Further biochemical and pharmacological characterization of PF-3, a neurotoxic peptide from the 'armed' spider, Phoneutria nigriventer

Journal of Natural Toxins

Volumn 6, Issue 2, 1997, Pages 211-219

  Wolff, P ^a   Troncone, L R ^a   Lebrun, I ^a   Magnoli, F ^a   Raw, I ^a   Ho, P L ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AGELENOPSIS APERTA; ARANEAE; LATICAUDA SEMIFASCIATA; NAJA NIGRICOLLIS; PHONEUTRIA NIGRIVENTER; STAPHYLOCOCCUS PHAGE 3A;

EID: 0030912638     PISSN: 10588108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Adams, M. E., Bindokas, V. P., Hasegawa, L., and Venema, V. (1990). ω-Agatoxins - novel calcium channel antagonists of 2 subtypes from funnel web spider (Agelenopsis aperta) venom. J. Biol. Chem. 265, 861-867.
2. Avidor, T., Clementi, E., Schwartz, L., and Atlas, D. (1994). Caffeine-induced transmitter release is mediated via ryanodine-sensitive channel. Neurosci. Lett. 165, 133-136.
3. Cordeiro, M. N., Figueiredo, S. G., Valentim, A. C., Diniz, C. R., Von Eickstedt, V. R. D., Gilroy, J., and Richardson, M. (1993). Purification and amino acid sequence of six Tx3 type neurotoxins from the venom of the Brazilian "armed" spider Phoneutria nigriventer. Toxicon 31, 35-42.
4. Cordeiro, M. N., Richardson, M., Gilroy, J., Figueiredo, S. G., Beirão, P. S. L., and Diniz, C. R. (1995). Properties of the venom from the South American "armed" spider Phoneutria nigriventer (Keyserking, 1891). J. Toxicol.-Toxin Rev. 14, 309-326.
5. Ducancel, F., Bouchier, C., Tamiya, T., Boulain, J. C., and Ménez, A. (1991). Cloning and expression of cDNAs encoding snake toxins. In: Snake Toxins, A. L. Harvey (Ed.), pp. 385-414. Pergamon Press, New York.
6. Dufton, M. J., and Harvey, A. L. (1989). The long and the short of snake toxins. TiPS 10, 258-259.
7. Ertel, E. A., Warren, V. A., Adams, M. E., Griffin, P. R., Cohen, C. J., and Smith, M. M. (1994). Type III ω-Agatoxins: A family of probes for similar binding sites on L- and N-type calcium channels. Biochemistry 33, 5098-5108.
8. Greene, L. A., and Tischler, A. S. (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
9. Greene, L. A., and Rein, G. (1977). Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheochromocytoma cells. Brain Res. 129, 247-263.
10. Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, New York.
11. Higgins, D. G., Bleasby, A. J., and Fuchs, R. (1992). Clustal V: Improved software for multiple sequence alignment. Comput. Appl. Biosci. 2, 189-191.
12. Ho, P. L., and Raw, I. (1992). Cyclic AmP potentiates bFGF-induced neunte outgrowth in PC12 cells. J. Cell. Physiol. 150, 647-656.
13. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
14. Matsuidara, P. (1987). Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. J. Biol. Chem. 262, 10035-10038.
15. Meunier, J. C., Olsen, R. W., Ménez, A., Framageot, P., Boquet, P., and Changeux, J. P. (1972). Some physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by tritiated α-toxin from Naja nigricollis venom. Biochemistry 11, 1200-1210.
16. Olivera, B. M., Rivier, J., Scott, J. K., Hillyard, D. R., and Cruz, L. J. (1991). Conotoxins. J. Biol. Chem. 266, 22067-22070.
17. Plummer, M. R., Logothetis, D. E., and Hess, P. (1989). Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons. Neuron 2, 1453-1463.
18. Rezende, Jr., L., Cordeiro, M. N., Oliveira, E. B., and Diniz, C. R. (1991). Isolation of neurotoxic peptides from the venom of the "armed" spider Phoneutria nigriventer. Toxicon 29, 1225-1233.
19. Shafer, T. J., and Atchison, W. D. (1991). Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: A model for neurotoxicological studies. Neurotoxicology 12, 473-492.
20. Souccar, C., Gonçalo, M. C., Lapa, A. J., Troncone, L. R. P., Lebrun, I., and Magnoli, F. (1995). Blockage of acetylcholine release at the motor endplate by a polypeptide from the venom of Phoneutria nigriventer. British J. Pharmacol. 116, 2817-2823.
21. Stallcup, W. B. (1979). Sodium and calcium fluxes in a clonal nerve cell line. J. Physiol. (London) 286, 525-540.
22. 2+ channel by nerve growth factor. Brain Res. 341, 381-384.
23. Toll, L. (1982). Calcium antagonists: High affinity binding and inhibition of calcium transport in a clonal cell line. J. Biol. Chem. 257, 13189-13192.
24. Troncone, L. R. P., Lebrun, I., Magnoli, F., and Yamane, T. (1995). Biochemical and pharmacological studies on a lethal neurotoxic polypeptide from Phoneutria nigriventer spider venom. Neurochem. Res. 20, 879-883.
25. 2 from snake venoms. J. Toxicol. - Toxin Rev. 13, 125-177.