Origins of symptoms in heart failure

Cardiovascular Drugs and Therapy

Volumn 11, Issue SUPPL. 1, 1997, Pages 265-272

  Coats, Andrew J S ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Heart failure; Skeletal muscles; Symptoms

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; INOTROPIC AGENT;

ARTICLE; DYSPNEA; EXERCISE; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PERFORMANCE; HEART MUSCLE METABOLISM; HEART OUTPUT; HEMODYNAMICS; HUMAN; LUNG CAPILLARY PRESSURE; LUNG CONGESTION; LUNG EDEMA; MUSCLE ATROPHY; MUSCLE BLOOD FLOW; MUSCLE FATIGUE; MUSCLE METABOLISM; ORAL DRUG ADMINISTRATION; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROGNOSIS; QUALITY OF LIFE; SALT INTAKE; SENSORY NERVE; SKELETAL MUSCLE; SYMPTOM; TRAINING; VASCULAR ENDOTHELIUM; WEIGHT REDUCTION;

CARDIAC OUTPUT; CARDIAC OUTPUT, LOW; CHRONIC DISEASE; EXERCISE; EXERCISE THERAPY; HUMANS; MUSCLE, SKELETAL; PULMONARY VENTILATION; REGIONAL BLOOD FLOW; VENTRICULAR FUNCTION, LEFT;

EID: 0030916188     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007739830030     Document Type: Article

References (65)

1. Clausen JP. Circulatory adjustments to dynamic exercise and effect of physical training in normal subjects and in patients with coronary artery disease. Prog Cardiovasc Dis 1976;18:459-495.
2. Weber KT, Janicki JS, McElroy PA. Determination of aerobic capacity and the severity of chronic cardiac and circulatory failure. Circulation 1987;76:V140-V145.
3. Poole Wilson PA. The origin of symptoms in patients with chronic heart failure. Eur Heart J 1988;9(Suppl H):49-53.
4. Lipkin DP, Canepa Anson R, Stephens MR, Poole Wilson PA. Factors determining symptoms in heart failure: Comparison of fast and slow exercise tests. Br Heart J 1986;55: 439-445.
5. Clark AL, Sparrow JL, Coats AJS. Muscle fatigue and dyspnoea in chronic heart failure: Two sides of the same coin? Eur Heart J 1995;16:49-52.
6. Franciosa JA, Park M, Levine TB. Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure. Am J Cardiol 1981;47:33-39.
7. Gibbs JSR, Keegan J, Wright C, Fox KM, Poole-Wilson PA. Pulmonary artery pressure changes during exercise and daily activities in chronic heart failure. J Am Coll Cardiol 1990;15:52-61.
8. Baker BJ, Wilen MM, Boyd CM, Dinh H, Franciosa JA. Relation of right ventricular ejection fraction to exercise capacity in chronic left ventricular failure. Am J Cardiol 1984;54:596-599.
9. Clark AL, Swan JW, Laney R, Connelly M, Somerville J, Coats AJ. The role of right and left ventricular function in the ventilatory response to exercise in chronic heart failure. Circulation 1994;89:2062-2069.
10. Wilson JR, Martin JL, Ferraro N. Impaired skeletal muscle nutritive flow during exercise in patients with congestive heart failure: Role of cardiac pump dysfunction as determined by the effect of dobutamine. Am J Cardiol 1984;53: 1308-1315.
11. Jondeau G, Katz SD, Zohman L, Goldberger M, McCarthy M, Bourdarias JP, LeJemtel TH. Active skeletal muscle mass and cardiopulmonary reserve. Failure to attain peak aerobic capacity during maximal bicycle exercise in patients with severe congestive heart failure. Circulation 1992;86: 1351-1356.
12. Drexler H, Riede U, Münzel T, König H, Funke E, Just H. Alterations of skeletal muscle in chronic heart failure. Circulation 1992;85:1751-1759.
13. Wilson JR, Mancini DM, Dunkman WB. Exertional fatigue due to skeletal muscle dysfunction in patients with heart failure. Circulation 1993;87:470-475.
14. Poole-Wilson PA. Chronic heart failure: Causes, pathophysiology, prognosis, clinical manifestations, investigations. In: Poole-Wilson PA, ed. Diseases of the Heart. London: Balliere Tindall, 1989;48-57.
15. Zelis R, Nellis SH, Longhurst J, Lee G, Mason DT. Abnormalities in the regional circulations accompanying congestive heart failure. Prog Cardiovasc Dis 1975;18:181-199.
16. Sinoway L, Minotti J, Musch T, Goldner D, Davis D, Leaman D, Zelis R. Enhanced metabolic vasodilation secondary to diuretic therapy in decompensated congestive heart failure secondary to coronary artery disease. Am J Cardiol 1987;60:107-111.
17. Wilson JR, Mancini DM. The mechanism of extertional fatigue in heart failure. Cardioscience 1990;1:13-17.
18. Drexler H, Hayoz D, Munzel T, Just H, Zelis R, Brunner HR. Endothelial function in congestive heart failure. Am Heart J 1993;126:761-764.
19. Mancini DM, Walter G, Reichek N, Lenkinksi R, McCully KK, Mullen JL, Wilson JR. Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation 1992;85:1364-1373.
20. Massie BM, Conway M, Rajagopalan B, et al. Skeletal muscle metabolism during exercise under ischemic conditions in congestive heart failure. Evidence for abnormalities unrelated to blood flow. Circulation 1988;78:320-326.
21. Mancini DM, Schwartz M, Ferraro N, Seestedt R, Chance B, Wilson JR. Effect of dobutamine on skeletal muscle metabolism in patients with congestive heart failure. Am J Cardiol 1990;65:1121-1126.
22. Lipkin DP, Jones DA, Round JM, Poole Wilson PA. Abnormalities of skeletal muscle in patients with chronic heart failure [published errata appear in Int J Cardiol 1988;19:396 and Int J Cardiol 1988;20:161]. Int J Cardiol 1988;18:187-195.
23. Sullivan MJ, Green HJ, Cobb FR. Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure. Circulation 1990;81:518-527.
24. Buller NP, Jones D, Poole-Wilson PA. Direct measurement of skeletal muscle fatigue in patients with chronic heart failure. Br Heart J 1991;65:20-24.
25. Minotti JR, Pillay P, Chang L, Wells L, Massie BM. Neurophysiological assessment of skeletal muscle fatigue in patients with congestive heart failure. Circulation 1992;86: 903-908.
26. Mancini DM, Walter G, Reichek N, Lenkinski R, McCully KK, Mullen JL, Wilson JR. Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation 1992;85:1364-1373.
27. Brunotte F, Thompson CH, Adamopoulos S, et al. Rat skeletal muscle metabolism in experimental heart failure: Effects of physical training. Acta Physiol Scand 1995;154:439-447.
28. Adamopoulos S, Coats AJ, Brunotte F, et al. Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol 1993;21:1101-1106.
29. Swan JW, Walton C, Godsland IF, Clark AL, Coats AJS, Oliver MF. Insulin resistance in chronic heart failure. Eur Heart J 1994;15:1528-1532.
30. Anker SD, Volterrani M, Swan J, Chua TP, Poole-Wilson PA, Coats AJS. Hormonal changes in cardiac cachexia. Circulation 1995;92:I-206-I-207.
31. Volterrani M, Clark AL, Ludman PF, Swan JW, Adamopoulos S, Piepoli M, Coats AJS. Determinants of exercise capacity in chronic heart failure. Eur Heart J 1994;15:801-809.
32. Mancini DM, Ferraro N, Nazzaro D, Chance B, Wilson JR. Respiratory muscle deoxygenation during exercise in patients with heart failure demonstrated with near-infrared spectroscopy. J Am Coll Cardiol 1991;18:492-498.
33. Mancini DM, Henson D, LaManca J, Levine S. Evidence of reduced respiratory muscle endurance in patients with heart failure. J Am Coll Cardiol 1994;24:972-981.
34. Chua TP, Coats AJS. The lungs in chronic heart failure. Eur Heart J 1995;16:882-887.
35. Buller NP, Poole-Wilson PA. Mechanism of the increased ventilatory response to exercise in patients with chronic heart failure. Br Heart J 1990;63:281-283.
36. Clark AL, Poole-Wilson PA, Coats AJS. Relation between ventilation and carbon dioxide production in patients with chronic heart failure. J Am Coll Cardiol 1992;20:1326-1332.
37. Sullivan MJ, Higginbotham MB, Cobb FR. Increased exercise ventilation in patients with chronic heart failure: Intact ventilatory control despite hemodynamic and pulmonary abnormalities. Circulation 1988;77:552-559.
38. Clark A, Coats A. The mechanisms underlying the increased ventilatory response to exercise in chronic stable heart failure. Eur Heart J 1992;13:1698-1708.
39. Piepoli M, Clark AL, Volterrani M, Adamopoulos S, Sleight P, Coats AJS. Contribution of muscle afferents to the hemodynamic, autonomic and ventilatory responses to exercise in patients with chronic heart failure. Effects of physical training. Circulation 1996;93:940-952.
40. Chua TP, Amadi A, Clark AL, Harrington D, Coats AJS. Increased chemosensitivity to hypoxia at rest and during exercise in chronic heart failure. Br Heart J 1995;73 (Suppl 3):26.
41. Liang C-S, Hood WB, Jr. Afferent neural pathway in the regulation of cardiopulmonary responses to tissue hypermetabolism. Circ Res 1976;38:209-214.
42. Clark AL, Piepoli M, Coats AJS. Skeletal muscle and the control of ventilation on exercise: Evidence for metabolic receptors. Eur J Clin Invest 1995;25:299-305.
43. Cohn JN, Archibald DG, Ziesche S, et al. Effect of vasodilator therapy on mortality in chronic congestive heart failure. N Engl J Med 1986;314:1547-1552.
44. The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study. N Engl J Med 1987;316:1429-1435.
45. Cohn JN, Johnson G, Ziesche S, et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 1991;325:303-310.
46. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991;325:293-302.
47. Drexler H, Banhardt U, Meinertz T, Wollschläger H, Lehmann M, Just H. Contrasting peripheral short-term and long-term effects of converting enzyme inhibition in patients with congestive heart failure. A double-blind, placebo-controlled trial. Circulation 1989;79:491-502.
48. Packer M, Carver JR, Rodeheffer RJ, et al. Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. N Engl J Med 1991;325: 1468-1475.
49. Colucci WS, Sonnenblick EH, Adams KF, et al. Efficacy of phosphodiesterase inhibition with milrinone in combination with converting enzyme inhibitors in patients with heart failure. The Milrinone Multicenter Trials Investigators. J Am Coll Cardiol 1993;22:113A-118A.
50. Waagstein F. Beta blockers in heart failure. Cardiology 1993;82 (Suppl 3):13-18.
51. Coats AJS. Exercise rehabilitation in chronic heart failure. J Am Coll Cardiol 1993;22(suppl A):172A-177A.
52. Williams RS. Exercise training of patients with ventricular dysfunction and heart failure. Cardiovasc Clin 1985;15:218-231.
53. Letac B, Cribier A, Desplanches JF. A study of left ventricular function in coronary patients before and after physical training. Circulation 1977;56:375-378.
54. Conn EH, Williams RS, Wallace AG. Exercise responses before and after physical conditioning in patients with severely depressed left ventricular function. Am J Cardiol 1982;49:296-300.
55. Sullivan MJ, Higginbotham MB, Cobb FR. Exercise training in patients with chronic heart failure delays ventilatory anaerobic threshold and improves submaximal exercise performance. Circulation 1989;79:324-329.
56. Sullivan MJ, Higginbotham MB, Cobb FR. Exercise training in patients with severe left ventricular dysfunction: Hemodynamic and metabolic effects. Circulation (1988);78: 506-515.
57. Coats AJS, Adamopoulos S, Meyer TE, Conway J, Sleight P. Effects of physical training in chronic heart failure. Lancet 1990;335:63-66.
58. Koch M, Douard H, Broustet JP. The benefit of graded physical exercise in chronic heart failure. Chest 1992;101: 231S-235S.
59. McAllister RM. Endothelial-mediated control of coronary and skeletal muscle blood flow during exercise: Introduction. Med Sci Sports Exerc 1995;27:1122-1124.
60. Minotti JR, Johnson EC, Hudson TH, et al. Skeletal muscle response to exercise training in congestive heart failure. J Clin Invest 1990;86:751-758.
61. Stratton JR, Dunn JF, Adamopoulos S, Kemp GJ, Coats AJ, Rajagopalan B. Training partially reverses skeletal muscle metabolic abnormalities during exercise in heart failure. J Appl Physiol 1994;76:1575-1582.
62. Hambrecht R, Niebauer J, Fiehn E, et al. Physical training in patients with stable chronic heart failure: Effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscles. J Am Coll Cardiol 1995;25:1239-1249.
63. Mancini DM, Henson D, La Manca J, Donchez L, Levine S. Benefit of selective respiratory muscle training on exercise capacity in patients with chronic congestive heart failure. Circulation 1995;91:320-329.
64. Coats AJ, Adamopoulos S, Radaelli A, et al. Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 1992;85:2119-2131.
65. Davey P, Meyer T, Coats A, Adamopoulos S, Casadei B, Conway J, Sleight P. Ventilation in chronic heart failure: Effects of physical training. Br Heart J 1992;68:473-477.