A ras homologue of Neurospora crassa regulates morphology

Molecular and General Genetics

Volumn 254, Issue 4, 1997, Pages 427-432

  Kana uchi, A ^a   Yamashiro, C T ^b,e   Tanabe, S ^c   Murayama, T ^d  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY   (United States)

^c TOHOKU UNIVERSITY   (Japan)

^d KANTO GAKUIN UNIVERSITY   (Japan)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Apical growth; Morphology; Neurospora; ras Homologue; smco7

Indexed keywords

RAS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL WALL; CONSENSUS SEQUENCE; DELETION MUTANT; FUNGUS HYPHAE; GENETIC LINKAGE; MOLECULAR CLONING; MORPHOLOGY; NEUROSPORA CRASSA; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CELL DIFFERENTIATION; CELL DIVISION; CLONING, MOLECULAR; FUNGAL PROTEINS; GENES, FUNGAL; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; NEUROSPORA CRASSA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RAS PROTEINS; RESTRICTION MAPPING; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSFORMATION, GENETIC;

FUNGI; NEUROSPORA; NEUROSPORA CRASSA;

EID: 0030918507     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050435     Document Type: Article

References (38)

1. Altschuler DL, Muro A, Schijman A, Almonacid FB, Torres HN (1990) Neurospora crassa cDNA clones coding for a new member of the ras protein family. FEBS Lett 273:103-106
2. Barbacid M (1987) ras genes. Annu Rev Biochem 56:779-827
3. Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349:117-127
4. Collinge AJ, Trinci APJ (1974) Hyphal tips of the wild type and spreading colonial mutants of Neurospora crassa. Arch Microbiol 99:353-368
5. Corrochano LM, Lauter FR, Ebbole DJ, Yanofsky C (1995) Light and developmental regulation of the gene can-10 of Neurospora crassa. Dev Biol 167:190-200
6. 32P-based hybridizations. Anal Biochem 210:235-244
7. Garnjobst L, Tatum EL (1967) A survey of new morphological mutants in Neurospora crassa. Genetics 57:579-604
8. Geever RF, Case ME, Tyler BM, Buxton F, Giles NH (1983) Point mutations and DNA rearrangements 5′ to the inducible qa-2 gene of Neurospora allow activator protein-independent transcription. Proc Natl Acad Sci USA 80:7298-7302
9. Geever RF, Murayama T, Case ME, Giles NH (1986) Rearrangement mutations on the 5′ side of the qa-2 gene of Neurospora implicate two regions of qa-1F activator-protein interaction. Proc Natl Acad Sci USA 83:3944-3948
10. Gooday GW (1971) An autoradiographic study of hyphal growth of some fungi. J General Microbiol 34:491-496.
11. Han M, Sternberg PW (1990) let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell 63:921-931.
12. Heintz K, Palme K, Diefenthal T, Russo VE (1992) The Ncyptl gene from Neurospora crassa is located on chromosome 2. Mol Gen Genet 235:413-421
13. Howard RJ (1981) Ultrastructural analysis of hyphal tip cell growth in fungi:Spitzenkörper, cytoskeleton and endomembranes after freeze-substitution. J Cell Sci 48:89-103
14. Huiet L, Case ME (1985) Molecular biology of the qa gene cluster of Neurospora. In: Bennett JW, Lasure LL (eds) Gene manipulations in fungi. Academic Press, London, pp 229-244
15. Kana-uchi A, Murayama T (1996) Formation of a large number of conidia. Fungal Genet Newslett 43:27
16. Kataoka T, Powers S, McGill G, Fasano O, Strathern J, Broach J, Wigler M (1984) Genetic analysis of yeast RAS1 and RAS2 genes. Cell 37:437-445
17. Kore-eda S, Murayama T, Uno I (1991) Isolation and characterization of the adenylate cyclase structural gene of Neurospora crassa. Jpn J Genet 66:317-334
18. Kozak M(1986) Point mutational define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292
19. Madi L, Ebbole DJ, White BT, Yanofsky C (1994) Mutants of Neurospora crassa that alter gene expression and conidia development. Proc Natl Acad Sci USA 91:6226-30
20. Matsuyama SS, Nelson RE, Siegel RW (1974) Mutations specifically blocking differentiation of macroconidia in Neurospora crassa. Dev Biol 41:278-287
21. Metzenberg RL, Grotelueschen J (1992) Restriction polymorphism maps of Neurospora crassa. Fungal Genet Newslett 40:130-138
22. Metzenberg RL, Stevens JN, Selker EU, Morzycka-Wroblewsku E (1985) Identification and chromosomal distribution of 5S rRNA gene in Neurospora crassa. Proc Natl Acad Sci USA 82:2067-2071
23. Morgan MP, Garnjobst L, Tatum EL (1967) Linkage relations of new morphological mutants in linkage group V of Neurospora crassa. Genetics 57:605-612
24. Nelson RE, Selitrennikoff CP, Siegel RW (1975) Cell change in Neurospora. In: Reinert J, Holzer H (eds) Results and problems in cell differentiation. Springer-Verlag, Berlin, pp 291-310
25. Orbach M, Sachs M (1991) The Orbach/Sachs cosmid library of N.crassa DNA sequences (pMOcosX). Fungal Genet Newslett 38:97
26. Perkins DD (1992) Neurospora crassa genetic maps, June 1992. Fungal Genet Newslelt 39:61-70
27. Sachs M (1991) cDNA libraries constructed by Matthew Sachs. Fungal Genet. Newslett 38:97
28. Segev N, Mulholland J, Botstein D (1988) the yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery. Cell 52:915-924
29. Singer MJ, Marcotte BA, Selker EU (1995) DNA methylation associated with Repeat-Induced Point mutation in Neurospora crassa. Mol Cell Biol 15:5586-5597
30. Som T, Kolaparthi VSR (1994) Developmental decisions in Aspergillus nidulans are modulated by Ras activity. Mol Cell Biol 14:5333-5348
31. Südhof TC (1995) The synuptic vesicle cycle: a cascade of protein-protein interactions. Nature 375:645-653
32. Tamanoi F, Hsueh EC, Goodman LE, Cobitz AR, Detrick RJ, Brown WR, Fujiyama A (1988) Posttranslational modification of RAS proteins: detection of a modification prior to fatty acid acylation and cloning of a gene responsible for the modification. J Cell Bioehem 36:261-274
33. Toda T, Uno I, Ishikawa T, Powers S, Kataoka T, Broek D, Cameron S, Broach J, Matsumoto K, Wigler M (1985) In yeast, RAS proteins are controlling elements of adenylyl cyclase. Cell 40:27-36
34. Turian G, Bianchi DE (1972) Conidiation in Neurospora. Bot Rev 38:119-154
35. Westergaard M, Mitchell HK (1947) Neurospora V. A synthetic medium favoring sexual reproduction. Amer J Bot 34:573-577
36. White BT, Yanofsky C (1993) Structural characterization and expression analysis of the Neurospora conidiation gene con-6. Dev Biol 160:254-64
37. Yarden O, Plamann M, Ebbole DJ, Yanofsky C (1992) cot-1, a gene required for hyphal elongation in Neurospora crassa, encodes a protein kinase. EMBO J 11:2159-2166
38. Zalokar M (1959) Growth and differentiation of Neurospora hyphae. Am J Bot 46:602-612