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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
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High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia
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The 12:21 translocation involving TEL and deletion of the other TEL allele: Two frequently associated alterations found in childhood acute lymphoblastic leukemia
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TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
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Shurtleff SA, Buijs A, Behm FG, Rubnitz JE, Raimondi SC, Hancock ML, Chan GCF, Pui CH, Grozveld G, Dowing JR (1995): TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia 9:1985-1989.
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The use of the polymerase chain reaction in the detection of AML1/ETO fusion transcript in t(8;21)
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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
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The t(8;21) fusion protein interferes with AML1B dependent transcriptional activation
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Involvement of the TEL gene in hematologie malignancy by diverse molecular genetic mechanisms
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