Single and repeated intravenous toxicity studies of pamiteplase (genetical recombination) in rats and monkeys

Journal of Toxicological Sciences

Volumn 22, Issue 2, 1997, Pages 117-133

  Ishikawa, Atsuko ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Acute toxicity; Laboratory animal; Pamiteplase; Subacute toxicity; Thrombolytic agent; YM866

Indexed keywords

CHOLESTEROL; HEMOGLOBIN; PAMITEPLASE; PHOSPHOLIPID; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; BLOOD CLOTTING TIME; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENETIC RECOMBINATION; HEMATOCRIT; INTRAVENOUS DRUG ADMINISTRATION; LOCOMOTION; MALE; MONKEY; NONHUMAN; RAT; THROMBOCYTE COUNT; TOXICITY TESTING;

ANIMALIA; MACACA FASCICULARIS; SAIMIRI; SCIURIDAE;

EID: 0030913788     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.22.2_117     Document Type: Article

References (2)

1. Bartlett, M. S. (1937): Properties of sufficiency and statistical tests. Proc. Roy. Soc. A., 160, 268-282.
2. Dunnett, C. W. (1955): A multiple comparison procedure for comparing several treatments with a control. J. Am. Statist. Assoc., 50, 1096-1121.