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Volumn 25, Issue 2, 1997, Pages 97-108

Mononuclear cytotoxicity and proliferation towards glucose stimulated rodent pancreatic islet cells

Author keywords

Autoimmunity; Cytotoxicity; IDDM; Islet cells

Indexed keywords

GLUCOSE;

EID: 0030911825     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939708996276     Document Type: Article
Times cited : (5)

References (54)
  • 1
    • 0025836356 scopus 로고
    • The functional state of the beta cells in the pathogenesis of insulin dependent diabetes mellitus
    • Buschard, K. The functional state of the beta cells in the pathogenesis of insulin dependent diabetes mellitus. Autoimmunity 1991; 10: 65-70.
    • (1991) Autoimmunity , vol.10 , pp. 65-70
    • Buschard, K.1
  • 2
  • 3
    • 0025346694 scopus 로고
    • T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
    • Roep, B. O., Arden, S., de Vries, R. R. P., Hutton, J. C. T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins. Nature 1990; 345: 632-634.
    • (1990) Nature , vol.345 , pp. 632-634
    • Roep, B.O.1    Arden, S.2    De Vries, R.R.P.3    Hutton, J.C.4
  • 4
    • 0022574058 scopus 로고
    • Death of beta cell: Homicide or suicide?
    • Botazzo, G. F., Death of beta cell: Homicide or suicide?. Diab. Med. 1986; 3: 119-30.
    • (1986) Diab. Med. , vol.3 , pp. 119-130
    • Botazzo, G.F.1
  • 5
    • 0027819356 scopus 로고
    • Modulation of Antigen Expression in Relation to Intervention Strategies in Type 1 Diabetes
    • Di Mario, U., Dotta, F. Modulation of Antigen Expression in Relation to Intervention Strategies in Type 1 Diabetes. Diab. Metab. Rev. 1993; 9: 245-249.
    • (1993) Diab. Metab. Rev. , vol.9 , pp. 245-249
    • Di Mario, U.1    Dotta, F.2
  • 6
    • 0028095283 scopus 로고
    • Physiologic relevance of heterogeneity in the pancreatic beta-cell population
    • Pipeleers, D., Kiekens, R., Ling, Z., Wilikens, A., Schuit, F. Physiologic relevance of heterogeneity in the pancreatic beta-cell population. Diabetologia 1994; 37 (supplement 2): S57-S64.
    • (1994) Diabetologia , vol.37 , Issue.2 SUPPL.
    • Pipeleers, D.1    Kiekens, R.2    Ling, Z.3    Wilikens, A.4    Schuit, F.5
  • 7
    • 0022414133 scopus 로고
    • Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals
    • Gotfredsen, C. F., Buschard, K., Frandsen, E. K. Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals. Diabetologia 1985; 28: 933-935.
    • (1985) Diabetologia , vol.28 , pp. 933-935
    • Gotfredsen, C.F.1    Buschard, K.2    Frandsen, E.K.3
  • 8
    • 0025472820 scopus 로고
    • Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy
    • Atkinson, M. A., Maclaren, N. K., Luchetta, R. Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy. Diabetes 1990; 39: 933-937.
    • (1990) Diabetes , vol.39 , pp. 933-937
    • Atkinson, M.A.1    Maclaren, N.K.2    Luchetta, R.3
  • 9
    • 0025890960 scopus 로고
    • Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats
    • Gottlieb, P. A., Handler, E. S., Appel, M. C., Greiner, D. L., Mordes, J. P., Rossini, A. A. Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats. Diabetologia 1991; 34: 296-300.
    • (1991) Diabetologia , vol.34 , pp. 296-300
    • Gottlieb, P.A.1    Handler, E.S.2    Appel, M.C.3    Greiner, D.L.4    Mordes, J.P.5    Rossini, A.A.6
  • 10
    • 0026782989 scopus 로고
    • Prevention of adoptive transfer in BB rats by prophylactic insulin treatment
    • Bertrand, S., De Paepe, M., Vigeant, C., Yale, J.-F. Prevention of adoptive transfer in BB rats by prophylactic insulin treatment. Diabetes 1992; 41: 1273-1277.
    • (1992) Diabetes , vol.41 , pp. 1273-1277
    • Bertrand, S.1    De Paepe, M.2    Vigeant, C.3    Yale, J.-F.4
  • 11
    • 0002341977 scopus 로고
    • Insulin injections prevent diabetes in Bio Breeding/Worcester (BB/Wor) rats
    • Like, A. A. Insulin injections prevent diabetes in Bio Breeding/Worcester (BB/Wor) rats. Diabetes 1986; 35 (supplement 1): 74A.
    • (1986) Diabetes , vol.35 , Issue.1 SUPPL.
    • Like, A.A.1
  • 12
    • 0020043403 scopus 로고
    • Insulin treatment improves the spontanous remission of neonatal streptozotocin diabetes in the rat
    • Portha, B., Picon, L. Insulin treatment improves the spontanous remission of neonatal streptozotocin diabetes in the rat. Diabetes 1982; 31: 165-169.
    • (1982) Diabetes , vol.31 , pp. 165-169
    • Portha, B.1    Picon, L.2
  • 13
    • 0025803954 scopus 로고
    • Insulin prevents adoptive cell transfer of diabetes in the autoimmune non-obese diabetic mouse
    • Thivolet, C. H., Goillot, E., Bedossa, P., Durand, A., Bonnard, M., Orgiazzi, J. Insulin prevents adoptive cell transfer of diabetes in the autoimmune non-obese diabetic mouse. Diabetologia 1991; 34: 314-319.
    • (1991) Diabetologia , vol.34 , pp. 314-319
    • Thivolet, C.H.1    Goillot, E.2    Bedossa, P.3    Durand, A.4    Bonnard, M.5    Orgiazzi, J.6
  • 14
    • 0024504171 scopus 로고
    • A randomised trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus
    • Shah, S. C., Malaone, J. I., Simpson, N. E. A randomised trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus. New Eng. J. Med. 1989; 320: 550-554.
    • (1989) New Eng. J. Med. , vol.320 , pp. 550-554
    • Shah, S.C.1    Malaone, J.I.2    Simpson, N.E.3
  • 15
    • 0023909009 scopus 로고
    • Binding of cytoplasmatic islet cell antibodies is blocked by human pancreatic glycolipid extracts
    • Colman, P, G., Nayak, R. C., Campbell, I. L., Eisenbarth, G. S. Binding of cytoplasmatic islet cell antibodies is blocked by human pancreatic glycolipid extracts. Diabetes 1988; 37: 645-652.
    • (1988) Diabetes , vol.37 , pp. 645-652
    • Colman, P.G.1    Nayak, R.C.2    Campbell, I.L.3    Eisenbarth, G.S.4
  • 16
    • 0019286217 scopus 로고
    • Ventromedial hypothalamic lesions increase pancreatic sensitivity to streptozotocin in rats
    • West, D. B., Seino, Y., Woods, S. C., Porte, D. Ventromedial hypothalamic lesions increase pancreatic sensitivity to streptozotocin in rats. Diabetes 1980; 29: 948-951.
    • (1980) Diabetes , vol.29 , pp. 948-951
    • West, D.B.1    Seino, Y.2    Woods, S.C.3    Porte, D.4
  • 18
    • 0023892258 scopus 로고
    • Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific. BB rat monoclonal autoantibody IC2
    • Buschard, K., Brogren, C. H., Røpke, C., Rygaard, J. Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific. BB rat monoclonal autoantibody IC2. APMIS 1988; 96: 342-346.
    • (1988) APMIS , vol.96 , pp. 342-346
    • Buschard, K.1    Brogren, C.H.2    Røpke, C.3    Rygaard, J.4
  • 19
    • 0025279935 scopus 로고
    • Dependence of antigen expression onfunctional state of beta-cells
    • Aaen, K., Rygaard, J., Josefsen, K., et al. Dependence of antigen expression onfunctional state of beta-cells. Diabetes 1990; 39: 697-701.
    • (1990) Diabetes , vol.39 , pp. 697-701
    • Aaen, K.1    Rygaard, J.2    Josefsen, K.3
  • 20
    • 0001433024 scopus 로고
    • B-cell activity regulates the expression of islet antigenetic determinants
    • Appel, M. C., Dotta, F., O'Neil, J. J., Eisenbarth, G. S. B-cell activity regulates the expression of islet antigenetic determinants. Diabetologia 1989; 32: 461A.
    • (1989) Diabetologia , vol.32
    • Appel, M.C.1    Dotta, F.2    O'Neil, J.J.3    Eisenbarth, G.S.4
  • 22
    • 0015073633 scopus 로고
    • Antipancreaticcellular hypersensitivity in diabetes mellitus
    • Nerup, J., Andersen, O. O., 8endixen, G., Egeberg, J., Poulsen, J. E. Antipancreaticcellular hypersensitivity in diabetes mellitus. Diabetes 1971; 20: 424-427.
    • (1971) Diabetes , vol.20 , pp. 424-427
    • Nerup, J.1    Andersen, O.O.2    Endixen, G.3    Egeberg, J.4    Poulsen, J.E.5
  • 23
    • 0026586397 scopus 로고
    • T-lymphocyte lines specific for Glutamic Acid Decarboxylase (GAO) the 64K beta-cell antigen of IDDM
    • Diaz, J.-L., Ways, J., Hammonds, P. T-lymphocyte lines specific for Glutamic Acid Decarboxylase (GAO) the 64K beta-cell antigen of IDDM. Diabetes 1992; 41 118-121.
    • (1992) Diabetes , vol.41 , pp. 118-121
    • Diaz, J.-L.1    Ways, J.2    Hammonds, P.3
  • 24
    • 0025039679 scopus 로고
    • Identification of the 64k autoantigen in insulin-dependent diabetes as the GABA-sythesizing enzyme glutamic acid decarboxylase
    • Backkeskov, S., Aanstoot, H. J., Christgau, S., et al. Identification of the 64k autoantigen in insulin-dependent diabetes as the GABA-sythesizing enzyme glutamic acid decarboxylase. Nature 1990; 347: 151-156.
    • (1990) Nature , vol.347 , pp. 151-156
    • Backkeskov, S.1    Aanstoot, H.J.2    Christgau, S.3
  • 25
    • 0025936419 scopus 로고
    • Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus
    • Michelsen, B. K., Petersen, J. S., Boel, E., Møldrup, A., Dyrberg, T., Madsen, O. D. Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA 1991; 88: 8754-8758.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8754-8758
    • Michelsen, B.K.1    Petersen, J.S.2    Boel, E.3    Møldrup, A.4    Dyrberg, T.5    Madsen, O.D.6
  • 27
    • 0026551285 scopus 로고
    • Expression of the 64 kDa/glutamic acid decarboxylase rat islet cell autoantigen is influenced by the rate of insulin secretion
    • Bjoerk, E., Kaempe, O., Andersson, A., Karlsson, F. A. Expression of the 64 kDa/glutamic acid decarboxylase rat islet cell autoantigen is influenced by the rate of insulin secretion. Diabetologia 1992; 32: 490-493.
    • (1992) Diabetologia , vol.32 , pp. 490-493
    • Bjoerk, E.1    Kaempe, O.2    Andersson, A.3    Karlsson, F.A.4
  • 28
    • 0025331509 scopus 로고
    • Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro
    • Nakamura, N., Woda, B. A., Tafuri, A., et al. Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro. Diabetes 1990; 39: 836-843.
    • (1990) Diabetes , vol.39 , pp. 836-843
    • Nakamura, N.1    Woda, B.A.2    Tafuri, A.3
  • 29
    • 0022878020 scopus 로고
    • Insulin secretory responses of a clonal cell line of simian virus 40 transformed B cells
    • Ashcroft, S. J. H., Hammonds, P., Harrison, D. E. Insulin secretory responses of a clonal cell line of simian virus 40 transformed B cells. Diabetologia 1986; 29: 727-733.
    • (1986) Diabetologia , vol.29 , pp. 727-733
    • Ashcroft, S.J.H.1    Hammonds, P.2    Harrison, D.E.3
  • 30
    • 0025817122 scopus 로고
    • T-cell reactivity to 38 kD insulin-secretory-granulc protein in patients with recent-onset type 1 diabetes
    • Roep, B. O., Kallan, A. A., Hazenbos, W. L., et al. T-cell reactivity to 38 kD insulin-secretory-granulc protein in patients with recent-onset type 1 diabetes. Lancet 1991; 337: 1439-1441.
    • (1991) Lancet , vol.337 , pp. 1439-1441
    • Roep, B.O.1    Kallan, A.A.2    Hazenbos, W.L.3
  • 31
    • 0025993122 scopus 로고
    • The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice
    • Feige, U., Cohen, I. R. The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice. Springer Semin. Immunopathol. 1991; 13: 99-113.
    • (1991) Springer Semin. Immunopathol. , vol.13 , pp. 99-113
    • Feige, U.1    Cohen, I.R.2
  • 32
    • 0026062609 scopus 로고
    • Heat-shock proteins and immunopathology: Regulatory role of heat-shock protein-specific T cells
    • Nomoto, K., Yoshikai, Y. Heat-shock proteins and immunopathology: regulatory role of heat-shock protein-specific T cells. Springer Semin. Immunopathol. 1991; 13: 63-80.
    • (1991) Springer Semin. Immunopathol. , vol.13 , pp. 63-80
    • Nomoto, K.1    Yoshikai, Y.2
  • 33
    • 0026322837 scopus 로고
    • Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein
    • Elias, D., Reshef, T., Birk, O. S., Van der Zee, R., Walker, M. D., Cohen, I. R. Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein. Proc. Natl. Acad. Sci. USA. 1991; 88: 3088-3091.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3088-3091
    • Elias, D.1    Reshef, T.2    Birk, O.S.3    Van Der Zee, R.4    Walker, M.D.5    Cohen, I.R.6
  • 34
    • 0026723044 scopus 로고
    • Beta-cell expression of 65-kDa heat-shock protein mRNA is function- and age-dependent
    • Pedersen, C. R., Josefsen, K., Bock, T., Hansen, S. V., Buschard. K. Beta-cell expression of 65-kDa heat-shock protein mRNA is function- and age-dependent. APMIS 1992; 100: 765-771.
    • (1992) APMIS , vol.100 , pp. 765-771
    • Pedersen, C.R.1    Josefsen, K.2    Bock, T.3    Hansen, S.V.4    Buschard, K.5
  • 35
    • 0025225997 scopus 로고
    • Metabolism and beta-cell function of rat pancreatic islets exposed to human interleukin-1 beta in the presence of a high glucose concentration
    • Sandler, S., Bendtzen, K., Eizirik, D. L., Strandell, E., Welsh, M., Welsh, N. Metabolism and beta-cell function of rat pancreatic islets exposed to human interleukin-1 beta in the presence of a high glucose concentration. Immunology Letters 1990; 26: 245-252.
    • (1990) Immunology Letters , vol.26 , pp. 245-252
    • Sandler, S.1    Bendtzen, K.2    Eizirik, D.L.3    Strandell, E.4    Welsh, M.5    Welsh, N.6
  • 36
    • 0023950085 scopus 로고
    • Culture of mouse pancreatic islets in different glucose concentrations modifies B cell sensitivity to streptozotocin
    • Eizirik, D. L., Strandell, E., Sandler, S. Culture of mouse pancreatic islets in different glucose concentrations modifies B cell sensitivity to streptozotocin. Diabetologia 1988; 31: 168-174.
    • (1988) Diabetologia , vol.31 , pp. 168-174
    • Eizirik, D.L.1    Strandell, E.2    Sandler, S.3
  • 37
    • 0024421432 scopus 로고
    • Interaction of Beta-Cell Activity and IL-1 Concentration and exposure Time in Isolated Rat Islets of Langerhans
    • Palmer, J. P., Helqvist, S., Spinas, G. A., et al. Interaction of Beta-Cell Activity and IL-1 Concentration and exposure Time in Isolated Rat Islets of Langerhans. Diabetes 1989; 38: 1211-1216.
    • (1989) Diabetes , vol.38 , pp. 1211-1216
    • Palmer, J.P.1    Helqvist, S.2    Spinas, G.A.3
  • 40
    • 0022262852 scopus 로고
    • The thymus-dependent immune system in the pathogenesis of type I (insulin-dependent) diabetes mellitus
    • Buschard, K. The thymus-dependent immune system in the pathogenesis of type I (insulin-dependent) diabetes mellitus. Danish Med. Bul. 1985; 32: 139-151.
    • (1985) Danish Med. Bul. , vol.32 , pp. 139-151
    • Buschard, K.1
  • 41
    • 0022975482 scopus 로고
    • Diabetes mellitus in the BB/W rat. Insulitis in pancreatic islet grafts after transplantation in diabetic recipients
    • Weringer, E. J., Like, A. A. Diabetes mellitus in the BB/W rat. Insulitis in pancreatic islet grafts after transplantation in diabetic recipients. AJP 1986; 125: 107-112.
    • (1986) AJP , vol.125 , pp. 107-112
    • Weringer, E.J.1    Like, A.A.2
  • 43
    • 0027078251 scopus 로고
    • Pancreatic Beta Cells in Insulin-Dependent Diabetes
    • Pipeleers, D., Ling, Z. Pancreatic Beta Cells in Insulin-Dependent Diabetes. Diab. Metab. Rev. 1992; 8: 209-227.
    • (1992) Diab. Metab. Rev. , vol.8 , pp. 209-227
    • Pipeleers, D.1    Ling, Z.2
  • 45
    • 0025281303 scopus 로고
    • Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • Miyazaki, J.-I., Araki, K., Yamato, E., et al. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinol. 1990; 127: 126-132.
    • (1990) Endocrinol. , vol.127 , pp. 126-132
    • Miyazaki, J.-I.1    Araki, K.2    Yamato, E.3
  • 46
    • 0022993678 scopus 로고
    • Isolation of rat pancreatic islets by ductal injection of collagenase
    • Sutton, R., Peters, M., McShane, P., Gray, D. W. R., Morris, P. J. Isolation of rat pancreatic islets by ductal injection of collagenase. Transplant 1986; 42: 689-691.
    • (1986) Transplant , vol.42 , pp. 689-691
    • Sutton, R.1    Peters, M.2    McShane, P.3    Gray, D.W.R.4    Morris, P.J.5
  • 47
    • 8244223498 scopus 로고
    • Optimizing fluoroscens activated cell sorting (FACS) of pancreatic endocrine cells
    • Josefsen, K., Hansen, W. A., Kjaer, T. W., et al. Optimizing fluoroscens activated cell sorting (FACS) of pancreatic endocrine cells. Diabetes 1990; 39 suppl 1: 149A.
    • (1990) Diabetes , vol.39 , Issue.1 SUPPL.
    • Josefsen, K.1    Hansen, W.A.2    Kjaer, T.W.3
  • 48
    • 0029916736 scopus 로고    scopus 로고
    • Flourescence-activated cell sorted rat islet cells and studies of the insulin secretory process
    • Josefsen, K., Stenvang, J.-P., Kindmark, H., et al. Flourescence-activated cell sorted rat islet cells and studies of the insulin secretory process. J. Endocrinol. 1996; 149: 145-154.
    • (1996) J. Endocrinol. , vol.149 , pp. 145-154
    • Josefsen, K.1    Stenvang, J.-P.2    Kindmark, H.3
  • 49
    • 0020700755 scopus 로고
    • Immune islet killing mechanisms associated with insulin-dependent diabetes: In vitro expression of cellular and antibody-mediated islet cell cytotoxicity in humans
    • Charles, A. M., Suzuki, M., Waldeck, N., et al. Immune islet killing mechanisms associated with insulin-dependent diabetes: in vitro expression of cellular and antibody-mediated islet cell cytotoxicity in humans. J. Immunol. 1983; 130: 1189-94.
    • (1983) J. Immunol. , vol.130 , pp. 1189-1194
    • Charles, A.M.1    Suzuki, M.2    Waldeck, N.3
  • 50
    • 0026033901 scopus 로고
    • Abnormal sensitivity to glucose of human islets cultured in a high glucose medium: Partial reversibility after an additional culture in a normal glucose medium
    • Davalli, A. M., Ricordi, C., Socci, C., et al. Abnormal sensitivity to glucose of human islets cultured in a high glucose medium: partial reversibility after an additional culture in a normal glucose medium. J. Clin. Endocrin. Metab. 1991; 72: 202-208.
    • (1991) J. Clin. Endocrin. Metab. , vol.72 , pp. 202-208
    • Davalli, A.M.1    Ricordi, C.2    Socci, C.3
  • 51
    • 0026607455 scopus 로고
    • Human islets chronically exposed in vitro to different stimuli become unresponsive to the same stimuli given acutely: Evidence supporting specific desensitization rather than beta-cell exhaustion
    • Davalli, A. M.. Pontirollo, A. E., Socci, C., et al. Human islets chronically exposed in vitro to different stimuli become unresponsive to the same stimuli given acutely: Evidence supporting specific desensitization rather than beta-cell exhaustion. J. Clin. Endocrin. Metab. 1992; 74: 790-794.
    • (1992) J. Clin. Endocrin. Metab. , vol.74 , pp. 790-794
    • Davalli, A.M.1    Pontirollo, A.E.2    Socci, C.3
  • 52
    • 0026463733 scopus 로고
    • The differentiation of the immune system towards anti-islet autoimmunity. Clinical prospects
    • Boitard, C. Review. The differentiation of the immune system towards anti-islet autoimmunity. Clinical prospects. Diabetologia 1992; 35: 1101-1112.
    • (1992) Diabetologia , vol.35 , pp. 1101-1112
    • Boitard, C.1
  • 54
    • 0024448271 scopus 로고
    • High-Glucose Stimulation of 64,00-Mr Islet Cell Autoantigen Expression
    • Kæmpe, O., Andersson, A., Bjørk, E., Hallberg, A., Karlsson, F. A. High-Glucose Stimulation of 64,00-Mr Islet Cell Autoantigen Expression. Diabetes 1989; 38: 1326-1328.
    • (1989) Diabetes , vol.38 , pp. 1326-1328
    • Kæmpe, O.1    Andersson, A.2    Bjørk, E.3    Hallberg, A.4    Karlsson, F.A.5


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