A new breakpoint, telomeric to TEL/ETV6, on the short arm of chromosome 12 in T cell acute lymphoblastic leukemia

Leukemia

Volumn 11, Issue 8, 1997, Pages 1360-1363

  Le Coniat, M ^a   Della Valle, V ^a   Marynen, P ^b   Berger, R ^a  

^a INSERM   (France)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

12p; T cell ALL; TEL ETV6

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CENTROMERE; CHROMOSOME 12P; CHROMOSOME BREAKAGE; CHROMOSOME TRANSLOCATION 12; CHROMOSOME TRANSLOCATION 14; CHROMOSOME TRANSLOCATION 7; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; T CELL LEUKEMIA; TELOMERE;

EID: 0030922870     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400737     Document Type: Article

References (14)

1. Mitelman F. Catalog of Chromosome Aberrations in Cancer, 5th edn. Wiley-Liss: New York, 1994.
2. Golub TR, Barker CF, Lovett M, Gilliland DC. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 1994; 77: 307-316.
3. Bernard OA, Romana SP, Poirel H, Berger R. Molecular cytogenetics of t(12;21)(p13;q22). Leuk Lymphoma 1996; 23: 459-465.
4. Romana SP, LeConiat M, Berger R, t(12;21): a new recurrent translocation in acute lymphoblastic leukemia. Genes Chromosom Cancer 1994; 9: 186-191.
5. Baens M, Peeters P, Guo C, Aerssens J, Marynen P. Genomic organization of TEL: the human ETS-variant gene 6. Genome Res 1996; 6: 404-113.
6. Aerssens J, Guo C, Vermeesch J, Baens M, Browne D, Litt M, Van Den Berghe H, Marynen P. A physical map of the region spanning the chromosome 12 translocation breakpoint in a mesothelioma with a t(X;12)(q22;p13). Cytogenet Cell Genet 1995; 71: 268-275.
7. Sambrook J, Fritsch E, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory: Cold Spring Harbor, 1989.
8. Bernard O, Guglielmi P, Jonveaux P, Cherif D, Gisselbrecht S, Mauchauffé M, Larsen C-J, Berger R, Mathieu-Mahul D. Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemia. Genes Chromosom Cancer 1990; 1: 194-208.
9. Raynaud S, Cavé H, Baens M, Bastard C, Cacheux V, Grosgeorge J, Guidal-Giroux C, Guo C, Vilmer E, Marynen P, Granchamp B. The t(12;21) translocation involving TEL and deletion of the other allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia. Blood 1996; 87: 2891-2899.
10. Sato Y, Suto Y, Pietenpol J, Golub TT, Gilliland DC, Davis EM, Le Beau MM, Roberts JM, Vogelstein B, Rowley JD, Bohlander SK. TE1 and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies. Blood 1995; 86: 1525-1533.
11. Stegmaier K, Pendse S, Barker GF, Bray-Ward P, Ward DC, Montgomery KT, Krauter KS, Reynolds C, Sklar J, Donnelly M, Bohlander SK, Rowley JD, Sallan SE, Gilliland DC, Golub TR. Fre-quent loss of heterozygosity at the TEL gene locus in acute leukemia of childhood. Blood 1995; 86: 38-44.
12. Heim S, Békassy AN, Garwicz S, Helsdrup J, Wiebe T, Kristoffersson U, Mandhal N, Mitelman F. New structural chromosomal rearrangements in congenital leukemia. Leukemia 1987; 1: 16-23.
13. Pui C-H, Carroll AJ, Raimondi SC, Schell MJ, Head DR, Shuster JJ, Crist WM, Borowitz MJ, Link MP, Behm FC, Steuber CP, Land VJ. Isochromosomes in childhood acute lymphoblastic leukemia: a collaborative study of 83 cases. Blood 1992; 79: 2384-2391.
14. O'Connor H, Clark R, Swanton S, Secker Walker LM, Foroni L. The site of the TEI/ETV6 gene in 12P12-13 is frequently involved in patients carrying a variety of 12P chromosomal abnormalities: a combined PCR and Southern analysis. Blood 1996; 88 (Suppl.1): 65a.