Interactions of lymphokine-activated killer cells and a549 lung carcinoma nodules maintained in three-dimensional culture

Tumor Biology

Volumn 18, Issue 3, 1997, Pages 135-145

  Gharib, M ^a   Tamboise, E ^b   Tamboise, A ^b   Lievre N ^b   Verola O ^c   Beaupain, R ^b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c SAINT LOUIS HOSPITAL   (France)

Author keywords

Apoptosis; Cocultures; Lung carcinoma nodules; Lymphokine activated killer cells; Necrosis; Proliferation

Indexed keywords

INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 2;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CARCINOMA; LYMPHOKINE ACTIVATED KILLER CELL; NECROSIS; PRIORITY JOURNAL;

EID: 0030913655     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1159/000218024     Document Type: Article

References (26)

1. Rosenberg SA: Lymphokinc-acti-vatcd killer cells: A new approach to immunotherapy of cancer, J Natl Cancer Inst 1985;75:595-603.
2. Ortaldo JR, Mason A, Overton R: Lymphokine-activated killer cells, Analysis of progenitors and effectors, J Exp Med 1986; 164:1193- 1205.
3. Kalland T, Berlfrage H, Bhiladvala P, Hcdlund G: Analysis of murine lymphokine-activated killer (LAK) cell phenomenon: Dissection of effectors and progenitors into NK-likc and T-like cells, J Immunol 1987; 138:3640-3645.
4. Grimm EA, Mazumder A, Zhang HZ, Rosenberg SA: Lymphokinc-ac-tivated killer cell phenomenon: Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes, J Prep Med 1982;155:1823-1841.
5. Kovacs EJ, Beckncr SK, Longo DL, Varcsio L, Young HA: Cytokine gene expression during the generation of human lymphokine-acti-vatcd killer cells: Early induction of interleukin 1 p by interleukin 2, Cancer Res 1989;49:940-944.
6. Masson D, Tschopp J: Isolation of a lytic pore forming protein (perforin) from cytotoxic T lymphocytes, J Biol Chcm 1985;260:9072-9096.
7. Smyth JM, Ortaldo JR, Shinkai Y, Yagita H, Nakata M, Okumura K, Young HA: Interleukin 2 induction of pore forming protein gene expression in human peripheral blood CD8+ T cells, J Exp Med 1990; 171: 1269-1281.
8. Perez C, Albert I, Dctay K, Zachar-iadcs N, Gooding L, Kriegler M: A nonsccrctable cell surface mutant of tumor necrosis factor (TNF) kills by ccll-to-ccll contact, Cell 1990:63: 251-258.
9. Rosenberg SA, Spiess P, Lafrcniere RA: A new approach to the adoptive immunotherapy of cancer with tumor infiltrating lymphocytes, Science 1986;233:1318-1321.
10. Belldegrun A, Muul LM, Rosenberg SA: Interleukin 2 expanded Tumor-infiltrating lymphocytes in human renal cell cancer: Isolation, characteristics, and antitumor activity, Cancer Res 1988;48:206-214.
11. Sutherland RM, Durand RE: Growth and cellular characteristics of multi-cell spheroids; in Acker M, Carlsson J, Durand R, Sutherland RM (eds): Recent Results in Cancer Research, Spheroids in Cancer Research, Berlin, Springer, 1984, vol 95, pp 24-49.
12. Knuchel R, Sutherland RM: Recent developments in research with human tumor spheroids, Cancer J 1990;3:234-243.
13. Jaaskelainen J, Kalliomaki P, Pae-tau A, Timoncn T: Effect of LAK cells against three dimensional tumor tissue, In vitro study using mul-ti-ccllular glioma spheroids as targets, J Immunol 1989; 142:1036- 1045.
14. Beaupain R, Baroche C, Lagarde D: Long-term regeneration of cisplatin-um and X-ray treated human tumor nodules maintained in continuous organotypic culture, Int J Radiat Oncol Biol Phys 1983;9:707-712.
15. Beaupain R, Billard C, Falcoff E: Effects of human recombinant inter-fcron-ob, -p, and -y on growth and survival of human cancer nodules maintained in continuous organotypic culture, Eur J Cancer Clin Oncol 1986;22:141-149.
16. Gharib M, Maingucnc C, Tamboise A, Beaupain R: I.ymphokine-acti-vatcd killer cells induce differentiation in MCF-7 breast carcinoma nodules but not in mastosis nodules maintained in three-dimensional culture, Tumor Biol 1994; 15:90-100.
17. Gharib M, Tamboise E, Tamboise A, Lievre N, Verola O, Beaupain R: Effects of lymphokinc activated killer cells on melanoma nodules maintained in three-dimensional culture, Int J Oncol 1995:7:1327-1332.
18. Hiscrodt JC: Lymphokine activated killer cells: Biology and relevance to disease, Cancer Invest 1993; 11: 420-439.
19. Chevillard S, Beaupain R, Coppcy J: Growth stimulation by misonida-zolc of lung carcinoma cells maintained in continuous organotypic and monolayer cultures, Anticancer Res 1985;5:241-248.
20. Roth MD, Pinto M, Golub S, Shau H: Pulmonary surfactant inhibits interleukin 2 induced proliferation and the generation of lymphokine activated killer cells, Am J Respir Cell Mol Biol 1993;9:652-658.
21. Ogata S, Maimonis PJ, Itzkowitz SH: Mucir.s bearing the cancer-associated sialosyl-Tn antigen mediate inhibition of natural killer cell cytotoxicity, Cancer Res 1992:52:4741-4746.
22. Toledano M, Mathiot C, Michon Y, Andreu G, Lando D, Branely M, Fridman WH: Interferon-y (IFN-y) and intcrleukin-2 in the generation of lymphokine-activated killer cell cytotoxicity, IFN-y induced suppressive activity, Cancer Immunol Immunothcr 1989:30:57-64.
23. Freshney RI: Culture of Animal Cells, A Manual of Basic Technique, New York, Liss, 1987.
24. McGinnes K, Chapman G, Marks R, Penny R: A fluorescence NK assay using flow cytometry, J Immunol 1986;86:7-15.
25. Kasid A, Bell GI, Director EP: Effects of transforming growth factor p on human lymphokinc activated killer cell precursors: Autocrine inhibition of cellular proliferation and differentiation to immune killer cells, J Immunol 1988:141:690-698.
26. Brouty-Boye D, Maingucne C, Mag-nicn V, Israel L, Beaupain R: Fibroblast mediated differentiation in human breast carcinoma cells (MCF-7) grown as nodules in vitro, Int J Cancer 1994;56:731-735.