Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis

Archives of Physical Medicine and Rehabilitation

Volumn 78, Issue 5, 1997, Pages 521-524

  Mueller, Marguerite E ^a   Gruenthal, Michael ^a   Olson, Walter L ^a   Olson, William H ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GABAPENTIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; MUSCLE SPASM; ORAL DRUG ADMINISTRATION; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SPASTICITY; SYMPTOMATOLOGY; TREATMENT OUTCOME;

EID: 0030919233     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9993(97)90168-4     Document Type: Article

References (24)

1. Maynard FM, Karunas RS, Waring WP. Epidemiology of spasticity following traumatic spinal cord injury. Arch Phys Med Rehabil 1990;71:566-9.
2. Levine IM, Jossmann PB, DeAngelis V. Lioresal, a new muscle relaxant in the treatment of spasticity - a double-blind quantitative evaluation. Dis Nerv System 1977;38:1011-5.
3. Chyatte SB, Basmajian JV. Dantrolene sodium: long-term effects in severe spasticity. Arch Phys Med Rehabil 1973;54:311-5.
4. Nance PW, Shears AH, Nance DM. Reflex changes induced by clonidine in spinal cord injured patients. Paraplegia 1989;27:296-301.
5. Hattab JR. Review of European clinical trials with baclofen. In: Feldman RG, Young RR, Koella WP, editors. Spasticity: disorders motor control. Chicago: Year Book Medical Publishers, 1979:71-85.
6. Joynt RL. Dantrolene sodium: long-term effects in patients with muscle spasticity. Arch Phys Med Rehabil 1976;57:212-7.
7. Corston RN, Johnson F, Godwin-Austen RB. The assessment of drug treatment of spastic gait. J Neurol Neurosurg Psychiatry 1981; 44:1035-9.
8. Smith CS, Birnbaum G, Carter JL, Greenstein J. Tizanidine treatment of spasticity caused by multiple sclerosis: results of a double-blind, placebo-controlled trial. Neurology 1994;44 Suppl:S34-43.
9. Konstanzer A, Ceballos-Baumann AO, Dressnandt J, Conrad B. Local injection treatment with botulinum toxin A in severe arm and leg spasticity. Nervenarzt 1993;64:517-23.
10. Penn RD, Savoy SM, Corcos D, Latash M, Gottlieb G, Parke B, et al. Intrathecal baclofen for severe spinal spasticity. N Engl J Med 1989;320:1517-21.
11. Coffey RJ, Cahill D, Steers W, Park TS, Ordia J, Meythaler J, et al. Intrathecal baclofen for intractable spasticity of spinal origin: results of a long-term multicenter study. J Neurosurg 1993;78:226-32.
12. Loubser PG, Narayan RK, Sandin KJ, Donovan WH, Russell KD. Continuous infusion of intrathecal baclofen: long-term effects on spasticity in spinal cord injury. Paraplegia 1991;29:48-64.
13. Price DD, McGrath PA, Rafii A, Buckingham B. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain 1983;17:45-56.
14. Ashworth B. Preliminary trial of carisoprodol in multiple sclerosis. Practitioner 1964;192:540-2.
15. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52.
16. McLean MJ. Clinical pharmacokinetics of gabapentin. Neurology 1994;44 Suppl:S17-22.
17. McLean MJ. Gabapentin. Epilepsia 1995;36 Suppl:S73-86.
18. Handforth A, Treiman DM. Efficacy and tolerance of long-term, high-dose gabapentin: additional observations. Epilepsia 1994;35: 1032-7.
19. Hill DR, Suman-Chauhan N, Woodruff GW. Localization of [3H]-gabapentin to a novel site in rat brain: autoradiographic studies. Eur J Pharmacol 1993;244:303-9.
20. Suman-Chauhan N, Webdale L, Hill DR, Woodruff GN. Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies. Eur J Pharmacol - Mol Pharmacol Section 1993;224:293-301.
21. Loscher W, Honack D, Taylor CP. Gabapentin increases aminooxy-acetic acid-induced GABA accumulation in several regions of rat brain. Neurosci Lett 1991;128:150-4.
22. Petroff OAC, Rothman DL, Behor KL, Lamoureaux D, Mattson RH. Gabapentin increases brain gama-aminobutyric levels in patients with epilepsy [abstract]. Ann Neurol 1995;38:295.
23. Priebe MM, Sherwood AM. A quantitative study of the effects of gabapentin on spasticity [abstract]. J Spinal Cord Med 1996;19: 289.
24. Priebe MM, Sherwood AM, Graves D, Mueller M, Olson WH. Effectiveness of gabapentin in controlling spasticity: a quantitative study. Spinal Cord. Forthcoming.