Synthesis and biological evaluation of 7-hydroxy-3,4-diphenyl-1,2- dihydroisoquinolines as new 4-hydroxytamoxifen analogues

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 5, 1997, Pages 939-943

  Kihara, Masaru ^a   Ikeuchi, Motoki ^a   Yamauchi, Aiko ^a   Nukatsuka, Mamoru ^b   Matsumoto, Hiroshi ^b   Toko, Toshiyuki ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

1,2 Dihydroisoquinoline; Anti proliferative activity; MCF 7 cell; Tamoxifen analogue

Indexed keywords

4 HYDROXYTAMOXIFEN; 7 HYDROXY 3,4 DIPHENYL 1,2 DIHYDROISOQUINOLINE; ISOCARBOSTYRIL DERIVATIVE; TAMOXIFEN; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL STRAIN KB; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA;

EID: 0030913928     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.939     Document Type: Article

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