Functional magnesium deficiency in critically ill patients identified using a magnesium-loading test

Critical Care Medicine

Volumn 25, Issue 5, 1997, Pages 749-755

  Hébert, Paul ^a   Mehta, Nav ^a   Wang, Jian ^a   Hindmarsh, Thomas ^a   Jones, Gwynne ^a   Cardinal, Pierre ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Critical care; Electrolyte abnormality; Hypomagnesemia; Ionized magnesium; Laboratory tests; Magnesium; Magnesium deficiency; Magnesium loading test; Serum assays; Serum magnesium

Indexed keywords

BIOCHEMICAL MARKER; CALCIUM; CREATININE; GLUCOSE; MAGNESIUM; MAGNESIUM SULFATE; PHOSPHATE; POTASSIUM; SODIUM; SODIUM CHLORIDE;

ADULT; AGED; ARTICLE; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRITICAL ILLNESS; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HYPOMAGNESEMIA; INTRAVENOUS DRUG ADMINISTRATION; LOADING TEST; MAGNESIUM BLOOD LEVEL; MAGNESIUM DEFICIENCY; MAGNESIUM URINE LEVEL; MALE; POTASSIUM BLOOD LEVEL; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SODIUM BLOOD LEVEL;

AGED; APACHE; CRITICAL CARE; CRITICAL ILLNESS; DOUBLE-BLIND METHOD; ELECTROLYTES; FEASIBILITY STUDIES; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MAGNESIUM DEFICIENCY; MAGNESIUM SULFATE; MALE; MIDDLE AGED;

EID: 0030922315     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199705000-00007     Document Type: Article

References (26)

1. Wong ET, Rude RK, Singer FR, et al: A high prevalence of hypomagnesaemia and hypermagnesemia in hospitalized patients. Am J Clin Pathol 1983; 79: 348-352
2. Ryzen E, Wagers PW, Singer FR, et al: Magnesium deficiency in a medical ICU population. Crit Care Med 1985; 13: 19-21
3. Reinhart RA: Hypomagnesaemia in patients entering the ICU. Crit Care Med 1985; 13:506-507
4. Rubeiz GJ, Thill-Baharozian M, Hardie D, et al: Association of hypomagnesemia and mortality in acutely ill medical patients. Crit Care Med 1993; 21: 203-209
5. Laban E, Charbon GA: Magnesium and cardiac arrhythmias: Nutrient or drug? J Am Coll Nutr 1986; 5:512-532
6. Leary WP, Reyes AJ, Lockett CJ, et al: Magnesium and deaths ascribed to ischaemic heart disease in South Africa. S Afr Med J 1983; 64:775-776
7. Rylander R, Bonevik H, Rubinoviz E: Magnesium and calcium in drinking water and cardiovascular mortality. Scand J Work Environ Health 1991; 17:91-94
8. Zaloga GP, Wilkens R, Tourville J, et al: A simple method for determining physiologically active calcium and magnesium concentration in critically ill patients. Crit Care Med 1987; 15: 813-816
9. Kingston ME, Al-Sibai MB, Skooge WC: Clinical manifestations of hypomagnesium. Crit Care Med 1986; 14: 950-954
10. Whang R: Routine serum magnesium determination: A continuing unrecognized need. Magnesium 1987; 6:1-4
11. Elin RJ: Status of the mononuclear blood cell magnesium assay. J Am Coll Nutr 1987; 6:105-107
12. Zaloga GP: Interpretation of the serum magnesium level. Chest 1989; 95: 257-258
13. Reinhart RA: Magnesium metabolism. Arch Intern Med 1988; 148:2415-2420
14. Maj-Zurawska M, Lewenstam A: Fully automated potentiometric determination of ionized magnesium in blood serum. Analytical Chimica Acta 1990; 236:331-335
15. Raju B, Murphy E, Levy LA, et al: A fluorescent indicator for measuring cytosolic free magnesium. Am J Physiol 1989; 256:C540-C548
16. Quamme GA: Laboratory evaluation of Mg status. Renal function and free intercellular magnesium concentration. Clin Lab Med 1993; 13:209-223
17. Ryzen E, Elbaum N, Singer FR, et al: Parenteral magnesium tolerance testing in the evaluation of magnesium deficiency. Magnesium 1985; 4:137-147
18. Chernow B, Bamberger S, Stoiko M, et al: Hypomagnesemia in patients in postoperative intensive care. Chest 1989; 95:391-397
19. Dyckner T, Wester PO: The relation between extra- and intracellular electrolytes in patients with hypokalemia and/or diuretic treatment. Acta Med Scand 1978; 204:269-282
20. Caddell JL, Saier FL, Thomason CA: Parenteral magnesium load tests in postpartum American women. Am J Clin Nutr 1975; 28:1099-1104
21. LaSala M, Lifshitz F, Silverberg M, et al: Magnesium metabolism studies in children with chronic inflammatory disease of the bowel. J Pediatr Gastroenterol Nutr 1985; 4:75-81
22. Caddell JL, Goddard PR: Studies in protein-calorie malnutrition. N Engl J Med 1967; 276:533-535
23. Dyckner T, Wester PO: Renal excretion of electrolytes in patients on long-term diuretic therapy for arterial hypertension and/or congestive heart failure. Acta Med Scand 1985; 218: 443-448
24. Quamme G, Dirks J: The physiology of renal magnesium handling. Renal Physiol 1986; 9:257-269
25. Greenway DC, Hindmarsh JT, Wang J, et al: Reference interval of whole blood ionized magnesium in a healthy population and the stability of ionized magnesium under different laboratory conditions. Clin Biochem 1996; 29:515-520
26. Wacker WEC, Parisi AF: Magnesium metabolism. N Engl J Med 1968; 278: 658-663