Restricted CDR3 length of the heavy chain is characteristic of six randomly isolated disease-associated V(H) J558+ IgM autoantibodies in lupus prone motheaten mice

International Immunology

Volumn 9, Issue 5, 1997, Pages 655-664

  Lipsanen, V ^a   Walter, B ^a   Emara, M ^a   Siminovitch, K ^b   Lam, J ^a   Kaushik, A ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Autoantibody; Autoantibody structure; B 1 lymphocyte; CDR length; J558 genes; Motheaten mutation; V(H); VDJ rearrangement

Indexed keywords

ARGININE; AUTOANTIBODY; AUTOANTIGEN; CD4 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; MITOGENIC AGENT;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY STRUCTURE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CONTROLLED STUDY; ETIOLOGY; GENE EXPRESSION; GENE INSERTION; HYDROPHILICITY; HYDROPHOBICITY; LUPUS VULGARIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTES; BASE SEQUENCE; DISEASE SUSCEPTIBILITY; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 0030913698     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.5.655     Document Type: Article

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