Induction of heat-shock protein (HSP72) in the cingulate and retrosplenial cortex by drugs that antagonize the effects of excitatory amino acids

Molecular Brain Research

Volumn 46, Issue 1-2, 1997, Pages 297-302

  Lan, J Q ^a,c   Chen, J ^a   Sharp, F R ^b   Simon, R P ^a   Graham, S H ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c INSTITUTE OF SPACE MEDICO ENGINEERING   (China)

Author keywords

AMPA; Excitatory amino acid; Heat shock protein; N methyl D aspartate (NMDA); Toxicity; Vacuole

Indexed keywords

EXCITATORY AMINO ACID; GLUTAMATE RECEPTOR ANTAGONIST; HEAT SHOCK PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ADRENALECTOMY; ARTICLE; CELL VACUOLE; CINGULATE GYRUS; IMMUNOCYTOCHEMISTRY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION;

ANIMALS; CEREBRAL CORTEX; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GYRUS CINGULI; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; MALE; PIPECOLIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030922622     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00003-X     Document Type: Article

References (34)

1. Auer, R.N., Jason, G.W., Trammer, B.I. and Copeland, S., Effect of MK801 in focal ischemia in the monkey, Soc. Neurosci. Abstr., 20 (1994) 1061. [Abstract.]
2. Benveniste, H., Drejer, J., Schousboe, A. and Diemer, N.H., Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis, J. Neurochem., 43 (1984) 1369-1374.
3. Berger, P., Farrel, K., Sharp, F. and Skolnick, P., Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex, Neurosci. Lett., 168 (1994) 147-150.
4. Brown, I.R., Rush, S. and Ivy, G.O., Induction of a heat shock gene at the site of tissue injury in the rat brain, Neuron, 2 (1989) 1559-1564.
5. Chen, J., Graham, S., Moroni, F. and Simon, R., A study of the dose dependency of a glycine receptor antagonist in focal ischemia, J. Pharmacol. Exp. Ther., 267 (1993) 937-941.
6. Choi, D.W., Glutamate neurotoxicity and diseases of the nervous system, Neuron, 1 (1988) 623-634.
7. Faden, A.I., Lemke, M., Simon, R.P. and Noble, L.J., N-Methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, and neurochemical studies, J. Neurotrauma, 5 (1988) 33-45.
8. Fix, A.S., Horn, J.W., Wightman, K.A., Johnson, C.A., Long, G.G., Storts, R.W. et al., Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK( + )801 (dizocilpine maleate): a light and electron microscopic evaluation of the rat retrosplenial cortex, Exp. Neurol., 123 (1993) 204-215.
9. Glazier, S.S., O'Rourke, D.M., Graham, D.I. and Welsh, F.A., Induction of ischemic tolerance following brief focal ischemia in rat brain, J. Cereb. Blood Flow Metab., 14 (1994) 545-553.
10. Gonzalez, M.F., Shiraishi, K., Hisanaga, K., Sagar, S.M., Mandabach, M. and Sharp, F.R., Heat shock proteins as markers of neural injury, Mol. Brain Res., 6 (1989) 93-100.
11. Graham, S.H., Chen, J., J.Q., L., Leach, M.J. and Simon, R.P., Neuroprotective effects of a voltage dependent sodium channel antagonist BW619C89 in rat middle cerebral artery occlusion, J. Pharmacol. Exp. Ther., 269 (1994) 854-859.
12. Graham, S.H., Chen, J., Lan, J., Leach, M.J. and Simon, R.P., Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion, J. Pharmacol. Exp. Ther., 269 (1994) 854-859.
13. Graham, S.H., Chen, J., Lan, J.Q. and Simon, R.P., A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia, J. Pharmacol. Exp. Ther., 276 (1996) 1-4.
14. Greenamyre, J.T., Eller, R.V., Zhang, Z., Ovadia, A., Kurlan, R. and Gash, D.M., Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease, Ann. Neurol., 35 (1994) 655-661.
15. Halliwell, R.F., Peters, J.A. and Lambert, J.J., The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture, Br. J. Pharmacol., 96 (1989) 480-494.
16. Hasegawa, Y., Fisher, M., Baron, B.M. and Metcalf, G., The competitive NMDA antagonist MDL-100,453 reduces infarct size after experimental stroke, Stroke, 25 (1994) 1241-1244.
17. Lipton, S.A. and Rosenberg, P.A., Excitatory amino acids as a final common pathway for neurologic disorders, N. Engl. J. Med., 330 (1994) 613-622.
18. McIntosh, T.K., Neurochemical sequelae of traumatic brain injury: therapeutic implications, Cerebrovasc. Brain Metab. Rev., 6 (1994) 109-162.
19. Muir, K.W. and Lees, K.R., Clinical experience with excitatory amino acid antagonist drugs, Stroke, 26 (1995) 503-513.
20. Nakki, R., Koistinaho, J., Sharp, F.R. and Sagar, S.M., Cerebellar toxicity of phencyclidine, J. Neurosci., 15 (1995) 2097-2108.
21. Olney, J.W., Labruyere, J. and Price, M.T., Pathological changes induced in cerebrocortical neurons by phenyyclidine and related drugs, Science, 244 (1989) 1360-1362.
22. Rothstein, J.D., Martin, L.J. and Kuncl, R.W., Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis, N. Engl. J. Med., 326 (1992) 1464-1468.
23. Sharp, F.R., Butman, M., Koistinaho, J., Aardalen, K., Nakki, R., Massa, S.M. et al., Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via multiple receptors and voltage gated calcium channels, Neuroscience, 62 (1994) 1079-1092.
24. Sharp, F.R., Butman, M., Wang, S., Koistinaho, J., Graham, S.H., Sagar, S.M. et al., Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine, J. Neurosci. Res., 33 (1992) 605-616.
25. Sharp, F.R., Jasper, P., Hall, J., Noble, L. and Sagar, S.M., MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex, Ann. Neurol., 30 (1991) 801-809.
26. Sharp, F.R., Lowenstein, D., Simon, R. and Hisanaga, K., Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction, J. Cereb. Blood Flow Metab., 11 (1991) 621-627.
27. Sheardown, M.J., Nielsen, E.Ø., Hansen, A.J., Jacobsen, P. and Honore, T., 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia, Science, 247 (1990) 571-574.
28. Simon, R.P., Swan, J.H., Griffiths, T. and Meldrum, B.S., Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain, Science, 226 (1984) 850-852.
29. Sonders, M.S., Keana, J.F. and Weber, E., Phencyclidine and psychotomimetic sigma opiates: recent insights into their biochemical and physiological sites of action, Trends Neurosci., 11 (1988) 37-40.
30. Thomson, A.M., Glycine modulation of the NMDA receptor/channel complex, Trends Neurosci., 12 (1989) 349-353.
31. Vass, K., Berger, M.L., Nowak, Jr., T., Welch, W.J. and Lassmann, H., Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat, Neurosci. Lett., 100 (1989) 259-264.
32. Wu, C., Wilson, S., Walker, B., Dawid, I., Paisley, T., Zimarino, V. et al., Purification and properties of Drosophila heat shock activator protein, Science, 238 (1987) 1247-1253.
33. Xiao, H. and Lis, J.T., Germline transformation used to define key features of heat-shock response elements, Science, 239 (1988) 1139-1142.
34. Zimarino, V., Tsai, C. and Wu, C., Complex modes of heat shock factor activation, Mol. Cell Biol., 10 (1990) 752-759.