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Volumn 40, Issue 3, 1997, Pages 259-265

Disposition of irinotecan and SN-38 following oral and intravenous irinotecan dosing in mice

Author keywords

Irinotecan; Pharmacokinetics; SN 38

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; DRUG METABOLITE; IRINOTECAN;

EID: 0030917983     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050656     Document Type: Article
Times cited : (54)

References (31)
  • 1
    • 0028854897 scopus 로고
    • Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every three weeks in cancer patients
    • Abigerges D, Chabot GG, Armand J, Herait P, Gouyette A, Gandia D (1995) Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every three weeks in cancer patients. J Clin Oncol 13: 210
    • (1995) J Clin Oncol , vol.13 , pp. 210
    • Abigerges, D.1    Chabot, G.G.2    Armand, J.3    Herait, P.4    Gouyette, A.5    Gandia, D.6
  • 2
    • 0028029604 scopus 로고
    • Kinetic studies of the hydrolysis and lactonization of camptothecin and its derivatives, CPT-11 and SN-38, in aqueous solution
    • Akimoto K, Kawai A, Ohya K (1994) Kinetic studies of the hydrolysis and lactonization of camptothecin and its derivatives, CPT-11 and SN-38, in aqueous solution. Chem Pharm Bull 42: 2135
    • (1994) Chem Pharm Bull , vol.42 , pp. 2135
    • Akimoto, K.1    Kawai, A.2    Ohya, K.3
  • 3
    • 0025858296 scopus 로고
    • Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion
    • Atsumi R, Suzuki W, Hakusui H (1991) Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion. Xenobiotica 21: 1159
    • (1991) Xenobiotica , vol.21 , pp. 1159
    • Atsumi, R.1    Suzuki, W.2    Hakusui, H.3
  • 4
    • 0028937909 scopus 로고
    • The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs
    • Burke TG, Munshi CB, Mi Z, Jiang Y (1995) The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs. J Pharm Sci 84: 518
    • (1995) J Pharm Sci , vol.84 , pp. 518
    • Burke, T.G.1    Munshi, C.B.2    Mi, Z.3    Jiang, Y.4
  • 5
    • 1842393469 scopus 로고
    • Tumor influence on pharmacokinetics of the camptothecin analogue irinotecan (CPT-11) and active metabolite SN-38 in mice
    • Chabot GG, Gouyette A, Bissery MC (1994) Tumor influence on pharmacokinetics of the camptothecin analogue irinotecan (CPT-11) and active metabolite SN-38 in mice. Proc Am Assoc Cancer Res 35: 432
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 432
    • Chabot, G.G.1    Gouyette, A.2    Bissery, M.C.3
  • 6
    • 0027972726 scopus 로고
    • New drugs: Topoisomerase I inhibitors: Topotecan and ir[e]notecan
    • Creemers GJ, Lund B, Verweij J (1994) New drugs: topoisomerase I inhibitors: topotecan and ir[e]notecan. Cancer Treat Rev 20: 73
    • (1994) Cancer Treat Rev , vol.20 , pp. 73
    • Creemers, G.J.1    Lund, B.2    Verweij, J.3
  • 7
    • 84986505863 scopus 로고
    • The camptothecins: A reborn family of antitumor agents
    • Curran DP (1993) The camptothecins: a reborn family of antitumor agents. J Chinese Chem Soc 40: 1
    • (1993) J Chinese Chem Soc , vol.40 , pp. 1
    • Curran, D.P.1
  • 9
    • 0016052023 scopus 로고
    • Lethal activity of camptothecin sodium on human lymphoma cells
    • Drewinko B, Freireich EJ, Gottlieb JA (1974) Lethal activity of camptothecin sodium on human lymphoma cells. Cancer Res 34: 747
    • (1974) Cancer Res , vol.34 , pp. 747
    • Drewinko, B.1    Freireich, E.J.2    Gottlieb, J.A.3
  • 11
    • 0025912553 scopus 로고
    • Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin
    • Giovanella BC, Hinz HR, Kozielski AJ, Stehlin JS, Silber R, Potmesil M (1991) Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin. Cancer Res 51: 3052
    • (1991) Cancer Res , vol.51 , pp. 3052
    • Giovanella, B.C.1    Hinz, H.R.2    Kozielski, A.J.3    Stehlin, J.S.4    Silber, R.5    Potmesil, M.6
  • 12
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
    • Gupta E, Lestingi TM, Mick R, Ramirez J, Vokes EE, Ratain MJ (1994) Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res 54: 3723
    • (1994) Cancer Res , vol.54 , pp. 3723
    • Gupta, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Vokes, E.E.5    Ratain, M.J.6
  • 13
    • 0024537205 scopus 로고
    • Modification of the hydroxy lactone ring of camptothecin: Inhibition of mammalian topoisomerase I and biological activity
    • Hertzberg RP, Caranfa MJ, Holdern KG, Jakas DR, Gallagher G, Mattern MG (1989) Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity. J Med Chem 32: 715
    • (1989) J Med Chem , vol.32 , pp. 715
    • Hertzberg, R.P.1    Caranfa, M.J.2    Holdern, K.G.3    Jakas, D.R.4    Gallagher, G.5    Mattern, M.G.6
  • 15
  • 16
    • 0027324850 scopus 로고
    • Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: Lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl-10-hydroxycamptothecin
    • Houghton PJ, Cheshire PJ, Mallman JC, Bissery MC, Mathieu-Boue A, Houghton JA (1993) Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl-10-hydroxycamptothecin. Cancer Res 53: 2823
    • (1993) Cancer Res , vol.53 , pp. 2823
    • Houghton, P.J.1    Cheshire, P.J.2    Mallman, J.C.3    Bissery, M.C.4    Mathieu-Boue, A.5    Houghton, J.A.6
  • 17
    • 0024560495 scopus 로고
    • Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: Evidence for a specific receptor site and relations to antitumor activity
    • Jaxel C, Kohn KW, Wani MC, Wall ME, Pommier Y (1989) Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and relations to antitumor activity. Cancer Res 49: 1465
    • (1989) Cancer Res , vol.49 , pp. 1465
    • Jaxel, C.1    Kohn, K.W.2    Wani, M.C.3    Wall, M.E.4    Pommier, Y.5
  • 18
    • 0025342506 scopus 로고
    • Nonlinear pharmacokinetics of CPT-11 in rats
    • Kaneda N, Yokokura T (1990) Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res 50: 1721
    • (1990) Cancer Res , vol.50 , pp. 1721
    • Kaneda, N.1    Yokokura, T.2
  • 19
    • 0025272187 scopus 로고
    • Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
    • Kaneda N, Nagata H, Furuta T, Yokokura T (1990) Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res 50: 1715
    • (1990) Cancer Res , vol.50 , pp. 1715
    • Kaneda, N.1    Nagata, H.2    Furuta, T.3    Yokokura, T.4
  • 20
    • 0023552964 scopus 로고
    • Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
    • Kunimoto T, Nitta K, Tanka T, Uehara N, Baba H, Takeuchi M, Yokokura T, Sawada S, Miyasaka T, Mutai M (1987) Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res 47: 5944
    • (1987) Cancer Res , vol.47 , pp. 5944
    • Kunimoto, T.1    Nitta, K.2    Tanka, T.3    Uehara, N.4    Baba, H.5    Takeuchi, M.6    Yokokura, T.7    Sawada, S.8    Miyasaka, T.9    Mutai, M.10
  • 21
    • 0028225686 scopus 로고
    • Comparative activity of oral and parenteral topotecan in murine tumor models: Efficacy of oral topotecan
    • McCabe FL, Johnson RL (1994) Comparative activity of oral and parenteral topotecan in murine tumor models: efficacy of oral topotecan. Cancer Invest 12: 308
    • (1994) Cancer Invest , vol.12 , pp. 308
    • McCabe, F.L.1    Johnson, R.L.2
  • 22
    • 0027937924 scopus 로고
    • Reversed-phase high-performance liquid Chromatographic method for the simultaneous quantification of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma
    • Rivory LP, Robert J (1994) Reversed-phase high-performance liquid Chromatographic method for the simultaneous quantification of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma. J Chromatogr B Biomed Appl 661: 133
    • (1994) J Chromatogr B Biomed Appl , vol.661 , pp. 133
    • Rivory, L.P.1    Robert, J.2
  • 23
    • 0028670840 scopus 로고
    • Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients
    • Rivory LP, Chatelut E, Canal P, Mathieu-Boue A, Robert J (1994) Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients. Cancer Res 54: 6330
    • (1994) Cancer Res , vol.54 , pp. 6330
    • Rivory, L.P.1    Chatelut, E.2    Canal, P.3    Mathieu-Boue, A.4    Robert, J.5
  • 24
    • 0028158012 scopus 로고
    • Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-1-(1-piperidino)-1-piperdino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
    • Rowinsky EK, Grochow LB, Ettinger DS, Sartorius SE, Lubejko BG, Chen T (1994) Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-1-(1-piperidino)-1-piperdino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res 54: 427
    • (1994) Cancer Res , vol.54 , pp. 427
    • Rowinsky, E.K.1    Grochow, L.B.2    Ettinger, D.S.3    Sartorius, S.E.4    Lubejko, B.G.5    Chen, T.6
  • 25
    • 0028813952 scopus 로고
    • A pharmacokinetic and pharmacodynamic analysis of CPT-11 and its active metabolite, SN-38
    • Sasaki Y, Hakusui Y, Mizuno S, Morita M, Miya T, Eguchi K (1995) A pharmacokinetic and pharmacodynamic analysis of CPT-11 and its active metabolite, SN-38. Jpn J Cancer Res 86: 101
    • (1995) Jpn J Cancer Res , vol.86 , pp. 101
    • Sasaki, Y.1    Hakusui, Y.2    Mizuno, S.3    Morita, M.4    Miya, T.5    Eguchi, K.6
  • 26
    • 0028843263 scopus 로고
    • Pharmacological correlation between total drug concentration and lactones of CPT-11 and SN-38 in patients treated with CPT-11
    • Sasaki Y, Yoshida Y, Sudoh K, Hakusui H, Fuji H, Ohtsu T (1995) Pharmacological correlation between total drug concentration and lactones of CPT-11 and SN-38 in patients treated with CPT-11. Jpn J Cancer Res 86: 111
    • (1995) Jpn J Cancer Res , vol.86 , pp. 111
    • Sasaki, Y.1    Yoshida, Y.2    Sudoh, K.3    Hakusui, H.4    Fuji, H.5    Ohtsu, T.6
  • 28
    • 0028225471 scopus 로고
    • Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials
    • Tanizawa A, Fujimori A, Fujimori Y, Pommier Y (1994) Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. J Natl Cancer Inst 86: 836
    • (1994) J Natl Cancer Inst , vol.86 , pp. 836
    • Tanizawa, A.1    Fujimori, A.2    Fujimori, Y.3    Pommier, Y.4
  • 31
    • 0343029631 scopus 로고
    • Chemistry and antitumor activity of camptothecins
    • Potmesil M, Kohn KW (eds) Oxford University Press, New York
    • Wall ME, Wani MC (1991) Chemistry and antitumor activity of camptothecins. In: Potmesil M, Kohn KW (eds) DNA topoisomerases in cancer. Oxford University Press, New York, p 93
    • (1991) DNA Topoisomerases in Cancer , pp. 93
    • Wall, M.E.1    Wani, M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.