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Volumn 15, Issue 6-7, 1997, Pages 739-746

Oral delivery of purified lipoprotein OspA protects mice from systemic infection with Borrelia burgdorferi

Author keywords

Borrelia burgdorferi; oral vaccination; OspA

Indexed keywords

IMMUNOGLOBULIN A; LIPOPROTEIN; OUTER MEMBRANE PROTEIN; RECOMBINANT PROTEIN;

EID: 0030917704     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(97)00219-3     Document Type: Article
Times cited : (25)

References (47)
  • 1
    • 0020598076 scopus 로고
    • Lyme disease spirochetes and ixodid ticks share a common surface antigenic determinant defined by a monoclonal antibody
    • Barbour, A.G., Tessier, S.L. and Todd, W.J. Lyme disease spirochetes and ixodid ticks share a common surface antigenic determinant defined by a monoclonal antibody. Infect. Immun. 1983, 41, 795-804
    • (1983) Infect. Immun. , vol.41 , pp. 795-804
    • Barbour, A.G.1    Tessier, S.L.2    Todd, W.J.3
  • 2
    • 0024421344 scopus 로고
    • Molecular analysis of linear plasmid-encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi
    • Bergstrom, S., Bundoc, V.G. and Barbour, A.G. Molecular analysis of linear plasmid-encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi. Molec. Microbiol. 1989, 3, 479-486
    • (1989) Molec. Microbiol. , vol.3 , pp. 479-486
    • Bergstrom, S.1    Bundoc, V.G.2    Barbour, A.G.3
  • 3
    • 0025264283 scopus 로고
    • Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins
    • Brandt, M.E., Riley, B.S., Radolf, J.D. and Norgard, M.V. Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins. Infect. Immun. 1990, 58, 983-991
    • (1990) Infect. Immun. , vol.58 , pp. 983-991
    • Brandt, M.E.1    Riley, B.S.2    Radolf, J.D.3    Norgard, M.V.4
  • 4
    • 0028297815 scopus 로고
    • Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins
    • Belisle, J.T., Brandt, M.E., Radolf, J.D. and Norgard, M.V. Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins. Bacteriology 1994, 176, 2151-2157
    • (1994) Bacteriology , vol.176 , pp. 2151-2157
    • Belisle, J.T.1    Brandt, M.E.2    Radolf, J.D.3    Norgard, M.V.4
  • 5
    • 0027523763 scopus 로고
    • Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA
    • Erdile, L.F., Brandt, M., Warakomski, D.J. et al. Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA. Infect. Immun. 1993, 61, 81-90
    • (1993) Infect. Immun. , vol.61 , pp. 81-90
    • Erdile, L.F.1    Brandt, M.2    Warakomski, D.J.3
  • 6
    • 0025509132 scopus 로고
    • Outer surface protein A (OspA) from the Lyme disease spirochete, Borrelia burgdorferi. high level expression and purification of a soluble recombinant form of OspA
    • Dunn, J.J., Lade, B.N. and Barbour, A.G. Outer surface protein A (OspA) from the Lyme disease spirochete, Borrelia burgdorferi. high level expression and purification of a soluble recombinant form of OspA. Protein Expression Purif. 1990, 1, 159-168
    • (1990) Protein Expression Purif. , vol.1 , pp. 159-168
    • Dunn, J.J.1    Lade, B.N.2    Barbour, A.G.3
  • 7
    • 0029566940 scopus 로고
    • Crystallization and preliminary X-ray analysis of Borrelia burgdorferi outer surface protein A (OspA) complexed with a murine monoclonal antibody Fab fragment
    • Li, H. and Lawson, C.L. Crystallization and preliminary X-ray analysis of Borrelia burgdorferi outer surface protein A (OspA) complexed with a murine monoclonal antibody Fab fragment. J. Struct. Biol. 1995, 115, 335-337
    • (1995) J. Struct. Biol. , vol.115 , pp. 335-337
    • Li, H.1    Lawson, C.L.2
  • 8
    • 0027978073 scopus 로고
    • Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: Dependence on lipid modification
    • Weis, J.J., Ma, Y. and Erdile, L.F. Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modification. Infect. Immun. 1994, 62, 4632-4636
    • (1994) Infect. Immun. , vol.62 , pp. 4632-4636
    • Weis, J.J.1    Ma, Y.2    Erdile, L.F.3
  • 9
    • 0028940959 scopus 로고
    • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages
    • Radolf, J.D., Arndt, L.L., Akins, D.R. et al. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J. Immunol. 1995, 154, 2866-2877
    • (1995) J. Immunol. , vol.154 , pp. 2866-2877
    • Radolf, J.D.1    Arndt, L.L.2    Akins, D.R.3
  • 10
    • 0027327158 scopus 로고
    • Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties
    • Ma, Y. and Weis, J.J. Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties. Infect. Immun. 1993, 61, 3843-3853
    • (1993) Infect. Immun. , vol.61 , pp. 3843-3853
    • Ma, Y.1    Weis, J.J.2
  • 11
    • 0030025949 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine
    • de Silva, A.M., Telford III, S.R., Brunet, L.R., Barthold, S.W. and Fikrig, E. Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. Med. 1996, 183, 271-275
    • (1996) J. Exp. Med. , vol.183 , pp. 271-275
    • De Silva, A.M.1    Telford S.R. III2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 12
    • 0028200919 scopus 로고
    • Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A
    • Golde, W.T., Kappel, K.J., Dequesne, G. et al. Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A. Infect. Immun. 1994, 62, 2625-2627
    • (1994) Infect. Immun. , vol.62 , pp. 2625-2627
    • Golde, W.T.1    Kappel, K.J.2    Dequesne, G.3
  • 13
    • 0029024957 scopus 로고
    • Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme disease
    • Kalish, R.A., Leong, J.M. and Steere, A.C. Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme disease. Infect. Immun. 1995, 63, 2228-2235
    • (1995) Infect. Immun. , vol.63 , pp. 2228-2235
    • Kalish, R.A.1    Leong, J.M.2    Steere, A.C.3
  • 14
    • 0028926240 scopus 로고
    • Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
    • Schwan, T.G., Piesman, J., Golde, W.T., Dolan, M.C. and Rosa, P.A. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl Acad. Sci. USA 1995, 92, 2909-2913
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2909-2913
    • Schwan, T.G.1    Piesman, J.2    Golde, W.T.3    Dolan, M.C.4    Rosa, P.A.5
  • 16
    • 0025202254 scopus 로고
    • Protection of mice against the Lyme disease agent by immunizing with recombinant OspA
    • Fikrig, E., Barthold, S.W., Kantor, F.S. and Flavell, R.A. Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science 1990, 250, 553-556
    • (1990) Science , vol.250 , pp. 553-556
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 17
    • 0026507230 scopus 로고
    • Long-term protection of mice from Lyme disease by vaccination with OspA
    • Fikrig, E., Barthold, S.M., Kantor, F.S. and Flavell, R.A. Long-term protection of mice from Lyme disease by vaccination with OspA. Infect. Immun. 1992, 60, 773-777
    • (1992) Infect. Immun. , vol.60 , pp. 773-777
    • Fikrig, E.1    Barthold, S.M.2    Kantor, F.S.3    Flavell, R.A.4
  • 19
    • 0025723521 scopus 로고
    • Protection of mice from Lyme borreliosis by oral vaccination with Escherichia coli expressing OspA
    • Fikrig, E., Barthold, S.W., Kantor, F.S. and Flavell, R.A. Protection of mice from Lyme borreliosis by oral vaccination with Escherichia coli expressing OspA. J. Infect. Dis. 1991, 164, 1224-1227
    • (1991) J. Infect. Dis. , vol.164 , pp. 1224-1227
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 20
    • 0028904558 scopus 로고
    • Oral vaccination with an attenuated Salmonella typhimurium strain expressing Borrelia burgdorferi OspA prevents murine Lyme borreliosis
    • Dunne, M., Al-Ramadi, B.K., Barthold, S.W., Flavell, R.A. and Fikrig, E. Oral vaccination with an attenuated Salmonella typhimurium strain expressing Borrelia burgdorferi OspA prevents murine Lyme borreliosis. Infect. Immun. 1995, 63, 1611-1614
    • (1995) Infect. Immun. , vol.63 , pp. 1611-1614
    • Dunne, M.1    Al-Ramadi, B.K.2    Barthold, S.W.3    Flavell, R.A.4    Fikrig, E.5
  • 21
    • 0028079910 scopus 로고
    • Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borrelia burgdorferi
    • Langermann, S., Palaszynski, S., Sadziene, A., Stover, C.K. and Koenig, S. Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borrelia burgdorferi. Nature (London) 1994, 372, 552-555
    • (1994) Nature (London) , vol.372 , pp. 552-555
    • Langermann, S.1    Palaszynski, S.2    Sadziene, A.3    Stover, C.K.4    Koenig, S.5
  • 22
    • 0023146356 scopus 로고
    • The regulation of immune responses to dietary protein antigens
    • Mowat, A.M. The regulation of immune responses to dietary protein antigens. Immunol. Today 1988, 8, 93-98
    • (1988) Immunol. Today , vol.8 , pp. 93-98
    • Mowat, A.M.1
  • 23
    • 0020546234 scopus 로고
    • Local and systemic immune responses to intestinally presented antigen
    • Nicklin, S. and Miller, K. Local and systemic immune responses to intestinally presented antigen. Int. Archs Allergy appl. Immun. 1983, 72, 87-90
    • (1983) Int. Archs Allergy Appl. Immun. , vol.72 , pp. 87-90
    • Nicklin, S.1    Miller, K.2
  • 24
    • 0026488056 scopus 로고
    • Low-passage-associated proteins of Borrelia burgdorferi B31: Characterization and molecular cloning of OspD, a surface-exposed, plasmid-encoded lipoprotein
    • Norris, S.J., Carter, C.J., Howell, J.K. and Barbour, A.G. Low-passage-associated proteins of Borrelia burgdorferi B31: characterization and molecular cloning of OspD, a surface-exposed, plasmid-encoded lipoprotein. Infect. Immun. 1992, 60, 4662-4672
    • (1992) Infect. Immun. , vol.60 , pp. 4662-4672
    • Norris, S.J.1    Carter, C.J.2    Howell, J.K.3    Barbour, A.G.4
  • 25
    • 0028331281 scopus 로고
    • Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, OspC, but not with OspD or the 83-kilodalton antigen
    • Probert, W.S. and LeFebvre, R.B. Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, OspC, but not with OspD or the 83-kilodalton antigen. Infect. Immun. 1994, 62, 1920-1926
    • (1994) Infect. Immun. , vol.62 , pp. 1920-1926
    • Probert, W.S.1    LeFebvre, R.B.2
  • 27
    • 0023931860 scopus 로고
    • The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus)
    • Schwan, T.G., Burgdorfer, W., Schrumpf, M.E. and Karstens, R.H. The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus). Clin. Microbiol. 1988, 26, 893-895
    • (1988) Clin. Microbiol. , vol.26 , pp. 893-895
    • Schwan, T.G.1    Burgdorfer, W.2    Schrumpf, M.E.3    Karstens, R.H.4
  • 28
    • 0021671855 scopus 로고
    • Isolation and cultivation of Lyme disease spirochetes
    • Barbour, G. Isolation and cultivation of Lyme disease spirochetes. Yale J. Biol. Med. 1984, 57, 521-525
    • (1984) Yale J. Biol. Med. , vol.57 , pp. 521-525
    • Barbour, G.1
  • 29
    • 0028953918 scopus 로고
    • Borrelia burgdorferi mutant lacking Osp: Biological and immunological characterization
    • Sadziene, A., Thomas, D.D. and Barbour, A.C. Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization. Infect. Immun. 1995, 63, 1573-1580
    • (1995) Infect. Immun. , vol.63 , pp. 1573-1580
    • Sadziene, A.1    Thomas, D.D.2    Barbour, A.C.3
  • 30
    • 0026761405 scopus 로고
    • Antibody-resistant mutants of Borrelia burgdorferi: In vitro selection and characterization
    • Sadziene, A., Rosa, P.A., Thompson, P.A., Hogan, D.M. and Barbour, A.G. Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. J. Exp. Med. 1992, 176, 799-809
    • (1992) J. Exp. Med. , vol.176 , pp. 799-809
    • Sadziene, A.1    Rosa, P.A.2    Thompson, P.A.3    Hogan, D.M.4    Barbour, A.G.5
  • 31
    • 0021708880 scopus 로고
    • Immunochemical analysis of Lyme disease spirochaetes
    • Barbour, A.G. Immunochemical analysis of Lyme disease spirochaetes. Yale J. Biol. Med. 1984, 57, 581-586
    • (1984) Yale J. Biol. Med. , vol.57 , pp. 581-586
    • Barbour, A.G.1
  • 32
    • 0027509237 scopus 로고
    • In vitro inhibition of Borrelia burgdorferi growth by antibodies
    • Sadziene, A., Thompson, P.A. and Barbour, A.G. In vitro inhibition of Borrelia burgdorferi growth by antibodies. J. Infect. Dis. 1993, 167, 165172
    • (1993) J. Infect. Dis. , vol.167 , pp. 165172
    • Sadziene, A.1    Thompson, P.A.2    Barbour, A.G.3
  • 33
    • 0020383013 scopus 로고
    • Variable major proteins of Borrelia hermsii
    • Barbour, A.G., Tessier, S.L. and Stoenner, H. Variable major proteins of Borrelia hermsii. J. Exp. Med. 1982, 156, 1312-1324
    • (1982) J. Exp. Med. , vol.156 , pp. 1312-1324
    • Barbour, A.G.1    Tessier, S.L.2    Stoenner, H.3
  • 34
    • 0029898730 scopus 로고    scopus 로고
    • A flagella-less mutant of Borrelia burgdorferi as a live attenuated vaccine in the murine model of Lyme disease
    • Sadziene, A., Thompson, P.A. and Barbour, A.G. A flagella-less mutant of Borrelia burgdorferi as a live attenuated vaccine in the murine model of Lyme disease. J. Infect Dis. 1996, 173, 1184-1193
    • (1996) J. Infect Dis. , vol.173 , pp. 1184-1193
    • Sadziene, A.1    Thompson, P.A.2    Barbour, A.G.3
  • 35
    • 0026706705 scopus 로고
    • Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi
    • Rosa, P.A., Schwan, T. and Hogan, D. Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi. Molec. Microbiol. 1992, 6, 3031-3040
    • (1992) Molec. Microbiol. , vol.6 , pp. 3031-3040
    • Rosa, P.A.1    Schwan, T.2    Hogan, D.3
  • 36
    • 0029055060 scopus 로고
    • Oral immunization with a recombinant bacterial antigen produced in transgenic plants
    • Haq, T.A., Mason, H.S., Clements, J.D. and Arntzen, C.J. Oral immunization with a recombinant bacterial antigen produced in transgenic plants. Science 1995, 268, 714-716
    • (1995) Science , vol.268 , pp. 714-716
    • Haq, T.A.1    Mason, H.S.2    Clements, J.D.3    Arntzen, C.J.4
  • 37
    • 0027170656 scopus 로고
    • Oral vaccination of racoons (Procyon lotor) with baculovirus-expressed rabies virus glycoprotein
    • Fu, C.E., Rupprecht, C.E., Dietzschold, B. et al. Oral vaccination of racoons (Procyon lotor) with baculovirus-expressed rabies virus glycoprotein. Vaccine 1993, 11, 925-928
    • (1993) Vaccine , vol.11 , pp. 925-928
    • Fu, C.E.1    Rupprecht, C.E.2    Dietzschold, B.3
  • 38
    • 0029069313 scopus 로고
    • Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis
    • Lee, C.K., Weltzin, R. and Thomas, W.D. et al. Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis. J. Infect. Dis. 1995, 172, 161-172
    • (1995) J. Infect. Dis. , vol.172 , pp. 161-172
    • Lee, C.K.1    Weltzin, R.2    Thomas, W.D.3
  • 40
    • 0028798530 scopus 로고
    • Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells
    • Ermark, T.H., Dougherty, E.P., Bhagat, H.R., Kabok, Z. and Pappo, J. Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells. Cell Tissue Res. 1995, 279, 433-436
    • (1995) Cell Tissue Res. , vol.279 , pp. 433-436
    • Ermark, T.H.1    Dougherty, E.P.2    Bhagat, H.R.3    Kabok, Z.4    Pappo, J.5
  • 41
    • 0024461966 scopus 로고
    • Microparticles as potentially orally active immunological adjuvants
    • O'Hagan, D.T., Palin, K., Davis, S.S., Artursson, P. and Sjoholm, I. Microparticles as potentially orally active immunological adjuvants. Vaccine 1989, 7, 421-424
    • (1989) Vaccine , vol.7 , pp. 421-424
    • O'Hagan, D.T.1    Palin, K.2    Davis, S.S.3    Artursson, P.4    Sjoholm, I.5
  • 42
    • 0029417039 scopus 로고
    • Anti-γδ T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice
    • Mengel, J., Cardillo, F., Aroeira, L.S., Williams, O., Russo, M. and Vaz, N.M. Anti-γδ T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice. Immunol. Lett. 1995, 48, 97-102
    • (1995) Immunol. Lett. , vol.48 , pp. 97-102
    • Mengel, J.1    Cardillo, F.2    Aroeira, L.S.3    Williams, O.4    Russo, M.5    Vaz, N.M.6
  • 44
    • 0028139189 scopus 로고
    • Oral administration of an antigenic synthetic lipopeptide (MAP-P3C) evokes salivary anti-bodies and systemic humoral and cellular responses
    • Nardelli, B., Haser, P.B. and Tam, J.P. Oral administration of an antigenic synthetic lipopeptide (MAP-P3C) evokes salivary anti-bodies and systemic humoral and cellular responses. Vaccine 1994, 12, 1335-1339
    • (1994) Vaccine , vol.12 , pp. 1335-1339
    • Nardelli, B.1    Haser, P.B.2    Tam, J.P.3
  • 46
    • 0026471201 scopus 로고
    • Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant
    • Martinon, F., Gras-Masse, H., Boutillon, C. et al. Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. J. Immunol. 1992, 149, 3416-3422
    • (1992) J. Immunol. , vol.149 , pp. 3416-3422
    • Martinon, F.1    Gras-Masse, H.2    Boutillon, C.3
  • 47
    • 0027537675 scopus 로고
    • Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity
    • Akins, D.R., Purcell, B.K., Mitra, M.M., Norgard, M.V. and Radolf, J.D. Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity. Infect. Immun. 1993, 61, 1202-1210
    • (1993) Infect. Immun. , vol.61 , pp. 1202-1210
    • Akins, D.R.1    Purcell, B.K.2    Mitra, M.M.3    Norgard, M.V.4    Radolf, J.D.5


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