The sheep kidney contains a novel unidirectional, high affinity NADP+- dependent 11β-hydroxysteroid dehydrogenase (11β-HSD-3)

Steroids

Volumn 62, Issue 5, 1997, Pages 444-450

  Gomez Sanchez, Elise P ^a,b,c   Ganjam, Venkataseshu ^b   Chen, Yuan Jian ^b   Diana L, Cox ^b   Zhou, Ming Yi ^b   Thanigaraj, Srihari ^b   Gomez Sanchez, Celso E ^b  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

11 Hydroxysteroid dehydrogenase; Cortisol; Cortisone; Kidney; Mineralocorticoid receptor

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; KIDNEY ENZYME; LIVER ENZYME; MINERALOCORTICOID RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; NONHUMAN; RECEPTOR BINDING; SHEEP;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CORTICOSTERONE; GLYCYRRHETINIC ACID; HYDROXYSTEROID DEHYDROGENASES; KIDNEY; NAD; NADP; SHEEP;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; OVIS ARIES; PYRONIA TITHONUS;

EID: 0030921425     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(97)00011-1     Document Type: Article

References (35)

1. Arriza JL, Simerly RB, Swanson LW, Evans RM (1988). The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1:887-900.
2. Wrange O, Yu Z-Y (1983). Mineralocorticoid receptor in rat kidney and hippocampus: Characterization and quantitation by isoelectric focusing. Endocrinology 113:243-250.
3. Krozowski ZS, Funder JW (1983). Renal mineralocorticoid receptors and hippocampal corticosterone binding species have identical intrinsic steroid specificity. Proc Natl Acad Sci USA 80:6056-6060.
4. Beaumont K, Fanestil DD (1983). Characterization of rat brain aldosterone receptors reveals high affinity for corticosterone. Endocrinology 113:2043-2051.
5. Funder JW, Pearce PT, Smith R, Smith AI (1988). Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585.
6. Edwards CRW, Burt D, McIntyre MA, De Kloet ER, Stewart PM, Brett L, Sutanto WS, Monder C (1988). Localization of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet ii:986-989.
7. Teelucksingh S, Mackie ADR, Burt D, McIntyre MA, Brett L, Edwards CRW (1990). Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Lancet 1:1060-1063.
8. Seckl JR, Dow RC, Low SC, Edwards CRW, Fink G (1993). The 11β-hydroxysteroid dehydrogenase inhibitor glycyrrhetinic acid affects corticosteroid feedback regulation of hypothalamic corticotrophin-releasing petides in rats. J Endocrinol 136:471-477.
9. Seckl JR, Brown RW, Rajan V, Low SC, Edwards CRW (1993). 11β-Hydroxysteroid dehydrogenase and corticosteroid actions in the brain. J Endocrinol 137:S9.
10. Edwards CRW, Benediktsson R, Lindsay RS, Seckl JR (1993). Dysfunction of placental glucocorticoid barrier: Link between fetal environment and adult hypertension. Lancet 341:355-357.
11. Agarwal AK, Monder C, Eckstein B, White PC (1989). Cloning and expression of rat cDNA encoding corticosteroid 11 beta-dehydrogenase, J Biol Chem 264:18,939-18,943.
12. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS (1994). Cloning and tissue distribution of the human 11b-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocr 105:R11-R17.
13. +-dependent isoform of 11β-hydroxysteroid dehydrogenase. J Biol Chem 269:25,959-25,962.
14. Seckl JR (1993). 11β-hydroxysteroid dehydrogenase isoforms and their implications for blood pressure regulation. Euro J Clin Invest 23:589-601.
15. Rundle SE, Funder JW, Lakshmi V, Monder C (1989). The intrarenal localization of mineralocorticoid receptors and 11β-dehydrogenase: Immunocytochemical studies. Endocrinology 125:1700-1704.
16. Krozowski Z, Maguire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK (1995). Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol Metab 80:2203-2209.
17. Naray-Fejes-Toth A, Fejes-Toth G (1995). Expression cloning of the aldosterone target cell-specific 11b-hydroxysteroid dehydrogenase from rabbit collecting duct cells. Endocrinology 136:2579-2586.
18. +-dependent 11b-hydroxysteroid dehydrogenase. Endocrinology 136:3729-3734.
19. Yang K, Yu M (1994). Evidence for distinct isoforms of 11β-hydroxysteroid dehydrogenase in the ovine liver and kidney. J Steroid Biochem Mol Biol 49:245-250.
20. Steward PM, Murry BA, Mason JI (1994). Human kidney 11β-hydroxysteroid dehydrogenase is a high-affinity nicotinamide adenine dinucleotide dependent enzyme and differs from the cloned type I isoform. J Clin Endocrinol Metab 79:480-484.
21. Brown RW, Chapman KE, Edwards CRW, Seckl JR (1993). Human placental 11b-hydroxysteroid dehydrogenase: Evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology 132:2614-2621.
22. Yang K, Smith CL, Dales D, Hammond GL, Challis JR (1994). Cloning of an ovine 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: Tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development. Endocrinology 131:2120-2126.
23. Heffernan M, Dennis JW (1991). Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in chinese hamster ovary cells. Nucleic Acids Res 19:85-92.
24. Low SC, Assaad SN, Rajan V, Chapman KE, Edwards CRW, Seckl JR (1993). Regulation of 11β-hydroxysteroid dehydrogenase by sex steroids in vivo: Further evidence for the existence of a second dehydrogenase in rat kidney. J Endocrinol 139:27-35.
25. Ulick S, Ramirez LC, New MI (1977). An abnormality in steroid reductive metabolism in a hypertensive syndrome. J Clin Endocrinol Metab 44:799-802.
26. Ulick S, Levine LS, Gunczler P (1979). A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab 49:757-764.
27. Stewart PM, Corrie JET, Shackleton CHL, Edwards CRW (1988). Syndrome of apparent mineralocorticoid excess: A defect in the cortisol-cortisone shuttle. J Clin Invest 82:340-349.
28. Wilson RC, Krozowski ZS, Li K, Obeyesekere VR, Razzaghy-Azar M, Harbison MD, Wei JQ, Shackleton CHL, Funder JW, New MI (1995). A mutation in the HSD11β2 gene in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab 80:2263-2266.
29. Mune T, Rogerson FM, Nikkilä H, Agarwal AK, White PC (1995). Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase, Nature Genetics 10:394-399.
30. Kornel L, Starnes WR, Hill SR Jr, Hill A (1969). Studies on steroids conjugates: VI. Quantitative paper chromatography of urinary corticosteroids in essential hypertension. J Clin Endocrinol Metab 29:1608-1617.
31. Kornel L, Margolis E (1992). Evidence for overall deficiency of cortisol 11β-hydroxydehydrogenase in patients with essential hypertension. Proceedings of the 9th International Congress of Endocrinology abst 142.
32. Walker BR, Stewart PM, Shackleton CH, Padfield PL, Edwards CRW (1993). Deficient inactivation of cortisol by 11β-hydroxysteroid dehydrogenase in essential hypertension. Clin Endocrinol 39:221-227.
33. Gomez-Sanchez EP (1995). Mineralocorticoid modulation of central control of blood pressure. Steroids 60:69-72.
34. Gomez-Sanchez EP, Gomez-Sanchez CE (1992). Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone. Am J Physiol 263:E1125-E1130.
35. Gomez-Sanchez CE, Gomez-Sanchez EP, Yamakita N (1995). Endocrine causes of hypertension. Sem Nephr 15:106-115.