Mechanism of nitric oxide-dependent killing of Mycobacterium bovis BCG in human alveolar macrophages

Infection and Immunity

Volumn 65, Issue 9, 1997, Pages 3644-3647

  Nozaki, Yasuhiro ^a   Hasegawa, Yoshinori ^a   Ichiyama, Satoshi ^b   Nakashima, Izumi ^a   Shimokata, Kaoru ^b  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; N(G) METHYLARGININE; NITRIC OXIDE;

ARTICLE; BACTERIAL GROWTH; CELL KILLING; COLONY FORMATION; DRUG MECHANISM; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; LUNG ALVEOLUS MACROPHAGE; MYCOBACTERIUM BOVIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030921890     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.9.3644-3647.1997     Document Type: Article

References (30)

1. Bermudez, L. E. 1993. Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide. Clin. Exp. Immunol. 91:277-281.
2. Bloom, B. R., and C. J. Murray. 1992. Tuberculosis: commentary on a reemergent killer. Science 257:1055-1064.
3. Cameron, M. L., D. L. Granger, J. B. Weinberg, W. J. Kozumbo, and H. S. Koren. 1990. Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. Am. Rev. Respir. Dis. 142:1313-1319.
4. Chan, J., Y. Xing, R. S. Magliozzo, and B. R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111-1122.
5. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
6. Denis, M. 1994. Human monocytes/macrophages: NO or no NO? J. Leukocyte Biol. 55:682-684.
7. Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407-2412.
8. Drapier, J. C., J. Wietzerbin, and J. J. Hibbs. 1988. Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18:1587-1592.
9. Edwards, D., and C. H. Kirkpatrick. 1986. The immunology of mycobacterial diseases. Am. Rev. Respir. Dis. 134:1062-1071.
10. Elliott, A. M., N. Luo, G. Tembo, B. Halwiindi, G. Steenbergen, L. Machiels, J. Pobee, P. Nunn, R. J. Hayes, and K. P. McAdam. 1990. Impact of HIV on tuberculosis in Zambia: a cross sectional study. Br. Med. J. 301:412-415.
11. Flesch, I. E., and S. H. Kaufmann. 1990. Activation of tuberculostatic macrophage functions by gamma interferon, interleukin-4, and tumor necrosis factor. Infect. Immun. 58:2675-2677.
12. Flesch, I. E., and S. H. Kaufmann. 1991. Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates. Infect. Immun. 59:3213-3218.
13. 15N-nitrate in biological fluids. Anal. Biochem. 126:131-138.
14. Helfgott, D. C., S. B. Tatter, U. Santhanam, R. H. Clarick, N. Bhardwaj, L. T. May, and P. B. Sehgal. 1989. Multiple forms of IFN-beta 2/IL-6 in serum and body fluids during acute bacterial infection. J. Immunol. 142:948-953.
15. Holt, P. G. 1978. Inhibitory activity of unstimulated alveolar macrophages on T-lymphocyte blastogenic response. Am. Rev. Respir. Dis. 118:791-793.
16. Isobe, K., and I. Nakashima. 1993. Abundant production of nitric oxide from murine macrophages by direct stimulation of tumor cells. Biochem. Biophys. Res. Commun. 192:499-504.
17. Jackett, P. S., P. W. Andrew, V. R. Aber, and D. B. Lowrie. 1983. Guinea pig alveolar macrophages probably kill M. tuberculosis H37Rv and H37Ra in vivo by producing hydrogen peroxide. Adv. Exp. Med. Biol. 162:99-104.
18. Kawatsu, H., Y. Hasegawa, E. Takagi, and K. Shimokata. 1991. Human alveolar macrophages of anergic patients with lung cancer lack the responsiveness to recombinant interferon gamma. Chest 100:1277-1280.
19. Nibbering, P. H., S. I. Yoshida, M. T. van den Barselaar, and R. van Furth. 1994. Bacteriostatic activity of BCG/PPD-activated macrophages against Mycobacterium fortuitum does not involve reactive nitrogen or oxygen intermediates. Scand. J. Immunol. 40:187-194.
20. Nozaki, Y., K. Isobe, I. Nakashima, and K. Shimokata. 1993. Tumor cytotoxicity of nitric oxide produced from alveolar macrophages directly stimulated with tumor cells. Int. J. Oncol. 2:1053-1057.
21. Oswald, I. P., R. T. Gazzinelli, A. Sher, and S. L. James. 1992. IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity. J. Immunol. 148:3578-3582.
22. Rees, D. D., R. M. Palmer, R. Schulz, H. F. Hodson, and S. Moncada. 1990. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101:746-752.
23. Roach, T. I., D. Chatterjee, and J. M. Blackwell. 1994. Induction of early-response genes KC and JE by mycobacterial lipoarabinomannans: regulation of KC expression in murine macrophages by Lsh/Ity/Bcg (candidate Nramp). Infect. Immun. 62:1176-1184.
24. Schneemann, M., G. Schoedon, S. Hofer, N. Blau, L. Guerrero, and A. Schaffner. 1993. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J. Infect. Dis. 167:1358-1363.
25. Schoedon, G., J. Troppmair, A. Fontana, C. Huber, H. C. Curtius, and A. Niederwieser. 1987. Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse. Eur. J. Biochem. 166:303-310.
26. Stamler, J. S., D. J. Singel, and J. Loscalzo. 1992. Biochemistry of nitric oxide and its redox-activated forms. Science 258:1898-1902.
27. van der Vliet, A., J. P. Eiserich, C. A. O'Neill, B. Halliwell, and C. E. Cross. 1995. Tyrosine modification by reactive nitrogen species: a closer look. Arch. Biochem. Biophys. 319:341-349.
28. Walker, C., W. Bauer, R. K. Braun, G. Menz, P. Braun, F. Schwarz, T. T. Hansel, and B. Villiger. 1994. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia. Am. J. Respir. Crit. Care Med. 150:1038-1048.
29. Werner, E. R., F. G. Werner, D. Fuchs, A. Hausen, G. Reibnegger, and H. Wachter. 1989. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma. Biochem. J. 262:861-866.
30. Zhu, L., C. Gunn, and J. S. Beckman. 1992. Bactericidal activity of peroxynitrite. Arch. Biochem. Biophys. 298:452-457.