Gene-directed enzyme prodrug therapy: A review of enzyme/prodrug combinations

Expert Opinion on Investigational Drugs

Volumn 6, Issue 6, 1997, Pages 685-703

  Niculescu Duvaz, I ^a   Springer, C J ^a  

^a CRC Centre for Cancer Therapeutics   (United Kingdom)

Author keywords

Bystander effect; Enzyme; Gene therapy; Gene directed enzyme prodrug therapy; Prodrugs

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ACICLOVIR; ALKYLATING AGENT; ANTIMETABOLITE; ARGININE; CARBOXYPEPTIDASE G2; CLADRIBINE; CYCLOPHOSPHAMIDE; CYTARABINE; CYTOSINE DEAMINASE; DEOXYCYTIDINE KINASE; DIETHYLSTILBESTROL; FIALURIDINE; FLUCYTOSINE ARABINOSIDE; FLUOROURACIL; GANCICLOVIR; IFOSFAMIDE; NITROREDUCTASE; OXAZAPHOSPHORINE DERIVATIVE; PHOSPHORIBOSYLTRANSFERASE; PRODRUG; PURINE NUCLEOSIDE PHOSPHORYLASE; THYMIDINE KINASE; THYMIDINE PHOSPHORYLASE;

DRUG ACTIVATION; DRUG METABOLISM; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030923831     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.6.6.685     Document Type: Review

References (96)