Addition of C-nucleophiles to carbohydrate-derived 2,3-dihydro-4H-pyran-4-ones: A new entry to thriomboxane analogues

Tetrahedron

Volumn 53, Issue 23, 1997, Pages 7867-7876

  Kirschning, Andreas ^a   Harders, Jan ^a  

^a CLAUSTHAL UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PYRAN DERIVATIVE; THROMBOXANE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030916615     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00475-4     Document Type: Article

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21. We also prepared the methyl-branched derivatives by reaction of 4a and 4b, respectively, with MeLi and compared the NMR data with those reported in ref. 4b-d.
22. This phenomenon has also been reported for the bulky tert.-butyl, the silyl and stannyl as well as for the 1,3-dithiolane-2-carboxylate group. For configurational and conformational aspects of 1-alkylated 3-uloses refer to refs. 3b, f, g and 5.
23. For the purpose of convenience the carbohydrate numbering is used for pyranones 6a,b-9a,b.
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