The effects of intermittent administration of human parathyroid hormone (1-34) on streptozotocin-induced diabetic rats

Journal of Bone and Mineral Metabolism

Volumn 15, Issue 3, 1997, Pages 145-152

  Sato, Takeshi ^a   Sato, Kozo ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

Bone changes; Diabetes mellitus; Experimental osteoporosis; Human parathyroid hormone; Intermittent administration

Indexed keywords

PARATHYROID HORMONE[1-34];

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MINERAL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HORMONE ACTION; NONHUMAN; OSSIFICATION; OSTEOMETRY; OSTEOPOROSIS; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 0030923566     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02489947     Document Type: Article

References (26)

1. High WB, Capen CC, Block HE (1981) The effects of 1,25-dehydroxycholecalciferol, parathyroid hormone, and thyroxine on trabecular bone remodeling in adult dogs. Am J Pathol 105:279-287
2. Hefti E, Trechsel U, Bonjour JP, Fleish H, Schenk R (1982) Increase of whole-body calcium and skeletal mass in normal and osteoporotic adult rats treated with parathyroid hormone. Clin Sci (Lond) 62:389-396
3. Podbesek R (1983) Effects of two treatment regimens with synthetic human parathyroid hormone fragment on bone formation and the tissue balance of trabecular bone in greyhounds. Endocrinology 112:1000-1006
4. Guunes-Hey M, Hock JM (1984) Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone. Metab Bone Dis Relat Res 5:177-181
5. Inoue J (1985) Bone changes with long term administration of low dose 1-34 human PTH on adult beagles (in Japanese). Nippon Seikeigeka Gakkai Zasshi (J Jpn Orthop Assoc) 59:409-427
6. Tam CS, Heersche JNM, Murray TM, Parsons JA (1988) Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology 110:506-512
7. Hock JM, Hummert JR, Foseca J, Raisz LG (1988) Resorption is not essential for the stimulation of bone growth by h-PTH (1-34) in rats in vivo. J Bone Miner Res 4:449-458
8. Hock JM, Gera I, Foseca J, Raisz LG (1988) Human parathyroid hormone-(1-34) increases bone mass in ovariectomized and orchidectomized rats. Endocrinology 122:2899-2904
9. Hon M, Uzawa T, Morita K, Noda T, Takahashi H (1988) Effect of human parathyroid hormone (PTH(1-34)) on experimental osteopenia of rats induced by ovariectomy. Bone Miner 3:193-199
10. Liu CC, Kalu DN (1990) Human parathyroid hormone (1-34) prevents bone loss and augments bone formation in sexually mature ovariectomized rats. J Bone Miner Res 5:973-982
11. Tada K, Yamamuro T, Okumura H, Kasai R, Takahashi H (1990) Restoration of axial and appendicular bone volumes by h-PTH (1-34) in parathyroidectomized and osteopenic rats. Bone (NY) 11:163-169
12. Hodsman AB, Steer BM, Fraher LJ, Drost DJ (1991) Bone densitometric and histomorphometric responses to sequential human parathyroid hormone (1-38) and salmon calcitonin in osteoporotic patients. Bone Miner 14:67-83
13. Reeve J, Bradbeer JN, Arlot M, Davies UM, Green JR, Hampton L, Edouard C, Hasp R, Hulme P, Ashby JP, Zarelli JM, Meunier PJ (1991) h-PTH 1-34 treatment of osteoporosis with added hormone replacement therapy: biochemical, kinetic and histological response. Osteoporosis Int 1:162-170
14. Shen V, Dempster DW, Mellish RWE, Birchman R, Horbet W, Lindsay R (1992) Effects of combined and intermittent administration of low-dose human parathyroid hormone fragment (1-34) and 17β-estradiol on bone histomorphometry in ovariectomized rats with established osteopenia. Calcif Tissue Int 50:214-220
15. Wronski TJ, Yen CF, Qi H, Dann LM (1993) Parathyroid hormone is more effective than estrogen or bisphosphonates for restoration of lost bone mass in ovariectomized rats. Endocrinology 132:823-831
16. Jerome CP (1994) Anabolic effect of high doses human parathyroid hormone (1-38) in mature intact female rats. J Bone Miner Res 9:933-942
17. Sato K, Arakawa S, Tanaka Y, Tanaka Y, Suzuki K, Goto Y (1987) Bone histomorphometric study of biopsied bone in diabetic patients. J Bone Miner Metab 4:206-213
18. McNair P, Madsbad S, Christiansen C, Faber OK, Transbol I, Binder C (1978) Osteopenia in insulin treated diabetes mellitus: its relation to age at onset, sex and duration of disease. Diabetologia 15:87-90
19. Santiago JV, McAlister WH, Ratzan SK, Bussman Y, Haymond MW, Shackelford G, Weldon VV (1977) Decreased cortical thickness & osteopenia in children with diabetes mellitus. J Clin Endocrinol Metab 45:845-848
20. Hayashi Y, Yamamoto K (1989) DIP method (in Japanese). In: Morita R (ed) Measurement of bone mineral and osteoporosis. Medical Review, Tokyo, pp 43-47
21. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. J Bone Miner Res 2:595-610
22. Goodman WG, Hori MT (1984) Diminished bone formation in experimental diabetes. Relationship to osteoid maturation and mineralization. Diabetes 33:825-831
23. Glajchen N, Epstein F, Ismail F,Thomas S, Fallon M, Chakrabarti S (1988) Bone mineral metabolism in experimental diabetes mellitus: osteocalcin as a measure of bone remodeling. Endocrinology 123:290-295
24. Hough S, Avioli LV, Bergfeld MA (1981) Correction of abnormal bone and mineral metabolism in chronic streptozotocin-induced diabetes mellitus in rat by insulin therapy. Endocrinology 108: 2228-2234
25. Schneider LE, Omdahl J, Schedl HP (1976) Effects of vitamin D and its metabolites on calcium transport in the diabetic rat. Endocrinology 99:93-799
26. Spencer EM (1980) Experimental diabetes in the rat causes an insulin reversible decrease in renal 25-hydroxyvitamin D-1-hydroxylase activity. Endocrinology 107:300-304