Blushing and social phobia: A neuroethological speculation

Medical Hypotheses

Volumn 49, Issue 1, 1997, Pages 101-108

  Stein, D J ^a   Bouwer, C ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE; CHLORPROPAMIDE; DISULFIRAM; NICOTINIC ACID; SEROTONIN; VASODILATOR AGENT;

ALCOHOL CONSUMPTION; HUMAN; NEUROBIOLOGY; NONVERBAL COMMUNICATION; PRIORITY JOURNAL; PSYCHOBIOLOGY; PSYCHODYNAMICS; REVIEW; SEIZURE; SEROTONIN SYNDROME; SOCIAL PHOBIA; VASODILATATION;

EID: 0030920467     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(97)90260-7     Document Type: Article

References (81)

1. Darwin C. The Expression of the Emotions in Man and Animals. Chicago: Chicago University Press, 1872/1965.
2. Twain M. Following the Equator, Vol. I. New York: Harper and Brothers, 1897.
3. Amies P L, Gelder M G, Shaw P M. Social phobia: A comparative clinical study. Br J Psychiatry 1983; 142: 174-179.
4. Davidson J R T, Hughes D C, George L K et al. The boundary of social phobia: Exploring the threshold. Arch Gen Psychiatry 1994; 51: 975-983.
5. Schneier F R, Heckelman L R, Garfinkel R et al. Functional impairment in social phobia. J Clin Psychiatry 1994; 55: 322-331.
6. Burgess T. The Physiology or Mechanism of Blushing. London: Churchill, 1839.
7. Leary M R, Cutlip W D II, Brit T W, Templeton J L. Social blushing. Psychological Bull 1992; 3: 446-460.
8. Ray D, Williams G. Pathophysiological causes and clinical significance of flushing. Br J Hosp Med 1993; 50: 594-598.
9. Edelmann R J. The Psychology of Embarrassment. New York: Wiley, 1987.
10. Leary M R, Meadows S. Predictors, elicitors, and concomitants of social blushing. J Pers Soc Psychol 1991; 60: 254-262.
11. Edelmann R J, Iwawaki S. Self-reported expression and consequences of embarrassment in the United States and Japan. Psychologica: An International Journal of Psychology in the Orient 1987; 30: 205-211.
12. Edelmann R K, Asendorpf J, Contarello A et al. Self-reported expression of embarrassment in five European cultures. J Cross-Cultural Psychol 1989; 20: 357-371.
13. Buss A H, Iscoe I, Buss E H. The development of embarrassment. J Psychology 1979; 103: 227-230.
14. Asendorpf J. The expression of shyness and embarrassment. In: Crozier W R, ed. Shyness and Embarrassment: Perspectives from Social Psychology. Cambridge: Cambridge University Press, 1990.
15. Baldwin J M. Social and Ethical Interpretations in Mental Development. London: Macmillan, 1906.
16. Van der Meer C. Pharmacotherapy of idiopathic excessive blushing and hyperhidrosis. Acta Neurochirurgica 1985; 74: 151-152.
17. Buck R W, Parke R D. Behavioral and physiological response to the presence of a friendly or neutral person in two types of stressful situations. J Person Soc Psychol 1972; 24: 143-153.
18. Mellander S, Andersson P, Afzelius L et al. Neural beta-adrenergic dilatation of the facial vein in man: Possible mechanism in emotional blushing. Acta Physiol Scand 1982; 114: 393-399.
19. Mulley G P. Flushing. J Roy Coll Physicians 1978; 12: 359-364.
20. Wilkin J K. Why is flushing limited to a mostly facial cutaneous distribution? J Am Acad Dermatol 1988; 19: 309-313.
21. Waldenstrom J G. From maiden blush to matron's flush. Acta Med Scand 1977; 201: 1-2.
22. Campbell H. Flushing and Morbid Blushing. London: H K Lewis, 1980.
23. Aldrich L B, Moattaci A R, Vinik A I. Distinguishing features of idiopathic flushing and carcinoid syndrome. Arch Intern Med 1988; 148: 2614-2618.
24. Friedman B S, Germano P, Miletti J, Metcalfe D D. A clinico-pathologic study of ten patients with recurrent unexplained flushing. J Allergy Clin Immunol 1994; 93: 53-60.
25. Thorson A, Biorck G, Bjorkman G et al. Malignant carcinoid of the small intestine with metastases to the liver, valvular disease of the right side of the heart (pulmonary stenosis and tricuspid regurgitation without septal defects), peripheral vasomotor symptoms, bronchoconstriction, and an unusual type of cyanosis. Am Heart J 1954; 47: 795-817.
26. Bider D, Mashiach S, Serr D M et al. Endocrinological basis of hot flushes. Obstet Gynecol Surv 1989; 44: 495-499.
27. Travis W D, Chin-Yang L, Bergstrath E J. Systemic mast cell disease: analysis of 58 cases and review of the literature. Medicine 1988; 67: 345-367.
28. Drummond P D, Gonski A, Lance J W. Facial flushing after thermocoagulation of the Gasserian ganglion. J Neurol Neurosurg Psychiatry 1983; 46: 611-618.
29. Saito H. Congenital Horner's syndrome with unilateral facial flushing. J Neurol Neurosurg Psychiatry 1990; 53: 85-86.
30. Devinsky O, Hafler D A, Victor J. Embarrassment as the aura of a complex partial seizure. Neurology 1982; 32: 1284-1285.
31. Lembeck F. 5-hydroxytryptamine in a carcinoid tumour. Nature 1953; 172: 910-911.
32. Wilkin J K, Feldman J M. Facial flushing is not blushing. N Engl J Med 1976; 294: 116-117.
33. Robertson J I S, Pearl W S, Andrews T M. The mechanism of facial flush in the carcinoid syndrome. Q J Med 1962; 31: 103-122.
34. Oates J A, Melmon K, Sjoerdsma A et al. Release of a kinin peptide in the carcinoid syndrome. Lancet 1964; 1: 514-517.
35. Mason D T, Melmon K L. New understanding of the mechanism of carcinoid flush. Ann Intern Med 1966; 65: 1334-1339.
36. Sandler M, Karim S, Williams E. Prostaglandins in amine-peptide-secreting tumors. Lancet 1968; 2: 1053-1055.
37. Gustafsen J, Boesby S, Nielsen et al. Bradykinin in carcinoid syndrome. Gut 1987; 28: 1417-1419.
38. Grahame-Smith D G. What is the cause of the carcinoid flush? Gut 1987; 28: 1413-1416.
39. Frolich et al. 1978.
40. Ginsberg J, Hardiman P, O'Reilly B. Peripheral blood flow in menopausal women who have hot flushes and in those who do not. Br Med J 1989; 298: 1488-1490.
41. Ginsberg J, O'Reilly B, Swinhoe J. Effect of oral clonidine on human vascular responsiveness: a possible explanation of the therapeutic action of the drug in menopausal flushing and migraine. Br J Obstet Gynaecol 1985; 92: 1169-1175.
42. Roberts L J, Sweetman B J, Lewis R A et al. Increased production of prostaglandin D2 in patients with systemic mastocytosis. Nature 1980; 303: 1400-1404.
43. Wilkin J K, Wilkin O, Kapp R et al. Aspirin blocks nicotinic acid-induced flushing. Clin Pharmacol Ther 1982; 31: 478-482.
44. Wilkin J K, Fortner G, Reinhardt L A et al. Prostaglandins and nicotinate-provoked increase in cutaneous blood flow. Clin Pharmacol Ther 1985; 38: 273-277.
45. Morrow J D, Parsons W G III, Roberts L J II. Release of markedly increased quantities of prostaglandin D2 in vivo in humans following administration of nicotinic acid. Prostaglandins 1989; 38: 263-274.
46. Hatake K, Taniguchi T, Ouchi H et al. Possible involvement of kinins in cardiovascular changes after alcohol intake. Pharmacol Biochem Behav 1990; 35: 437-442.
47. Sternbach H. The serotonin syndrome. Am J Psychiatry 1991; 148: 705-713.
48. Karch F E. Blushing. Psychoanalytic Review 1971; 58: 37-50.
49. Alexander F. The Psychoanalysis of the Total Personality. New York: Nervous and Mental Disease Publishing, 1930.
50. Schnenk J M. Blushing and unconscious hostility. Dis Nerv System 1967; 28: 679.
51. Nathanson D L, ed. The Many Faces of Shame. New York: Guilford, 1987.
52. Skinner B J. Science and Human Behavior. New York: Macmillan, 1953.
53. Sattler J M. Embarrassment and blushing: A theoretical review. J Soc Psychol 1966; 69: 117-133.
54. Gibbs D N. Reciprocal inhibition therapy of a case of symptomatic erythema. Behav Res Ther 1965; 2: 261-266.
55. Boeringa J A. Blushing: A modified behavioral intervention using paradoxical intention. Psychotherapy 1983; 20: 441-444.
56. Lamontagne Y. Treatment of erythrophobia by paradoxical intention. J Nerv Ment Dis 1978; 1656: 304-306.
57. Scholing A, Emmelkamp P M. Cognitive and behavioural treatments of fear of blushing, sweating or trembling. Behav Res Ther 1993; 31: 155-170.
58. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington: American Psychiatric Press, 1994.
59. Marshall R D, Schneier F R, Fallon B A et al. Medication therapy for social phobia. J Clin Psychiatry 1994; 55S: 33-37.
60. Tancer M E. Neurobiology of social phobia. J Clin Psychiatry 1993; 54S: 26-30.
61. MacCurdy J. The biological significance of blushing and shame. Br J Psychol 1930; 21: 174-182.
62. Lewis H B. Shame and the narcissistic personality. In: Nathanson D L, ed. The Many Faces of Shame. New York: Guilford, 1987.
63. Castelfranchi C, Poggi I. Blushing as a discourse: Was Darwin wrong? In: Crozier W R, ed. Shyness and Embarrassment: Perspectives from Social Psychology. Cambridge: Cambridge University Press, 1990.
64. Semin G R, Manstead A S R. The social implications of embarrassment displays and restitution behavior. Eur J Soc Psychol 1982; 12: 367-377.
65. Bolwig N. Communicative signals and social behavior of some African monkeys: A comparative study. Primates 1978; 19: 61-99.
66. Hinde R A. Expression and negotiation. In: Zivin G, ed. The Development of Expressive Behavior. San Diego: Academic Press, 1985.
67. Frijda N H. The Emotions. Cambridge: Cambridge University Press, 1986.
68. Plesch E. Rosacea and morbid reddening: some psychoanalytic aspects. Psychosomatic Med 1960; 22: 377-390.
69. Hutt C, Ounsted C. The biological significance of gaze aversion with specific reference to the syndrome of infantile autism. Behavioral Sci 1966; 11: 346-356.
70. Altmann S A. The structure of primate communication. In: Altmann S A, ed. Social Communication among Primates. Chicago: University of Chicago Press, 1967.
71. Van Hoof. A comparative approach to the phylogeny of laughter and smiling. In: Hinde R A, ed. Non-Verbal Communication. Cambridge: Cambridge University Press, 1972.
72. Goodall J. In the Shadow of Man. Boston: Houghton Mifflin, 1988.
73. Crozier W R, Russell D. Blushing, embarrassability and self-consciousness. Br J Soc Psychol 1992; 31: 343-349.
74. Edelmann R J. Chronic blushing, self-consciousness and social anxiety. J Psychopathol Behav Assess 1990; 12: 119-127.
75. Shearn D, Bergman E, Hill K et al. Blushing increases with audience size. Psychophysiology 1989; 26: S56.
76. Klein D F. False suffocation alarms, spontaneous panics, and related conditions: An integrative hypothesis. Arch Gen Psychiatry 1993; 50: 306-317.
77. Stein D J, Hollander E. Cognitive science and obsessive-compulsive disorder. In: Stein D J, Young J E, eds. Cognitive Science and Clinical Disorders. San Diego: Academic Press, 1992.
78. Fyer A J, Mannuzza S, Chapman T F et al. Specificity in familial aggregation of phobic disorders. Arch Gen Psychiatry 1995; 52: 564-573.
79. Raleigh M J, Brammer G L, McGuire M T. Male dominance, serotonergic systems, and the behavioral and physiological effects of drugs in vervet monkeys (Cercopithecus aethiops sabaeus). In: Miczek K A, ed. Ethopharmacology: Primate Models of Neuropsychiatric Disorders. New York: Alan RLiss, 1983.
80. Mehlman P T, Higley J D, Faucher I et al. Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates. Am J Psychiatry 1995; 152: 907-913.
81. Black B, Uhde T W, Tancer M W. Fluoxetine for the treatment of social phobia. J Clin Psychopharmacol 1992; 12: 293-295.