The ability to cleave 28S ribosomal RNA during apoptosis is a cell-type dependent trait unrelated to DNA fragmentation

Cell Death and Differentiation

Volumn 4, Issue 4, 1997, Pages 289-293

  Samali, Afshin ^a   Gilje, Bjornar ^b   Døskeland, Stein O ^b   Cotter, Thomas G ^a   Houge, Gunnar ^b,c  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY OF BERGEN   (Norway)

^c Dept of Anatomy and Cell Biology ^*  (Norway)

Author keywords

Apoptosis; DNA fragmentation; p53; Ribosome; rRNA cleavage

Indexed keywords

DNA FRAGMENT; OKADAIC ACID; RIBOSOME DNA; RNA 28S;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL TYPE; CONTROLLED STUDY; DNA CLEAVAGE; ETIOLOGY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; RNA CLEAVAGE; TEMPERATURE SENSITIVE MUTANT;

EID: 0030921985     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400246     Document Type: Article

References (26)

1. Bøe R, Gjertsen BT, Vintermyr O, Houge G, Lanotte M and Døskeland SO (1991) The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells. Exp Cell Res. 195: 237 - 246
2. Chomczynsky P and Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156 - 159
3. Chow VT, Quek HH and Tock EP (1993) Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphobiastic leukemia cell line. Cancer Lett. 73: 141 - 148
4. Fontoura BMA, Sorokina EA, David E and Carroll RB (1992) p53 is Covalently Linked to 5.8S rRNA. Mol. Cell. Biol. 12: 5145 - 5151
5. Fraser MJ (1994) Endo-exonucleases: Enzymes involved in DNA repair and cell death? BioEssays 16: 761 - 766
6. Gjertsen BT and Døskeland SO (1995) Protein phosphorylation in apoptosis. Biochem Biophys. Acta 1269: 187 - 199
7. Han Z, Chatteriee D, Early J, Pantazis P, Hendrickson EA and Wyche JH (1996) Isolation and Characterization of an Apoptosis-resistant Vanant of Human Leukemia HL-60 Cells That has Switched Expression from Bcl-2 to Bcl-X(L). Cancer Res. 56: 1621 - 1628
8. Holmberg L, MelanderY and Nygård O (1994) Probing the structure of mouse Ehrlich ascites cell 5 8S, 18S and 28S ribosomal RNA in situ. Nucleic Acids Res. 22: 1374 - 1382
9. Houge G and Døskeland SO (1996) Divergence towards a dead end? Cleavage of the divergent domains of ribosomal RNA in apoptosis. Expenentia 52: 963 - 967
10. Houge G, Døskeland SO, Bøe R and Lanotte M (1993) Selective cleavage of 28S rRNA variable regions V3 and V13 in myeloid leukemia cell apoptosis. FEBS Lett. 315: 16 - 20
11. Houge G, Robaye B, Eikhom TS, Golstein J, Mellgren G, Gjertsen BT, Lanotte M and Døskeland SO (1995) Fine Mapping of 28S rRNA Sites Specifically Cleaved in Cells Undergoing Apoptosis. Mol. Cell. Biol. 15: 2051 - 2062
12. Houge G, Vintermyr OK and Døskeland SO (1990) The Expression of cAMP-Dependent protein Kinase in Primary Rat Hepatocyte Cultures. Cyclic AMP Down-Regulates Its Own Effector Systemby Decreasing the Amount of Catalytic Subunit and Increasing the mRNAs for the Inhibitory (R) subunits of cAMP-Dependent Protein Kinase. Mol. Endocrin. 4: 481 - 488
13. Jarvis WD, Foman FA, Traylor RS, Martin HA, Kramer LB, Erukulla RK, Bittman R and Grant S (1996) Induction of apoptosis and potenfiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. J Biol. Chem. 271 8275 - 8284
14. Lee JM and Bernstein A (1996) Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev. 14: 149 - 161
15. Leffers H and Andersen AH (1993) The sequence of 28S ribosomal RNA varies within and between human cell lines Nucl Acids Res. 21: 1449 - 1455
16. Michot B and Bachellene JP (1987) Comparisons of large subunit rRNAs reveal some eukaryote-specific elements of secondary structure Biochimie 69: 11 - 23
17. Raué HA, Klootwijk J and Musters W (1988) Evolutionary conservation of structure and function of high molecular weight ribosmal RNA Prog. Biophys. molec. Biol. 51. 77 - 129
18. Samad A and Carroll RB (1991) The tumor suppressor p53 is bound to RNA by a stable covalent linkage. Mol. Cell. Biol. 11: 1598 - 1606
19. Samali A and Cotter TG (1996) Heat shock proteins increase resistance to apoptosis. Exp Cell Res. 223: 163 - 170
20. Sambrook J, Fritsch EF and Maniatis T (1989). Molecular Cloning, a laboratory manual (New York. Cold Spring Harbor Laboratory Press)
21. Shiohara M, Akashi M, Gombart AF, Yang R and Koeffler HP (1996) Tumor necrosis factor alpha: posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemia cells. J. Cell. Physiol. 166: 568 - 576
22. Suarez P, Diaz-Guerra M, Pneto C, Esteban M, Castro JM, Nieto A, Ortin J (1996) Open Reading Frame 5 of Porcine Reproductive and Respiratory Syndrome Virus as a Cause of Virus-Induced Apoptosis. J. Virol. 70: 2876 - 2882
23. Sucai B, Hughes T, Bungey J, Chase A, di Fabritiis P and Goldman JM (1992) p53 in chronic myeloid leukemia cell lines. Leukemia 6. 839 - 842
24. Soddu S, Blandino G, Scardigli R, Coen S, Marchetti A, Rizzo MG, Bossi G, Cimino L, Crescenzi M and Sacci A (1996) Interference with p53 protein inhibits hematopoietic and muscle differentiation J. Cell Biol. 134: 193 - 204
25. Sugimoto K, Toyoshima H, Sakai R, Miyagawa K, Hagiwara K, Ishikawa F, Yakaku F, Yazaki Y and Hirai H (1992) Frequent mutations in the p53 gene in human myeloid leukemia cell lines Blood 79: 2378 - 2383
26. Yonish-Rouach E, Grunwald D, Wilder S, Kimchi A, May E, Lawrence JJ, May P and Oren M (1993) p53-Mediated Cell Death - Relationship to Cell Cycle Control. Mol Cell. Biol. 13: 1415 - 1423