Pertussis toxin shows distinct early signalling events in platelet- activating factor-, leukotriene B4-, and C5a-induced eosinophil homotypic aggregation in vitro and recruitment in vivo

Blood

Volumn 89, Issue 12, 1997, Pages 4566-4573

  Teixeira, Mauro M ^a   Giembycz, Mark A ^a   Lindsay, Mark A ^a   Hellewell, Paul G ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; LEUKOTRIENE B4; PERTUSSIS TOXIN; STAUROSPORINE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL KILLING; CELL MIGRATION; ENZYME INHIBITION; ENZYME MODIFICATION; EOSINOPHILIA; IN VIVO STUDY; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; STIMULUS RESPONSE; THROMBOCYTE AGGREGATION;

EID: 0030912222     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.12.4566     Document Type: Article

References (43)

1. Butterworth AE, Thorne KJI: Eosinophils and parasitic diseases, in Smith H, Cook RM (eds): Immunopharmacology of Eosinophils. London, UK, Academic, 1993, p 119
2. Butterfield JH, Leiferman KM: Eosinophil-associated diseases, in Smith H, Cook RM (eds): Immunopharmacology of Eosinophils. London, UK, Academic, 1993, p 152
3. McLaren DJ: Schistosoma mansoni: The Parasite Surface in Relation to Host Immunity. Chichester, UK, Research Studies, 1980
4. Weller PF: The immunobiology of eosinophils. N Engl J Med 324:1110, 1991
5. Djukanovic R, Roche WR, Wilson JW, Beasley CRW, Twentyman OP, Howarth PH, Holgate ST: Mucosal inflammation in asthma. Am Rev Respir Dis 142:434, 1990
6. Teixeira MM, Williams TJ, Au B-T, Hellewell PG, Rossi AG: Characterisation of eosinophil homotypic aggregation. J Leukoc Biol 57:226, 1995
7. Teixeira MM, Rossi AG, Hellewell PG: Adhesion mechanisms involved in C5a-induced eosinophil homotypic aggregation. J Leukoc Biol 59:389, 1996
8. Meurer R, van Riper G, Feeney W, Cunningham P, Hora D, Springer MS, MacIntyre DE, Rosen H: Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1α, or human interleukin 8. J Exp Med 178:1913, 1993
9. Simon SI, Chambers JD, Butcher E, Sklar LA: Neutrophil aggregation is β2-integrin-and L-selectin-dependent in blood and isolated cells. J Immunol 149:2765, 1992
10. Simon SI, Rochon YP, Lynam EB, Smith CW, Anderson DC, Sklar LA: β2-integrin and L-selectin are obligatory receptors in neutrophil aggregation. Blood 82:1097, 1993
11. Giembycz MA: Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma? Biochem Pharmacol 43:2041, 1992
12. Teixeira MM, Williams TJ, Hellewell PG: Mechanisms and pharmacological manipulation of eosinophil accumulation in vivo. Trends Pharmacol Sci 16:418, 1995
13. Teixeira MM, Rossi AG, Giembycz MA, Hellewell PG: Effects of agents which elevate cyclic AMP on eosinophil homotypic aggregation. Br J Pharmacol 118:2099, 1996
14. 111In-eosinophils induced by inflammatory mediators in vivo. Immunology 73:222, 1991
15. Teixeira MM, Rossi AG, Williams TJ, Hellewell PG: Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig. Br J Pharmacol 112:332, 1994
16. Teixeira MM, Hellewell PG: Effect of a 5-lipoxygenase inhibitor, ZM 230487, on cutaneous allergic inflammation in the guinea-pig. Br J Pharmacol 111:1205, 1994
17. Teixeira MM, Hellewell PG: Differential activation of protein kinase C inhibition on PAF-and C5a-induced eosinophil activation. Br J Pharmacol 117:73P, 1996
18. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440, 1985
19. Springer TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 76:301, 1994
20. Wilkinson SE, Hallam TJ: Protein kinase C: Is its pivotal role in cellular activation over-stated. Trends Pharmacol Sci 15:53, 1994
21. Mitsuyama T, Takeshige K, Minakami S: Cyclic AMP inhibits the respiratory burst of electropermeabilized human neutrophils at a downstream site of protein kinase C. Biochem Biophys Acta 1177:167, 1993
22. Thelen M, Peveri P, Kernen P, Von Tscharner V, Walz A, Baggiolini M: Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J 2:2702, 1988
23. 2 and C: Relationship to activation of the NADPH oxidase. Am J Respir Crit Care Med 151:A680, 1995
24. Agarwal DK, ALi N, Numao T: PAF receptors and G-protein in human blood eosinophils and neutrophils. J Lipid Mediators 5:101, 1992
25. Lucy P, Thompson N, Tain M, Solari R, Hide I, Newman TM, Gomperts BD: A survey of GTP-binding proteins and other potential key regulators of exocytotic secretion in eosinophils. Apparent absence of rab3 and vesicle fusion protein homologues. J Cell Sci 108:3547, 1995
26. - currents in Xenopus oocytes. Distinct guanine nucleotide binding properties. J Biol Chem 266:9771, 1991
27. Hepler PJ, Gilman AG: G-proteins. Trends Biochem Sci 17:383, 1992
28. Amatruda TT, Steele DA, Slepak VZ, Simon MI: Gα16, a G protein subunit specifically expressed in hematopoietic cells. Proc Natl Acad Sci USA 88:5587, 1991
29. Wilkie TM, Scherle PA, Strathman MP, Slepa VZ, Simon MI: Characterization of the G-protein α subunits in the Gq class: Expression in murine tissues and in stromal and hematopoietic cell lines. Proc Natl Acad Sci USA 88:10049, 1991
30. Chao W, Olson MS: Platelet-activating factor: Receptors and signal transduction. Biochem J 292:617, 1993
31. 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo. J Immunol 145:2633, 1990
32. 2+, protein kinase C and phospholipases C and D. Biochem J 310:795, 1995
33. Connolly TM, Lawing WJ, Majerus PW: Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity. Cell 46:951, 1986
34. Molina y Vedia LM, Lapetina EG: Phorbol 12,13-dibutyrate and 1-oleoyl-2-acetyldiacylglycerol stimulate inositol trisphosphate dephosphorylation in human platelets. J Biol Chem 261:10493, 1986
35. Ryu SH, Kim UH, Wahl MI, Brown AB, Carpenter G, Huang KP, Rhee SG: Feedback regulation of phospholipase C-β by protein kinase C. J Biol Chem 265:17941, 1990
36. Kroegel C, Chilvers ER, Giembycz MA, Challiss RAJ, Barnes PJ: Platelet-activating factor stimulates a rapid accumulation of inositol (1,4,5)trisphosphate in guinea pig eosinophils: Relationship to calcium mobilization and degranulation. J Allergy Clin Immunol 88:114, 1991
37. Thomas GMH, Geny B, Cockcroft S: Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme. EMBO J 10:2507, 1991
38. Kroegel C, Giembycz MA, Matthys H, Westwick J, Barnes PJ: Modulatory role of protein kinase C on the siganl transduction pathway utilized by platelet-activating factor in eosinophil activation. Am J Respir Cell MoL Biol 11:593, 1994
39. Asano T, Katada T, Gilman AG, Ross EM: Activation of the inhibitory GTP-binding protein, Gi, by β-adrenergic receptors in reconstituted phospholipid vesicles. J Biol Chem 259:9351, 1984
40. Rooney TA, Hager R, Thomas AP: Adrenergic receptor-mediated phospholipase C activation independent of cAMP formation in turkey erythrocytes. J Biol Chem 266:15068, 1991
41. 4 receptors on guinea pig alveolar eosinophils. J Pharmacol Exp Ther 258:784, 1991
42. Dahl R, Venge P, Olsson I: Variations of blood eosinophils and eosinophil cationic protein in serum in patients with bronchial asthma. Allergy 33:211, 1978
43. Murphy CT, Westwick J: Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional response. Biochem J 283:159, 1992