Carbohydrate supplementation affects blood granulocyte and monocyte trafficking but not function after 2.5 h of running

American Journal of Clinical Nutrition

Volumn 66, Issue 1, 1997, Pages 153-159

  Nieman, David C ^a   Fagoaga, Omar R ^b   Butterworth, Diane E ^b   Warren, Beverly J ^b   Utter, Alan ^b   Davis, J Mark ^b   Henson, Dru A ^b   Nehlsen Cannarella, Sandra L ^b  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b NONE

Author keywords

Carbohydrate beverage supplementation; Cortisol; Glucose; Granulocytes; Immune system; Lymphocytes; Marathon running; Monocytes; Oxidative burst; Phagocytosis; Runners

Indexed keywords

ADULT; ARTICLE; CARBOHYDRATE INTAKE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID BLOOD LEVEL; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; GLUCOSE BLOOD LEVEL; GRANULOCYTE; HUMAN; HUMAN EXPERIMENT; MONOCYTE; NORMAL HUMAN; OXYGEN CONSUMPTION; PHAGOCYTOSIS; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY BURST; RUNNING;

EID: 0030913240     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/66.1.153     Document Type: Article

References (39)

1. Nieman DC, Ahle JC, Henson DA, et al. Indomethacin does not alter natural killer cell response to 2.5 h of running. J Appl Physiol 1995;79:748-55.
2. Nieman DC, Simandle S, Henson DA, et al. Lymphocyte proliferation response to 2.5 hours of running. Int J Sports Med 1995;16:404-8.
3. Nieman DC, Berk LS, Simpson-Westerberg M, et al. Effects of long endurance running on immune system parameters and lymphocyte function in experienced marathoners. Int J Sports Med 1989;10:317-23.
4. Nieman DC, Nehlsen-Cannarella SL. Effects of endurance exercise on immune response. In: Shephard RJ, Åstrand PO, eds. Endurance in sport. Oxford, England: Blackwell Scientific Publications, 1992:487-504.
5. Nieman DC, Henson DA, Butterworth DE, et al. Vitamin C supplementation does not alter the immune response to 2.5 hours of running. Int J Sports Nutr (in press).
6. Berk LS, Nieman DC, Youngberg WS, et al. The effect of long endurance running on natural killer cells in marathoners. Med Sci Sports Exerc 1990;22:207-12.
7. Nieman DC. Prolonged aerobic exercise, immune response, and risk of infection. In: Hoffman-Goetz, ed. Exercise and immune function. Boca Raton, FL: CRC Press, 1996:143-61.
8. Shephard RJ, Shek PN. Heavy exercise, nutrition and immune function: is there a connection? Int J Sports Med 1995;16:491-7.
9. Singh A, Failla ML, Deuster PA. Exercise-induced changes in immune function: effects of zinc supplementation. J Appl Physiol 1994;76:2298-303.
10. Newsholme EA. Biochemical mechanisms to explain immunosuppression in well-trained and overtrained athletes. Int J Sports Med 1994;15(suppl):S142-7.
11. Davis JM, Cokkinides VE, Burgess WA, Bartoli WP. Effects of a carbohydrate-electrolyte drink or water on the stress hormone response to prolonged intense cycling: renin, angiotensin I, aldosterone, ACTH, and cortisol. In: Laron Z, Rogol AD, eds. Hormones and sports. New York: Raven Press, 1989:193-204.
12. MacLaren DP, Reilly T, Campbell IT, Frayn KN. Hormonal and metabolite responses to glucose and maltodextrin ingestion with or without the addition of guar gum. Int J Sports Med 1994;15:466-71.
13. Mitchell JB, Costill DL, Houmard JA, Flynn MG, Fink WJ, Beltz JD. Influence of carbohydrate ingestion on counterregulatory hormones during prolonged exercise. Int J Sports Med 1990;11:33-6.
14. Murray R, Paul GL, Seifert JG, Eddy DE. Responses to varying rates of carbohydrate ingestion during exercise. Med Sci Sports Exerc 1991;23:713-8.
15. Nieman DC, Johanssen LM, Lee JW, Arabatzis K. Infectious episodes in runners before and after the Los Angeles Marathon. J Sports Med Phys Fitness 1990;30:316-28.
16. Peters EM, Goetzsche JM, Grobbelaar B, Noakes TD. Vitamin C supplementation reduces the incidence of postrace symptoms of upper-respiratory-tract infection in ultramarathon runners. Am J Clin Nutr 1993;57:170-4.
17. Woods JA, Davis JM. Exercise, monocyte/macrophage function, and cancer. Med Sci Sports Exerc 1994;26:147-56.
18. Pyne DB. Regulation of neutrophil function during exercise. Sports Med 1994;17:245-58.
19. Ortega E. Physiology and biochemistry: influence of exercise on phagocytosis. Int J Sports Med 1994;15(suppl):S172-8.
20. Macha M, Shlafer M, Kluger MJ. Human neutrophil hydrogen peroxide generation following physical exercise. J Sports Med Phys Fitness 1990;30:412-9.
21. Wong CW, Smith SE, Thong YH, Opdebeeck JP, Thornton JR. Effects of exercise stress on various immune functions in horses. Am J Vet Res 1992;53:1414-7.
22. Cupps TR, Fauci AS. Corticosteroid-mediated immunoregulation in man. Immunol Rev 1982;65:133-55.
23. Bruce RA, Kasumi F, Hosmer D. Maximal oxygen intake and nomographic assessment of functional aerobic impairment in cardiovascular disease. Am Heart J 1973;85:546-62.
24. Pollock ML, Wilmore JH, Fox SM. Exercise in health and disease: evaluation and prescription for prevention and rehabilitation. Philadelphia: WB Saunders Co, 1984;53-87:205-22.
25. Nieman DC, Nehlsen-Cannarella SL, Henson DA, et al. Immune response to obesity and moderate weight loss. Int J Obes 1996;20:353-60.
26. Maruta K, Fujita K, Ito S, Nagatsu T. Liquid chromatography of plasma catecholamines, with electrochemical detection, after treatment with boric acid gel. Clin Chem 1984;30:1271-3.
27. Hyvarinen A, Nikkila EA. Specific determination of blood glucose with o-toluidine. Clin Chim Acta 1962;7:140-3.
28. Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 1974;37:247-8.
29. Belcastro AN, Arthur GD, Albisser TA, Raj DA. Heart, liver, and skeletal muscle myeloperoxidase activity during exercise. J Appl Physiol 1996;80:1331-5.
30. Bury TB, Pirnay F. Effect of prolonged exercise on neutrophil myeloperoxidase secretion. Int J Sports Med 1995;16:410-2.
31. Dufaux B, Order U. Plasma elastase-α1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor after prolonged exercise. Int J Sports Med 1989;10:434-8.
32. Ortega E, Collazos ME, Maynar M, Barriga C, De la Fuente M. Stimulation of the phagocytic function of neutrophils in sedentary men after acute moderate exercise. Eur J Appl Physiol 1993;66:60-4.
33. Smith JA, Gray AB, Pyne DB, Baker MS, Telford RD, Weidemann MJ. Moderate exercise triggers both priming and activation of neutrophil subpopulations. Am J Physiol 1996;270:R838-45.
34. Smith JA, Telford RD, Mason IB, Weidemann MJ. Exercise, training and neutrophil microbicidal activity. Int J Sports Med 1990; 11:179-87.
35. Kokot K, Schaefer RM, Teschner M, Gilge U, Plass R, Heidland A. Activation of leukocytes during prolonged physical exercise. Adv Exp Med Biol 1988;240:57-63.
36. Müns G. Effect of long-distance running on polymorphonuclear neutrophil phagocytic function of the upper airways. Int J Sports Med 1993;15:96-9.
37. Smith JA, Weidemann MJ. The exercise and immunity paradox: a neuro-endocrine/cytokine hypothesis. Med Sci Res 1990;18:749-53.
38. Ortega E, Rodriguez MJ, Barriga C, Forner MA. Corticosterone, prolactin and thyroid hormones as hormonal mediators of the stimulated phagocytic capacity of peritoneal macrophages after high-intensity exercise. Int J Sports Med 1996;17:149-55.
39. Suzuki K, Naganuma S, Totsuka M, et al. Effects of exhaustive endurance exercise and its one-week daily repetition on neutrophil count and functional status in untrained men. Int J Sports Med 1996; 17:205-12.