Identification of an oligodeoxynucleotide sequence motif that specifically inhibits phosphorylation by protein tyrosine kinases

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 2, 1997, Pages 115-123

  Krieg, Arthur M ^a,b   Matson, Sara ^a   Cheng, Kunrong ^a   Fisher, Eric ^c   Koretzky, Gary A ^a   Koland, John G ^a  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; OLIGODEOXYNUCLEOTIDE; PHOSPHOROTHIOIC ACID; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RECOMBINANT ENZYME;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0030919682     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.115     Document Type: Article

References (8)

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2. BERGAN, R.C., KYLE, E., CONNELL, Y., and NECKERS, L. (1995). Inhibition of protein tyrosine kinase activity in intact cells by the aptameric action of oligodeoxynucleotides. Antisense Res. Dev. 5, 33-38.
3. BOCK, L.C., GRIFFIN, L.C., LATHAM, J.A., VERMAAS, E.H., and TOOLE, J.J. (1992). Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 355, 564-566.
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7. KOLAND, J.G., and CERIONE, R.A. (1988). Growth factor control of epidermal growth factor receptor kinase activity via an intramolecular mechanism. J. Biol. Chem. 263, 2230-2237.
8. ZHAO, Q., MATSON, S., HERRARA, C.J., FISHER, E., YU, H., WAGGONER, A., and KRIEG, A.M. (1993). Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides. Antisense Res. Dev. 3, 53-66.