Usefulness of DNA viral load quantification for cytomegalovirus disease monitoring in renal and pancreas/renal transplant recipients

Transplantation

Volumn 63, Issue 10, 1997, Pages 1476-1481

  Imbert Marcille, Berthe Marie ^a   Cantarovich, Diego ^a   Ferre Aubineau, Virginie ^a   Richet, Béatrice ^a   Soulillou, Jean Paul ^a   Billaudel, Sylviane ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ALANINE AMINOTRANSFERASE; AMYLASE; AZATHIOPRINE; CYCLOSPORIN A; GANCICLOVIR; IMMUNOSUPPRESSIVE AGENT; LIVER ENZYME; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 4; PEPTIDE; PREDNISOLONE; STEROID; THYMOCYTE ANTIBODY; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DNA VIRUS; FEMALE; GRAFT REJECTION; HUMAN; HYBRIDIZATION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; MALE; PANCREAS; PANCREAS TRANSPLANTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECIPIENT; SEROLOGY; VIRUS GENOME;

ADOLESCENT; ADULT; AGED; ANTIVIRAL AGENTS; BIOLOGICAL MARKERS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; FEMALE; FOLLOW-UP STUDIES; GANCICLOVIR; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; PREVALENCE; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS;

EID: 0030922224     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199705270-00018     Document Type: Article

References (23)

1. Cantarovich D, Baatard R, Baranger et al. Cadaveric renal transplantation after 60 years of age: a single center experience. Transpl Int 1994; 7: 33.
2. Boeckh M, Woogerd PM, Stevens-Ayers T, Ray CG, Bowden RA. Factors influencing detection of quantitative cytomegalovirus antigenemia. J Clin Microbiol 1994; 32: 832.
3. Van den Berg AP, Van der Bij W, Van Son WJ et al. Cytomegalovirus antigenemia as a useful marker of symptomatic cytomegalovirus infection after renal tranplantation: a report of 130 consecutive patients. Transplantation 1989; 48: 991.
4. The TH, van der Ploeg M, van den Berg AP, et al. Direct detection of cytomegalovirus in peripheral blood leukocytes: a review of the antigenemia assay and polymerase chain reaction. Transplantation 1992; 54: 193.
5. Saltzman RL, Quirk MR, Jordan MC. High levels of circulating cytomegalovirus DNA reflect visceral organ disease in viremic immunosuppressed patients other than marrow recipients. J Clin Invest 1992; 90: 1832.
6. Kühn JE, Wendland T, Schäfer P, et al. Monitoring of renal allograft recipients by quantitation of human cytomegalovirus genomes in peripheral blood leukocytes. J Med Virol 1994; 44: 398.
7. Imbert-Marcille BM, Milpied N, Coste-Burel M, et al. Clinical and practical value of human cytomegalovirus DNAemia detection by semi-nested PCR, for BMT recipients' follow-up. Bone Marrow Transplant 1995; 15: 611.
8. Griffiths PD, Stirk PR, Ganczakowski M, et al. Rapid diagnosis of cytomegalovirus infection in immunocompromised patients by detection of early antigen fluorescent foci. Lancet 1984; 2: 1242.
9. Saïki RK, Gelfand DH, Stoffel S, et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988; 239: 487.
10. Poirier-Toulemonde AS, Imbert-Marcille BM, Ferré-Aubineau V, et al. Successful quantification of cytomegalovirus DNA by competitive PCR and capillary electrophoresis. Mol Cell Probes 1997; 11: 11.
11. Mazzuli T, Wood S, Chua R, Walmsley S. Evaluation of the Digene Hybrid Capture System for detection and quantitation of human cytomegalovirus viremia in human immunodeficiency virus-infected patients. J Clin Microbiol 1996; 12: 2959.
12. Veal N, Payan C, Fray D, Sarol L, et al. Novel DNA assay for cytomegalovirus detection: comparison with conventional culture and pp65 antigenemia assay. J Clin Microbiol 1996; 12: 3097.
13. Rasmussen L, Morris S, Zipeto D, et al. Quantitation of human cytomegalovirus DNA from peripheral blood cells of immunodeficiency virus-infected patients could predict cytomegalovirus retinitis. J Infect Dis 1995; 171: 177.
14. Rawal BK, Booth JC, Fernando S, Butcher PD, Powles RL. Quantification of cytomegalovirus DNA in blood specimens from bone marrow transplant recipients by the polymerase chain reaction. J Virol Methods 1994; 47: 189.
15. Imbert-Marcille BM, Poirier AS, Cantarovich D, et al. Cytomegalovirus leukocytic viral load determination using direct detection of antigenemia by flow cytometry and quantitative-competitive PCR [Abstract 178]. Presented at the Sixth International Cytomegalovirus Workshop, Orange Beach, AL, March 5-9, 1997.
16. Ho M. Cytomegalovirus: biology and infection, 2nd ed. New York: Plenum, 1991: 249.
17. Dunn DL, Mayoral JL, Gillingham KJ, et al. Treatment of invasive cytomegalovirus disease in solid organ transplant patients with ganciclovir. Transplantation 1991; 51: 98.
18. Pillay D, Ali AA, Liu SF, Kops E, Sweny P, Griffiths PD. The prognostic significance of positive CMV cultures during surveillance of renal transplant recipients. Transplantation 1993; 56: 103.
19. Pouteil-Noble C, Ecochard R, Landrivon G, et al. Cytomegalovirus infection: an etiological factor for rejection? Transplantation 1993; 55: 851.
20. Gerna G, Zipeto D, Parea M, et al. Monitoring of human cytomegalovirus infections and ganciclovir treatment in heart transplant recipients by determination of viremia, antigenemia, and DNAemia. J Infect Dis 1991; 164: 488.
21. Wolf DG, Spector SA. Early diagnosis of human cytomegalovirus disease in transplant recipients by DNA amplification in plasma. Transplantation 1993; 56: 330.
22. Einsele H, Ehninger G, Hebart H, et al. Polymerase chain reaction monitoring reduces the incidence of cytomegalovirus disease and the duration and side effects of antiviral therapy after bone marrow transplantation. Blood 1995; 86: 2815.
23. Blancho G, Josien R, Bignon JD, et al. The influence of HLA-A-B-DR matching on Cytomegalovirus disease after transplantation. Transplantation 1992; 54: 871.