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Volumn 8, Issue 5, 1997, Pages 565-570

Phosphatidylinositol 3-kinase inhibitor Wortmannin blocks mitogenic activation of the transferrin receptor gene promoter in late G1

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; TRANSFERRIN RECEPTOR; WORTMANNIN;

EID: 0030917505     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (37)
  • 1
    • 0026563923 scopus 로고
    • Phosphatidylinositol 3-kinase: A key enzyme in diverse signalling processes
    • Panayotou, G., and Waterfield, M. D. Phosphatidylinositol 3-kinase: a key enzyme in diverse signalling processes. Trends Cell Biol., 2: 358-360, 1992.
    • (1992) Trends Cell Biol. , vol.2 , pp. 358-360
    • Panayotou, G.1    Waterfield, M.D.2
  • 2
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3-kinase
    • Kapeller, R., and Cantley, L. C. Phosphatidylinositol 3-kinase. Bioessays, 16: 565-576, 1994.
    • (1994) Bioessays , vol.16 , pp. 565-576
    • Kapeller, R.1    Cantley, L.C.2
  • 3
    • 0028095620 scopus 로고
    • Structure, regulation and function of phosphoinositide 3-kinases
    • Fry, M. J. Structure, regulation and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta, 1226: 237-268, 1994.
    • (1994) Biochim. Biophys. Acta , vol.1226 , pp. 237-268
    • Fry, M.J.1
  • 6
    • 0028018858 scopus 로고
    • The Phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin
    • Lam, K., Carpenter, C. L, Ruderman, N. B., Friel, J. C., and Kelly, K. L. The Phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin. J. Biol. Chem., 269: 20648-20652, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20648-20652
    • Lam, K.1    Carpenter, C.L.2    Ruderman, N.B.3    Friel, J.C.4    Kelly, K.L.5
  • 8
    • 0028239893 scopus 로고
    • RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
    • Sabatini, D. M., Erdjument-Bromage, H., Lui, M., Tempst, P., and Snyder, S. H. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell, 78: 35-43, 1994.
    • (1994) Cell , vol.78 , pp. 35-43
    • Sabatini, D.M.1    Erdjument-Bromage, H.2    Lui, M.3    Tempst, P.4    Snyder, S.H.5
  • 9
    • 0028022798 scopus 로고
    • Regulating S6 kinase
    • Downward, J. Regulating S6 kinase. Nature (Lond.), 377: 378-379, 1994.
    • (1994) Nature (Lond.) , vol.377 , pp. 378-379
    • Downward, J.1
  • 10
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B. M. T., and Coffer, P. J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature (Lond.), 376: 599-602, 1995.
    • (1995) Nature (Lond.) , vol.376 , pp. 599-602
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 11
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T. F., Yang, S-I., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R., and Tsichlis, P. N. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell, 87: 727-736, 1995.
    • (1995) Cell , vol.87 , pp. 727-736
    • Franke, T.F.1    Yang, S.-I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 12
    • 0027211693 scopus 로고
    • Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
    • Valius, M., and Kazlauskas, A. Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell, 73: 321-334, 1993.
    • (1993) Cell , vol.73 , pp. 321-334
    • Valius, M.1    Kazlauskas, A.2
  • 13
    • 0028584245 scopus 로고
    • The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors
    • Roche, S., Koegl, M., and Courtneidge, S. A. The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors. Proc. Natl. Acad. Sci. USA, 97: 9185-9189, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9185-9189
    • Roche, S.1    Koegl, M.2    Courtneidge, S.A.3
  • 14
    • 0020961467 scopus 로고
    • Transferrin receptor induction in mitogen-stimulated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin 2
    • Neckers, L. M., and Cossman, J. Transferrin receptor induction in mitogen-stimulated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin 2. Proc. Natl. Acad. Sci. USA, 80: 3494-3498, 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 3494-3498
    • Neckers, L.M.1    Cossman, J.2
  • 15
    • 0000302649 scopus 로고
    • Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro
    • Trowbridge, I. S., and Lopez, F. Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc. Natl. Acad. Sci. USA, 79: 1175-1179, 1982.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 1175-1179
    • Trowbridge, I.S.1    Lopez, F.2
  • 16
    • 0021795628 scopus 로고
    • Inhibition of cell growth by monoclonal anti-transferrin receptor antibodies
    • Lesley, J. F., and Schulte R. J. Inhibition of cell growth by monoclonal anti-transferrin receptor antibodies. Mol. Cell. Biol., 5: 1814-1821, 1985.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 1814-1821
    • Lesley, J.F.1    Schulte, R.J.2
  • 17
    • 0019951063 scopus 로고
    • Regulation of TR expression in concanavalin A stimulated and gross virus transformed rat lymphoblasts
    • Hamilton, T. A. Regulation of TR expression in concanavalin A stimulated and gross virus transformed rat lymphoblasts. J. Cell. Physiol., 113: 40-46, 1982.
    • (1982) J. Cell. Physiol. , vol.113 , pp. 40-46
    • Hamilton, T.A.1
  • 18
    • 0018603336 scopus 로고
    • Modulation of cell surface iron transferrin receptors by cellular density and state of activation
    • Larrick, J. W., and Cresswell, P. Modulation of cell surface iron transferrin receptors by cellular density and state of activation. J. Supramol. Struct., 11: 579-586, 1979.
    • (1979) J. Supramol. Struct. , vol.11 , pp. 579-586
    • Larrick, J.W.1    Cresswell, P.2
  • 19
    • 0019570604 scopus 로고
    • Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin
    • Trowbridge, I. S., and Omary, M. B. Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin. Proc. Natl. Acad. Sci. USA, 78: 3039-3043, 1981.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3039-3043
    • Trowbridge, I.S.1    Omary, M.B.2
  • 20
    • 0018850974 scopus 로고
    • Transferrin and transferrin receptors in carcinoma of the breast
    • Faulk, W. P., Hsi, B-L., and Stevens, P. J. Transferrin and transferrin receptors in carcinoma of the breast. Lancet, 2: 390-392, 1980.
    • (1980) Lancet , vol.2 , pp. 390-392
    • Faulk, W.P.1    Hsi, B.-L.2    Stevens, P.J.3
  • 21
    • 0022917310 scopus 로고
    • Transferrin receptor (TrfR) expression in breast carcinoma and its possible relationship to prognosis
    • Wrba, F., Ritzinger, E., Reiner, A., and Holzner, J. H. Transferrin receptor (TrfR) expression in breast carcinoma and its possible relationship to prognosis. Virchows Arch. A. Pathol. Anat., 410: 69-73, 1986.
    • (1986) Virchows Arch. A. Pathol. Anat. , vol.410 , pp. 69-73
    • Wrba, F.1    Ritzinger, E.2    Reiner, A.3    Holzner, J.H.4
  • 22
    • 0025332992 scopus 로고
    • Monoclonal antibody PAL-M1 recognizes the transferrin receptor and is a progression marker in melanocytic lesions
    • Van Muijen, G. N. P., Ruiter, D. J., Hoefakker, S., and Johnson, J. P. Monoclonal antibody PAL-M1 recognizes the transferrin receptor and is a progression marker in melanocytic lesions. J. Invest. Dermatol., 95: 65-69, 1990.
    • (1990) J. Invest. Dermatol. , vol.95 , pp. 65-69
    • Van Muijen, G.N.P.1    Ruiter, D.J.2    Hoefakker, S.3    Johnson, J.P.4
  • 23
    • 0027378151 scopus 로고
    • Proliferative activity of normal and neoplastic urothelium and its relation to epidermal growth factor and transferrin receptors
    • Limas, C., Bair, R., Bernhart, P., and Reddy, P. Proliferative activity of normal and neoplastic urothelium and its relation to epidermal growth factor and transferrin receptors. J. Clin. Pathol., 46: 810-816, 1993.
    • (1993) J. Clin. Pathol. , vol.46 , pp. 810-816
    • Limas, C.1    Bair, R.2    Bernhart, P.3    Reddy, P.4
  • 24
    • 0025275818 scopus 로고
    • Transferrin receptor expression in primary superficial human bladder tumours identifies patients who develop recurrences
    • Smith, N. W., Strutton, G. M., and Walsh, M. D. Transferrin receptor expression in primary superficial human bladder tumours identifies patients who develop recurrences. Br. J. Urol., 65: 339-344, 1990.
    • (1990) Br. J. Urol. , vol.65 , pp. 339-344
    • Smith, N.W.1    Strutton, G.M.2    Walsh, M.D.3
  • 26
    • 0021840709 scopus 로고
    • Sequential expression of genes involved in human T lymphocyte growth and differentiation
    • Kronke, M., Leonard, W. J., Depper, J. M., and Greene, W. C. Sequential expression of genes involved in human T lymphocyte growth and differentiation. J. Exp. Med., 161: 1593-1598, 1985.
    • (1985) J. Exp. Med. , vol.161 , pp. 1593-1598
    • Kronke, M.1    Leonard, W.J.2    Depper, J.M.3    Greene, W.C.4
  • 27
    • 0023543528 scopus 로고
    • Regulation of transferrin receptor expression in myeloid leukemia cells
    • Taetle, R., Ralph, S., Smedsrud, S., and Trowbridge, I. Regulation of transferrin receptor expression in myeloid leukemia cells. Blood, 70: 852-859, 1987.
    • (1987) Blood , vol.70 , pp. 852-859
    • Taetle, R.1    Ralph, S.2    Smedsrud, S.3    Trowbridge, I.4
  • 29
    • 0027502185 scopus 로고
    • Synergistic activation of a mitogen-responsive promoter region through multiple signalling pathways
    • Ouyang, Q., Bommakanti, M., and Miskimins, W. K. Synergistic activation of a mitogen-responsive promoter region through multiple signalling pathways. Mol. Cell. Biol., 13: 1796-1804, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1796-1804
    • Ouyang, Q.1    Bommakanti, M.2    Miskimins, W.K.3
  • 30
    • 0023037147 scopus 로고
    • Cell proliferation and expression of the transferrin receptor gene: Promoter sequence homologies and protein interactions
    • Miskimins, W. K., McClelland, A., Roberts, M. P., and Ruddle, F. H. Cell proliferation and expression of the transferrin receptor gene: promoter sequence homologies and protein interactions. J. Cell Biol., 103: 1781-1788, 1986.
    • (1986) J. Cell Biol. , vol.103 , pp. 1781-1788
    • Miskimins, W.K.1    McClelland, A.2    Roberts, M.P.3    Ruddle, F.H.4
  • 31
    • 0029005532 scopus 로고
    • Mitogen induction of nuclear factors that interact with a delayed responsive region of the transferrin receptor gene promoter
    • Hirsch, S., and Miskimins, W. K. Mitogen induction of nuclear factors that interact with a delayed responsive region of the transferrin receptor gene promoter. Cell Growth & Differ., 6: 719-726, 1995.
    • (1995) Cell Growth & Differ. , vol.6 , pp. 719-726
    • Hirsch, S.1    Miskimins, W.K.2
  • 32
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
    • Ui, M., Okada, T., Hazeki, K., and Hazeki, O. Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem. Sci., 20: 303-307, 1995.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 35
    • 0029127643 scopus 로고
    • ATM-related genes: What do they tell us about functions of the human gene?
    • Zakian, V. A. ATM-related genes: what do they tell us about functions of the human gene? Cell, 82: 685-687, 1995.
    • (1995) Cell , vol.82 , pp. 685-687
    • Zakian, V.A.1
  • 36
    • 0028856331 scopus 로고
    • When is a lipid kinase not a lipid kinase? When it is a protein kinase
    • Hunter, T. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell, 83: 1-4, 1995.
    • (1995) Cell , vol.83 , pp. 1-4
    • Hunter, T.1


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