Lymphomas in Eμ-Pim1 transgenic mice exposed to pulsed 900 MHz electromagnetic fields

Radiation Research

Volumn 147, Issue 5, 1997, Pages 631-640

  Repacholi, Michael H ^a,f   Basten, Antony ^b   Gebski, Val ^b   Noonan, Denise ^c   Finnie, John ^d   Harris, Alan W ^e  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^d Central Veterinary Laboratory   (Australia)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RISK; CARCINOGENESIS; DOSE TIME EFFECT RELATION; ELECTROMAGNETIC FIELD; ELECTROMAGNETIC RADIATION; GENETIC SUSCEPTIBILITY; LONG TERM EXPOSURE; LYMPHOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RISK ASSESSMENT; RISK FACTOR; TRANSGENIC MOUSE;

EID: 0030913092     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579630     Document Type: Article

References (54)

1. NRPB, Electromagnetic Fields and the Risk of Cancer. Report of an Advisory Group on Non-ionising Radiation. HMSO, London, 1992.
2. UNEP/IRPA/WHO, Electromagnetic Fields (300 Hz-300 GHz). Environmental Health Criteria 137, WHO, Geneva, 1993.
3. M. H. Repacholi, M. Grandolfo, A. Ahlbom, U. Bergqvist, J. H. Bernhardt, J. P. Cesarini, L. A. Court, A. F. Mckinlay, D. H. Sliney, J. A. J. Stolwijk, M. L. Swicord, L. D. Szabo, T. S. Tenforde, H. P. Jammet and R. Matthes, Health issues related to the use of hand-held radiotelephones and base transmitters. Health Phys. 70, 587-593 (1996).
4. T. A. Seemayer and W. K. Cavenee, Biology of disease. Molecular mechanisms of oncogenesis. Lab. Invest. 60, 585-599 (1989).
5. T. H. Rabbitts, Chromosomal translocations and human cancer. Nature 372, 143-149 (1994).
6. S. Sarkar, S. Ali and J. Behari, Effect of low power microwave on the mouse genome: A direct DNA analysis. Mutat. Res. 320, 141-147 (1994).
7. H. Lai and N. P. Singh, Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. Bioelectromagnetics 16, 207-210 (1995).
8. S. Szmigielski, A. Szudzinski, A. Pietraszek, M. Bielec, M. Janiak and J. K. Wrembel, Accelerated development of spontaneous and benzopyrene-induced skin cancer in mice exposed to 2450-MHz microwave radiation. Bioelectromagnetics 3, 179-191 (1982).
9. A. Szudzinski, A. Pietraszek, M. Janiak, J. Wrembel, M. Kalczak and S. Szmigielski, Acceleration of the development of benzopyrene-induced skin cancer in mice by microwave radiation. Arch. Dermatol. Res. 274, 302-312 (1982).
10. S. Szmigielski, M. Bielec, S. Lipski and G. Sokolska, Immunologic and cancer-related aspects of exposure to low-level microwave and radiofrequency fields. In Modern Bioelectricity (A. A. Marino, Ed.), pp. 861-925. Marcel Dekker, New York, 1988.
11. R. Y. Wu, H. Chiang, B. J. Shao, N. G. Li and Y. D. Fu, Effects of 2.45-GHz microwave radiation and phorbol ester 12-O-tetradecanoylphorbol-13-acetate on dimethylhydrazine-induced colon cancer in mice. Bioelectromagnetics 15, 531-538 (1994).
12. R. Santini, M. Hosni, P. Deschaux and H. Pacheco, B16 melanoma development in black mice exposed to low-level microwave radiation. Bioelectromagnetics 9, 105-107 (1988).
13. L. G. Salford, A. Brun, B. R. R. Persson and J. Eberhardt, Experimental studies of brain tumour development during exposure to continuous and pulsed 915 MHz radiofrequency radiation. Bioelectrochem. Bioenerget. 30, 313-318 (1993).
14. C-K. Chou, A. W. Guy, L. L. Kunz, R. B. Johnson, J. J. Crowley and J. H. Krupp, Long-term, low-level microwave irradiation of rats. Bioelectromagnetics 13, 469-496 (1992).
15. M. van Lohuizen, S. Verbeek, P. Krimpenfort, J. Domen, C. Saris, T. Radaszkiewicz and A. Berns, Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell 56, 673-682 (1989).
16. M. Breuer, R. Slebos, S. Verbeek, M. van Lohuizen, E. Wientjens and A. Berns, Very high frequency of lymphoma induction by a chemical carcinogen in pim-1 transgenic mice. Nature 340, 61-63 (1989).
17. M. Breuer, E. Wientjens, S. Verbeek, R. Slebos and A. Berns, Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras. Cancer Res. 51, 958-963 (1991).
18. P. K. Pattengale and C. R. Taylor, Experimental models of lympho-proliferative disease: the mouse as a model for human non-Hodgkin's lymphomas and related leukemias. Am. J. Pathol. 113, 237-267 (1983).
19. C. H. Durney, H. Massoudi and M. F. Iskander, Radiofrequency Radiation Dosimetry Handbook, 4th ed. USAFSAM-TR-85-73, USAF School of Aerospace Medicine, Brooks Air Force Base, TX, 1986.
20. V. Anderson and K. H. Joyner, Specific absorption rate levels measured in a phantom head exposed to radio frequency transmissions from analog hand-held mobile phones. Bioelectromagnetics 16, 60-69 (1995).
21. D. A. Hill, Waveguide technique for the calibration of miniature implantable electric-field probes for use in microwave bioeffects studies. IEEE Trans. Microwave Theory Tech. 30, 92-99 (1982).
22. M. S. Pepe, Inference with dependent risks in multiple end-point studies. J. Am. Stat. Assoc. 86, 770-778 (1991).
23. W. R. Rice, A new probability model for determining exact P-values for 2×2 tables when comparing binomial probabilities. Biometrics 44, 1-22 (1988).
24. C. Rowlatt, F. C. Chesterman and M. U. Sheriff, Lifespan, age changes and tumour incidence in an ageing C57BL mouse colony. Lab. Anim. 10, 419-442 (1976).
25. K. Lennert, Malignant Lymphomas Other than Hodgkin's Disease, pp. 107-110. Springer-Verlag, Berlin, 1978.
26. S. E. O'Reilly and J. M. Connors, Non-Hodgkin's lymphoma. I. Characterisation and treatment. Br. Med. J. 304, 1682-1686 (1992).
27. H. M. Kaplan, N. R. Brewer and W. H. Blair, Physiology. In The Mouse in Biomedical Research, Volume III, Normative Biology, Immunology, and Husbandry (H. L. Foster, J. D. Small and J. G. Fox, Eds.), pp. 247-292. Academic Press, New York, 1983.
28. G. S. Edwards, C. C. Davis, J. D. Saffer and M. L. Swicord, Resonant microwave absorption of selected DNA molecules. Phys. Rev. Lett. 53, 1284 (1984).
29. C. Gabriel, E. H. Grant, R. Tata, P. R. Brown, B. Gestblom and E. Noreland, Microwave absorption of aqueous solutions of DNA. Nature 328, 145-146 (1987).
30. C. Gabriel, E. H. Grant, R. Tata, P. R. Brown, B. Gestblom and E. Noreland, Dielectric behavior of aqueous solutions of plasmid DNA at microwave frequencies. Biophys. J. 55, 29-34 (1989).
31. W. R. Adey, Cell membranes: the electromagnetic environment and cancer promotion. Neurochem. Res. 13, 671-677 (1988).
32. W. R. Adey, The extracellular space and energetic hierarchies in electrochemical signalling between cells. In Charge and Field Effects in Biosystems - 2 (M. J. Allen, S. F. Cleary and F. M. Hawkridge, Eds.), pp. 561-580. Plenum Press, New York and London, 1989.
33. W. Stodolnik-Baranska, Lymphoblastoid transformation of lymphocytes in vitro after microwave irradiation. Nature 214, 102-103 (1967).
34. P. E. Hamrick and S. S. Fox, Rat lymphocytes in culture exposed to 2450 MHz (CW) microwave radiation. J. Microwave Power 12, 125-132 (1977).
35. N. J. J. Roberts, S-T. Lu and S. M. Michaelson, Human leukocyte functions and the U.S. safety standard for exposure to radio-frequency radiation. Science 220, 318-320 (1983).
36. N. J. J. Roberts, S. M. Michaelson and S-T. Lu, Mitogen responsiveness after exposure of influenza virus-infected human mononuclear leukocytes to continuous and pulse-modulated radiofrequency radiation. Radiat. Res. 110, 353-361 (1987).
37. R. P. Liburdy and A. Wyant, Radiofrequency and the immune system. Part 3. In vitro effects on human immunoglobulin and on murine T- and B-lymphocytes. Int. J. Radiat. Biol. 46, 67-81 (1984).
38. D. B. Lyle, P. Scheeter, W. R. Adey and R. L. Lundak, Suppression of T-lymphocyte cytotoxicity following exposure to sinusoidally amplitude-modulated fields. Bioelectromagnetics 4, 281-292 (1983).
39. M. F. Sultan, C. A. Cain and W. A. F. Tompkins, Immunological effects of amplitude-modulated radio frequency radiation: B lymphocyte capping. Bioelectromagnetics 4, 157-165 (1983).
40. N. J. J. Roberts, S. M. Michaelson and S-T. Lu, Exposure of human mononuclear leukocytes to microwave energy pulse-modulated at 16 or 60 Hz. IEEE Trans. Microwave Theory Tech. 32, 803 (1984).
41. J. M. Adams and S. Cory, Transgenic models of tumor development. Science 254, 1161-1167 (1991).
42. A. Berns, M. Breuer, S. Verbeek and M. van Lohuizen, Transgenic mice as a means to study synergism between oncogenes. Int. J. Cancer Suppl. 4, 22-25 (1989).
43. J. M. Adams and S. Cory, Oncogene cooperativity in leukemogenesis. Cancer Surveys 15, 119-141 (1992).
44. B. N. Ames and L. S. Gold, Animal cancer tests and cancer prevention. Natl. Cancer Inst. Monogr. 12, 125-132 (1992).
45. B. N. Ames, L. S. Gold and W. C. Willett, The causes and prevention of cancer. Proc. Natl. Acad. Sci. USA 92, 5258-5265 (1995).
46. P. J. Dimbylow, FDTD calculations for a dipole closely coupled to the head at 900 MHz and 1.9 GHz. Phys. Med. Biol. 38, 361-368 (1993).
47. P. J. Dimbylow and S. M. Mann, SAR calculations in an anatomically realistic model of the head for mobile communication receivers at 900 MHz and 1.8 GHz. Phys. Med. Biol. 39, 1537-1553 (1994).
48. H. Rosenbaum, A. W. Harris, M. L. Bath, J. McNeall, E. Webb, J. M. Adams and S. Cory, An Eμ-v-abl transgene elicits plasmacytomas in concert with an activated myc gene. EMBO J. 9, 897-905 (1990).
49. T. C. Wang, R. D. Cardiff, L. Zukerberg, E. Lees, A. Arnold and E. V. Schmidt, Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369, 669-671 (1994).
50. T. Jacks, A. Fazeli, E. M. Schmitt, R. T. Bronson, M. A. Goodell and R. A. Weinberg, Effects of an Rb mutation in the mouse. Nature 359, 295-300 (1992).
51. M. Harvey, M. J. McArthur, C. A. J. Montgomery, J. S. Butel, A. Bradley and L. A. Donehower, Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice. Nat. Genet. 5, 225-229 (1993).
52. T. Jacks, L. Remington, B. O. Williams, E. M. Schmitt, S. Halachmi, R. T. Bronson and R. A. Weinberg, Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4, 1-7 (1994).
53. R. W. Tennant, J. E. French and J. W. Spalding, Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models. Environ. Health Perspect. 103, 942-950 (1995).
54. D. Malkin, F. P. Li, L. C. Strong, J. F. Fraumeni, Jr., C. E. Nelson, D. H. Kim, J. Kassel, M. A. Gryka, F. Z. Bischoff, M. A. Tainsky and S. H. Friend, Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250, 1233-1238 (1990).