Association between serum levels of total IgA and IgA class endomysial and antigliadin antibodies: Implications for coeliac disease screening

European Journal of Gastroenterology and Hepatology

Volumn 9, Issue 6, 1997, Pages 559-562

  Dickey, William ^a   McMillan, Stanley A ^b   McCrum, Evelyn E ^c   Evans, Alun E ^c  

^a ALTNAGELVIN HOSPITAL   (United Kingdom)

^b ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Antigliadin antibody; Coeliac disease; Diagnosis; Endomysial antibody; Immunoglobulin A deficiency

Indexed keywords

ENDOMYSIUM ANTIBODY; GLIADIN ANTIBODY; IMMUNOGLOBULIN A;

ADOLESCENT; ADULT; AGED; ANTIBODY BLOOD LEVEL; ARTICLE; CELIAC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEFICIENCY; INTESTINE BIOPSY; INTESTINE VILLUS ATROPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHOOL CHILD;

EID: 0030919166     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199706000-00002     Document Type: Article

References (17)

1. Ferreira M, Lloyd Davies S, Butler M, et al.: Endomysial antibody: is it the best screening test for coeliac disease? Gut 1992, 33:1633-1637.
2. Grodzinsky E, Hed J, Skogh T: IgA endomysium antibodies have a high positive predictive value for celiac disease in asymptomatic patients. Allergy 1994, 49:593-597.
3. Collin P, Maki M: Associated disorders in coeliac disease: clinical aspects. Scand J Gastroenterol 1994, 29:769-775.
4. McMillan SA, Haughton DJ, Biggart JD, et al.: Predictive value for coeliac disease of antibodies to gliadin, endomysium, and jejunum in patients attending for jejunal biopsy. BMJ 1991, 303:1163-1165.
5. McMillan SA, Watson RCP, McCrum EE, et al.: Factors associated with serum antibodies to reticulin, endomysium and gliadin in an adult population. Gut 1996, 39:43-47.
6. Liblau RS, Bach JF: Selective IgA deficiency and autoimmunity. Int Arch Allergy Immunol 1992, 99:16-27.
7. Crabbe PA, Heremans JF: Selective IgA deficiency with steatorrhea. Am J Med 1967, 42:319-326.
8. Collin P, Maki M, Keyrilainen O, et al.: Selective IgA deficiency and coeliac disease. Scand J Gastroenterol 1992, 27:367-371.
9. Asquith P, Thompson RA, Cooke WT: Serum immunoglobulins in adult coeliac disease. Lancet 1969, ii:129-131.
10. Klemola T, Savilahti E, Arato A, et al.: Immunohistochemical findings in jejunal specimens from patients with IgA deficiency. Gut 1995, 37:519-523.
11. Savilahti E, Pelkonen P, Verkasalo M, et al.: Selective deficiency of immunoglobulin A. Klin Padiatr 1985, 197:336-340.
12. Uibo O, Uibo B, Kleimola V, et al.: Serum IgA anti-gliadin antibodies in an adult population sample. High prevalence without celiac disease. Dig Dis Sci 1993, 38:2034-2037.
13. Fox U, Lucani C: Disorders of the intestinal mesenteric lymphatic system. Lymphology 1993, 26:61-63.
14. Zinneman HH, Kaplan AP: The association of giardiasis with reduced intestinal secretory immunoglobulins. Am J Dig Dis 1972, 17:793-797.
15. Klemola T: Immunohistochemical findings in the jejunum of IgA-deficient persons: number of intraepithelial T lymphocytes is increased. J Pediatr Gastroenterol Nutr 1988, 7:537-543.
16. Buckely RH, Dees SC: Correlation of milk precipitins with IgA deficiency. N Engl J Med 1969, 281:465-469.
17. Cunningham-Rundles C, Brandeis WE, Day NB: Bovine antigens and the formation of circulating immune complexes in selective immunoglobulin A deficiency. J Clin Invest 1979, 64:272-279.