The action of local anesthetics on myelin structure and nerve conduction in toad sciatic nerve

Biophysical Journal

Volumn 72, Issue 6, 1997, Pages 2581-2587

  Mateu, Leonardo ^a,c   Morán, Oscar ^a,d   Padrón, Raúl ^a   Borgo, María ^a   Vonasek, Eva ^a   Márquez, Gustavo ^a   Luzzati, Vittorio ^b  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b CNRS   (France)

^c Bamco CCS 199 00 ^*  (United States)

^d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CINCHOCAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MYELIN; PROCAINE; RINGER SOLUTION; TETRACAINE;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; DENSITY; DRUG MECHANISM; ELECTROPHYSIOLOGY; NERVE CONDUCTION; NONHUMAN; RADIATION SCATTERING; SCIATIC NERVE; TOAD;

EID: 0030922367     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78901-X     Document Type: Article

References (28)

1. Blaurock, A. E. 1971. Structure of the nerve myelin membrane: proof of the low resolution profile. J. Mol. Biol. 56:35-52.
2. Blaurock, A. E. 1982. Evidence of bilayer structure and of membrane interactions from x-ray diffraction analysis. Biochim. Biophys. Acta. 650:167-207.
3. Blaustein, M. P., and D. Goldman. 1966. Action of anionic and cationic nerve-blocking agents: experiments and interpretation. Science. 153: 429-432.
4. Caspar, D. L. D., and D. A. Kirschner. 1971. Myelin membrane structure at 10 Å resolution. Nature New Biol. 231:46-52.
5. Edström, A., and M. Kanje. 1988. Regeneration in-vitro of the adult frog sciatic nerve. Neurosci. Lett. 90:113-118.
6. Franks, N. P., and W. R. Lieb. 1994. Molecular and cellular mechanisms of general anesthesia. Nature. 367:607-614.
7. Freud, S. 1884. Centralblat. Ges. Ther. 2:289-314.
8. Gabriel, A. 1979. A position sensitive x-ray detector. Rev. Sci. Instrum. 48:1303-1305.
9. Guo, X., N. A. Castle, D. M. Chernoff, and G. R. Strichart. 1991. Comparative inhibition of voltage-gated cation channels by local anesthetics. Ann. N.Y. Acad. Sci. 625:181-199.
10. Hille, B. 1980. Theories of anesthesia: general perturbations versus specific receptors. Prog. Anaesthesiol. 2:1-5.
11. Lee, A. G. 1976. Model for action of local anesthetics. Nature. 262: 545-548.
12. Luzzati, V., and L. Mateu. 1990. Order-disorder phenomena in myelinated nerve sheaths. I. A physical model and its parametrization: exact and approximate determination of the parameters. J. Mol. Biol. 215:373-384.
13. Mateu, L., V. Luzzati, M. Borgo, E. Vonasek, and R. Vargas. 1991. Order-disorder phenomena in myelinated nerve sheaths. III. The structure of myelin in rat optic nerves over the course of myelinogenesis. J. Mol. Biol. 220:351-357.
14. Mateu, L., V. Luzzati, G. M. Villegas, M. Borgo, and R. Vargas. 1992. Order-disorder phenomena in myelinated nerve sheaths. IV. The disordering effect of high levels of local anesthetics on rat sciatic and optic nerves. J. Mol. Biol. 226:535-548.
15. Mateu, L., V. Luzzati, E. Vonasek, E. Mateu, G. M. Villegas, and R. Vargas. 1995. Order-disorder phenomena in myelinated nerve sheaths. V. Effects of temperature on rat sciatic and optic nerves and structural differences between the two types of nerve. J. Mol. Biol. 245:110-125.
16. Mateu, L., V. Luzzati, E. Vonasek, M. Borgo, and F. Lachapelle. 1996. Order-disorder phenomena in myelinated nerve sheaths. VI. The effects of quacking, jimpy and shiverer mutations: an x-ray scattering study of mouse sciatic and optic nerves. J. Mol. Biol. 256:319-329.
17. Mateu, L., and O. Morán. 1986. Reversible changes in myelin structure and electrical activity during anesthesia in vivo. Biochim. Biophys. Acta. 862:17-26
18. Morán, O. 1984. Alteración de la estructura molecular de la mielina en condiciones casi fisiológicas. Ph.Sc. thesis. Centro de Estudios Avanzados, IVIC, Caracas, Venezuela.
19. Padrón, R., and L. Mateu. 1980. The effect of the repetitive propagation of action potentials on the structure of toad sciatic nerve myelin membranes: an x-ray diffraction study at 11 Å resolution. J. Neurosci. Res. 5:611-620.
20. Padrón, R., and L. Mateu. 1981. In vivo structure of frog sciatic nerve myelin membranes: an x-ray diffraction study at 13 Å resolution. J. Neurosci. Res. 6:251-260.
21. Padrón, R., L. Mateu, and J. Requena. 1979. A dynamic x-ray diffraction study of anesthesia action. Thickening of the myelin membrane by n-pentane. Biochim. Biophys. Acta. 552:535-539.
22. Padrón, R., L. Mateu, and J. Requena. 1980. A dynamic x-ray diffraction of anesthesia action. Changes in myelin structure and electrical activity recorded simultaneously from frog sciatic nerves treated with n-alkanes. Biochim. Biophys. Acta. 602:221-233.
23. Ritchie, J. M., and N. M. Greene. 1985. Local anesthetics. In The Pharmacological Basis of Therapeutics. A. Goodman, L. S. Goodman, T. W. Rall, and F. Mervad, editors. Macmillan Publishing Co., New York.
24. Rud, J. 1961. Local anesthetics: an electrophysiological investigation of local anesthesia of peripheral nerves, with special reference to xilocaline. Acta Physiol. Scand. 51(Suppl):17-25.
25. Seeman, P. 1972. Membrane actions of anesthetics and tranquilizers. Pharmacol. Rev. 24:583-655.
26. Strichart, G. R. 1975. Inhibition of ionic currents in myelinated nerves by quaternary derivatives of lidocaine. In Molecular Mechanisms of Anesthesia. B. R. Fink, editor. Raven Press, New York. 1-11.
27. Strichart, G. R. 1976. Molecular mechanisms of nerve block by local anesthetics. Anesthesiology. 45:421-441.
28. Tedeschi, B., and F. J. Liuzzi. 1992. Axotomized frog sciatic nerves releases diffusible neurite-promoting factors. Dev. Brain Res. 69: 97-107.