L-aspartate but not the D form is secreted through microvesicle-mediated exocytosis and is sequestered through Na+-dependent transporter in rat pinealocytes

Journal of Neurochemistry

Volumn 69, Issue 1, 1997, Pages 340-347

  Yatsushiro, Shouki ^a   Yamada, Hiroshi ^a,e   Kozaki, Shunji ^b   Kumon, Hiromi ^d   Michibata, Hitoshi ^a   Yamamoto, Akitsugu ^c   Moriyama, Yoshinori ^a,e  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

^d OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Aspartate transporter; D Aspartate; Exocytosis; Glutamate transporter; L Aspartate; Microvesicles (synaptic like microvesicles); Pineal gland

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; SODIUM ION; SYNAPTOPHYSIN;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CELLULAR DISTRIBUTION; ENANTIOMER; EXOCYTOSIS; NEWBORN; NONHUMAN; PINEALOCYTE; PRIORITY JOURNAL; RAT; SYNAPSE VESICLE;

ANIMALIA; BOVINAE;

EID: 0030919370     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69010340.x     Document Type: Article

References (42)

1. Ahnert-Hilger G. and Weidenmann B. (1992) The amphicrine pancreatic cell line, AR42J, secretes GABA and amylase by separate regulated pathways. FEBS Lett. 314, 41-44.
2. Annaert W. G., Llona I., Backer A. C., Jacob W. A., and De Potter W. P. (1993) Catecholamines are present in a synaptic-like microvesicle-enriched fraction from bovine adrenal medulla. J. Neurochem. 60, 1746-1754.
3. Araki M. (1992) Cellular mechanism for norepinephrine suppression of pineal photoreceptor-like cell differentiation in rat pineal cultures. Dev. Biol. 149, 440-447.
4. Arriza J. L., Fairman W. A., Jwadiche I. G., Murdoch H., Kavanaugh M. P., and Amara S. G. (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J. Neurosci. 14, 5559-5569.
5. Axelrod J. (1974) The pineal gland: a neurochemical transducer. Science 184, 1341-1348.
6. Bauerfeind R., Regnier-Vigouroux A., Flatmark T., and Huttner W. B. (1993) Selective storage of acetylcholine, but not catecholamines, in neuroendocrine synaptic-like microvesicles of early endosomal origin. Neuron 11, 105-121.
7. Bellemann P. and Frankowiak G. (1985) Different receptor affinities of the enantiomers of Bay K 8644, a dihydropyridine calcium channel activator. Eur. J. Pharmacol. 118, 187-194.
8. Binz T., Blasi J., Yamasaki S., Baumeister A., Link E., Südhof T. C., Jahn R., and Niemann H. (1994) Proteolysis of SNAP-25 by type E and A botulinum neurotoxins. J. Biol. Chem. 269, 1617-1620.
9. Dijk S. N., Francis P. T., Stratmann G. C., and Bowen D. M. (1995) NMDA-induced glutamate and aspartate release from rat cortical pyramidal neurons: evidence for modulation by a 5-HT1A antagonist. Br. J. Pharmacol. 115, 1169-1174.
10. Foran P., Lawrence G., and Dolly J. O. (1995) Blockade by botulinum neurotoxin B of catecholamine release from adrenochromaffin cells correlates with its cleavage of synaptobrevin and a homologue present on the granules. Biochemistry 34, 5495-5503.
11. Godel H., Graser T., Foeldi P., and Fuerst P. (1984) Measurements of free amino acids in human biological fluids by high-performance liquid chromatography. J. Chromatogr. 297, 49-61.
12. Govitrapong P. and Ebadi M. (1988) The inhibition of pineal aryl-alkylamine N-acetyltransferase by glutamic acid and its analogues. Neurochem. Int. 13, 223-230.
13. 2+ channels. Neuron 9, 69-77.
14. Imai K., Fukushima T., Hagiwara K., and Senta T. (1995) Occurrence of D-aspartic acid in rat brain pineal gland. Biomed. Chromatogr. 9, 106-109.
15. Jeftinija S. D., Jeftinija K. V., Stefanovic G., and Liu F. (1996) Neuroligand-evoked calcium-dependent release of excitatory amino acids from cultured astrocytes. J. Neurochem. 66, 676-684.
16. Kamata Y., Kimura Y., Hiroi T., Sakaguti G., and Kozaki S. (1993) Purification and characterization of the ganglioside-binding fragment of Clostridium botulinum type E neurotoxin. Biochim. Biophys. Acta 1156, 213-218.
17. Kanner B. and Schuldiner S. (1987) Mechanism of transport and storage of neurotransmitters. CRC Crit. Rev. Biochem. 22, 1-38.
18. Kato K., Fukushima T., Santa T., Homma H., and Imai K. (1995) Determination of D-amino acids, derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F), in wine samples by high performance liquid chromatography. Biomed. Chromatogr. 9, 193-194.
19. Klein D. C. (1985) Photoneural regulation of the mammalian pineal gland, in Ciba Foundation Symposium 117: Photoperiodism, Melatonin, and the Pineal Gland (Evered D. and Clark S., eds), pp. 38-56. Pitman, London.
20. Kus L., Handa R. J., and McNulty J. A. (1994) Glutamate inhibition of the adrenergic-stimulated production of melatonin in rat pineal gland in vitro. J. Neurochem. 62, 2241-2245.
21. Mintz I. M., Venema V. J., Swiderek K. M., Lee T. D., Bean B. P., and Adams M. E. (1992) P-type calcium channels blocked by the spider toxin ω-Aga-IVA. Nature 355, 827-829.
22. Moriyama Y. and Yamamoto A. (1995a) Microvesicles isolated from bovine pineal gland specifically accumulate L-glutamate. FEBS Lett. 367, 233-236.
23. Moriyama Y. and Yamamoto A. (1995b) Vesicular L-glutamate transporter in microvesicles from bovine pineal glands: driving force, mechanism of chloride anion-activation, and substrate specificity. J. Biol. Chem. 270, 22314-22320.
24. Moriyama Y., Yamamoto A., Yamada H., Tashiro Y., Takahashi M., Tomochika K., Maeda M., and Futai M. (1995) Microvesicles isolated from bovine posterior pituitary accumulate noradrenaline. J. Biol. Chem. 270, 11424-11429.
25. Moriyama Y., Yamamoto A., Yamada H., Tashiro Y., and Futai M. (1996) Role of endocrine cell microvesicles in intercellular chemical transduction. Biol. Chem. Hoppe Seyler 377, 155-165.
26. Naito S. and Ueda T. (1985) Characterization of glutamate uptake into synaptic vesicles. J. Neurochem. 44, 99-109.
27. Nowycky M. C., Fox A. P., and Tsien R. W. (1985) Three types of neuronal calcium channel with different calcium agonist sensitivity. Nature 316, 440-449.
28. Obata K., Nishiya H., Fujita S. C., Shirao T., Inoue H., and Uchizono K. (1986) Identification of a synaptic vesicle-specific 38,000-dalton protein by monoclonal antibodies. Brain Res. 375, 37-48.
29. Ogata T., Nakamura Y., Shibata T., and Kataoka K. (1992) Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation. J. Neurochem. 58, 1957-1959.
30. Olivera B. M., McIntosh J. M., Cruz L. J., Luque F. A., and Gray W. R. (1984) Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23, 5087-5090.
31. Redecker P. and Bargsten G. (1993) Synaptophysin - a common constituent of presumptive secretory microvesicles in the mammalian pinealocyte: a study of rat and gerbil pineal glands. J. Neurosci. Res. 34, 79-96.
32. Reiter R. J. (1981) The mammalian pineal gland: structure and function. Am. J. Anat. 162, 287-313.
33. Reiter R. J. (1991) Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr. Rev. 12, 151-180.
34. A-receptor chloride channels. Nature 341, 233-236.
35. Sadoul K., Lang J., Montecucco C., Weller U., Regazzi R., Catsicas S., Wollheim C. B., and Halban P. A. (1995) SNAP-25 is expressed in islets of Langerhans and is involved in insulin release. J. Cell Biol. 128, 1019-1028.
36. Schiavo G., Santucci A., DasGupta B. R., Mehta P. P., Jontes J., Benfenati F., Wilson M. C., and Montecucco C. (1993) Botulinum neurotoxin serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds. FEBS Lett. 335, 99-103.
37. Thomas-Reetz A. and De Camilli P. (1994) A role for synaptic vesicles in non-neuronal cells: clues from pancreatic β cells and from chromaffin cells. FASEB. J. 8, 209-216.
38. Tsien R. W., Lipscombe D., Madison D. V., Bley K. R., and Fox A. P. (1988) Multiple types of neuronal calcium channels and their selective modulation. Trends Neurosci. 11, 431-438.
39. van Wyk E. and Daya S. (1994) Glutamate inhibits the isoprenaline-induced raise in melatonin synthesis by organ cultures of rat pineal glands. Med. Sci. Res. 22, 635-636.
40. Xu C. J., Klunk W. E., Kanfer J. N., Xiong Q., Miller G., and Pettegrew J. W. (1996) Phosphocreatine-dependent glutamate uptake by synaptic vesicles: a comparison with ATP-dependent glutamate uptake. J. Biol. Chem. 271, 13435-13440.
41. Yamada H., Yamamoto A., Yodozawa S., Kozaki S., Takahashi M., Morita M., Furuichi T., Mikoshiba K., and Moriyama Y. (1996a) Microvesicle-mediated exocytosis of glutamate is a novel paracrine-like signal transducing mechanism, and inhibits melatonin secretion in rat pinealocytes. J. Pineal Res. 21, 175-191.
42. 2+ channel is involved in microvesicle-mediated glutamate exocytosis from rat pinealocytes. J. Pineal Res. 21, 165-174.