive normal and leukemic progenitor cells using clinically applicable procedures. J Clin Invest 89:1817
23. Kay R J, Boissy RJ, Russnak RH, Candido EPM (1986) Efficient transcription of a Caenorhabditis elegans heat shock gene pair in mouse fibroblasts is dependent on multiple promoter elements which can function bidirectionally. Mol Cell Biol 6:3134
24. Kay R, Dougherty GJ, Humphries RK (1990) Heterogeneous modifications of the 114/A10 protein of interleukin-3-dependent cells are concentrated in a highly repetitive amino-terminal domain. J Biol Chem 265:4962
25. Klagsbrun M, D'Amore PA (1991) Regulators of angiogenesis. Annu Rev Physiol 53:217
26. Ladner MB, Martin GA, Noble JA, Wittman VP, Warren MK, McGrogan M, Stanley ER (1988) cDNA cloning and expression of murine macrophage colony-stimulating factor from L929 cells. Proc Natl Acad Sci USA 85:6706
27. Leibovich SJ, Polverini PJ, Shepard HM, Wiseman DM, Shively V, Nuseir N (1987) Macrophage-induced angiogenesis is mediated by tumor-necrosis factor-α. Nature 239:630
28. Lieschke GL, Stanley E, Grail D, Hodgson G, Sinickas V, Gall JAM, Sinclair RA, Dunn AR (1994) Mice lacking both macrophage- and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteoporosis and severe lung disease. Blood 84:27
29. Mantovani A (1990) Tumor-associated macrophages. Curr Opin Immunol 2:689
30. Mantovani A, Ming WJ, Balotta C, Abdeljalil B, Bottazzi B (1986) Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor. Biochem Biophys Acta 865:59
31. Mantovani A, Bottazzi B, Colotta F, Sozzani S, Ruco L (1992) The origin and function of tumor-associated macrophages. Immunol Today 13:265-270
32. Matsushima K, Larsen CG, DuBious GC, Oppenheim JJ (1989) Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. J Exp Med 169:1485
33. McBride WH (1986) Phenotype and functions of intratumoral macrophages. Biochem Biophys Acta 865:27
34. Montrucchio G, Lupla E, Battaglia E, Passerini G, Bussolino F, Emanuelli G, Camussi G (1994) Tumor-necrosis factor α-induced anglogenesis depends upon in situ platelet-activating factor biosynthesis. J Exp Med 180:377
35. Moore K, McBride WH (1980) The activation state of macrophage subpopulations from a murine fibrosarcoma. Int J Cancer 26:609
36. Munn DH, Cheung NK (1989) Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor. Induction of efficient antibody mediated antitumor cytotoxicity not detected by isotope release assays. J Exp Med 170:511
37. Munn DH, Garnick MB, Cheung NV (1990) Effects of parenteral recombinant human macrophage colony-stimulating factor on monocyte number, phenotype, and antitumor cytotoxicity in non-human primates. Blood 75:2042
38. Nakoinz I, Ralph P (1988) Stimulation of macrophage antibody-dependent killing of tumor targets by recombinant lymphokine factors and M-CSF. Cell Immunol 116:331
39. Rollins BJ, Morrison ED, Stiles CD (1988) Cloning and expression of JE, a gene inducible by platelet derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci USA 85:3738
40. Rollins BJ, Sunday ME (1991) Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. Mol Cell Biol 11:3125
41. Sanda MG, Bolton E, Mule JJ, Rosenberg SA (1992) In vivo administration of recombinant macrophage colony-stimulating factor induces macrophage-mediated antibody-dependent cytotoxicity of tumor cells. J Immunother 12:132
42. Seed B (1987) An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature 329:840
43. Stewart CC (1983) Local proliferation of mononuclear phagocytes in tumors. J Reticuloendothel Soc 34:23
44. Tracey K, Vlassara H, Cerami A (1989) Cachectin/tumor necrosis factor. Lancet 20:1122
45. Tushinski RJ, Oliver IT, Gilbert LJ, Tynan PW, Warner JR, Stanley ER (1982) Survival of mononuclear phagocytes depends upon a lineage-specific growth factor that the differentiated cells selectively destroy. Cell 48:997
46. Van Damme J, Decock B, Lenaerts JP, Conings R, Bertini R, Mantovani A, Billiau A (1989) Identification by sequence analysis of chemotactic factors for monocytes produced by normal and transformed cells stimulated with virus, double standed RNA or cytokine. Eur J Immunol 19:2367-2373
47. Walter S, Bottazzi B, Govoni D, Colotta F, Mantovani A (1991) Macrophage infiltration and growth of sarcoma clones expression different amounts of monocyte chemotactic protein/JE. Int J Cancer 49:431
48. Wang JM, Griffin JD, Rambaldi A, Chen ZG, Mantovani A (1988) Induction of monocyte migration by recombinant macrophage colony-stimulating factor. J Immunol 141:575
49. Warren MK, Ralph P (1986) Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor and colony stimulating activity. J Immunol 137:2281
50. Wing EJ, Waheed A, Shadduck RK, Nagle LS, Stephenson K (1982) Effect of colony stimulating factor on murine macrophages. Induction of antitumor activity J Clin Invest 69:270
51. Wing EJ, Ampel NM, Waheed A, Shadduck RK (1985) Macrophage colony-stimulating factor (M-CSF) enhances the capacity of murine macrophages to secrete oxygen reduction products. J Immunol 135:2052
52. Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu JI, Leonard EJ (1989) Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med 169:1449