Immunophenotype of Reed-Sternberg and Hodgkin's cells in sequential biopsy specimens of Hodgkin's disease: A paraffin-section immunohistochemical study using the heat-induced epitope retrieval method

American Journal of Clinical Pathology

Volumn 108, Issue 1, 1997, Pages 54-59

  Vasef, Mohammad A ^a   Alsabeh, Randa ^a   Medeiros, L Jeffrey ^a   Weiss, Lawrence M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

CD15; CD30; Heat induced epitope retrieval; Hodgkin's disease; Immunohistochemistry; Reed Sternberg cells

Indexed keywords

CD15 ANTIGEN; CD20 ANTIGEN; CD30 ANTIGEN; EPITOPE;

ADOLESCENT; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; BIOPSY; CLINICAL ARTICLE; FEMALE; HISTOLOGY; HODGKIN DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INFLAMMATORY CELL; MALE; PRIORITY JOURNAL; REED STERNBERG CELL; SCHOOL CHILD;

EID: 0030923344     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/108.1.54     Document Type: Article

References (24)

1. Chittal SM, Caveriviere P, Schwarting R, et al. Monoclonal antibodies in the diagnosis of Hodgkin's disease: the search for a rational panel. Am J Surg Pathol. 1988;12:9-21.
2. Dorfman RF, Gatter KC, Pulford KA, Mason DY. An evaluation of the utility of anti-granulocyte and anti-leukocyte monoclonal antibodies in the diagnosis of Hodgkin's disease. Am J Pathol 1986;123:508-519.
3. Hall PA, D'Ardenne AJ, Stansfeld AG. Paraffin section immunohistochemistry, II: Hodgkin's disease and large cell anaplastic (Ki-1) lymphoma. Histopathology. 1988;13:161-169.
4. Hsu SM, Jaffe ES. Leu M1 and peanut agglutinin stain the neoplastic cells of Hodgkin's disease. Am J Clin Pathol. 1984;82:29-32.
5. Medeiros LJ, Weiss LM, Warnke RA, Dorfman RA. Utility of combining anti-granulocyte and anti-leukocyte antibodies in differentiating Hodgkin's disease from non-Hodgkin's lymphoma. Cancer. 1988;62:2475-2481.
6. Perkins SL, Kjeldsberg CR. Immunophenotyping of lymphomas and leukemias in paraffin-embedded tissues. Am J Clin Pathol. 1993;99:362-373.
7. Schmid C, Sargent C, Isaacson PG. L and H cells of nodular lymphocyte predominant Hodgkin's disease show immunoglobulin light-chain restriction. Am J Pathol. 1991;139:1281-1289.
8. Stoler MH, Nichols GE, Symbula M, Weiss LM. Lymphocyte predominance Hodgkin's disease: evidence for a κ light chain-restricted monotypic B-cell neoplasm. Am J Pathol. 1995;146:812-818.
9. Korkolopoulou P, Cordell J, Jones M, et al. The expression of the B-cell marker mb-1 (CD79a) in Hodgkin's disease. Histopathology. 1994;24:511-515.
10. Schmid C, Pan L, Diss T, Isaacson PG. Expression of B-cell antigens by Hodgkin's and Reed-Sternberg cells. Am J Pathol. 1991;139:701-707.
11. Siebert JD, McClure SP, Banks PM, Gulley ML. Hodgkin's disease, mixed cellularity type, with a B-cell immunophenotype: report of a case and literature review. Arch Pathol Lab Med. 1995;119:474-479.
12. Zukerberg LR, Collins AB, Ferry JA, Harris NL. Coexpression of CD15 and CD20 by Reed-Sternberg cells in Hodgkin's disease. Am J Pathol. 1991;139:475-483.
13. Weiss LM, Chen Y-Y, Liu X-F, Shibata D. Epstein-Barr virus and Hodgkin's disease: a correlative in situ hybridization and polymerase chain reaction study. Am J Pathol. 1991;139:1259-1265.
14. Chu WS, Abbondanzo SL, Frizzera G. Inconsistency of the immunophenotype of Reed-Sternberg cells in simultaneous and consecutive specimens from the same patients: a paraffin section evaluation in 56 patients. Am J Pathol. 1992;141:11-17.
15. Battifora H, Alsabeh R, Jenkins KA, Gown A. Epitope retrieval (unmasking) in immunohistochemistry. Adv Pathol Lab Med. 1995;8:101-118.
16. Huang SN, Minassian H, Moore JD. Application of immunofluorescent staining on paraffin sections improved by trypsin digestion. Lab Invest. 1976;35:383-390.
17. Momose H, Mehta P, Battifora H. Antigen retrieval by microwave irradiation in lead thiocyanate: a comparison with protease digestion retrieval. Appl Immunohistochem. 1993;1:77-82.
18. Pasha T, Montone KT, Tomaszewski JE. Nuclear antigen retrieval utilizing steam heat. Mod Pathol. 1995;8:167. Abstract.
19. Shi SR, Key ME, Kalra KL. Antigen retrieval in formalin-fixed paraffin-embedded tissues: an enhancement method for immunohistochemical staining bases on microwave oven heating of tissue sections. J Histochem Cytochem. 1991;39:741-748.
20. Chang KL, Kamel OW, Arber DA, Horyd ID, Weiss LM. Pathologic features of nodular lymphocyte predominance Hodgkin's disease in extranodal sites. Am J Surg Pathol. 1995;19:1313-1324.
21. Regula DP Jr, Weiss LM, Warnke RA, Dorfman RF. Lymphocyte predominance Hodgkin's disease: a reappraisal based upon histological and immunophenotypical findings in relapsing cases. Histopathology. 1987;11:1107-1120.
22. Sheibani K, Tubbs RR. Enzyme immunohistochemistry: technical aspects. Semin Diagn Pathol. 1984;1:235-250.
23. Arber JM, Arber DA, Jenkins KA, Battifora H. Effect of decalcification and fixation in paraffin-section immunohistochemistry. Appl Immunohistochem. 1996;4:241-248.
24. Agnarsson BA, Kadin ME. The immunophenotype of Reed-Sternberg cells: a study of 50 cases of Hodgkin's disease using fixed frozen tissues. Cancer. 1989;63:2083-2087.