The cardiovascular response to medullary cholinergic and corticoid stimulation is calcium channel dependent in rats

Blood Pressure

Volumn 6, Issue 3, 1997, Pages 171-179

  Zhu, Da Nian ^a   Xie, Gui Zhen ^a   Li, Peng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

acetylcholine; blood pressure; calcium channel; corticoid; heart rate; medulla oblongata

Indexed keywords

ACETYLCHOLINE; ALDOSTERONE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; CHOLINESTERASE INHIBITOR; CORTICOSTEROID; CORTICOSTERONE; PHYSOSTIGMINE; POTASSIUM FERRICYANIDE; SODIUM CHLORIDE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RESPONSE; CHOLINERGIC STIMULATION; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG MECHANISM; FEMALE; HEART RATE; INTRAPERITONEAL DRUG ADMINISTRATION; INTRASPINAL DRUG ADMINISTRATION; MALE; MEDULLA OBLONGATA; MICROINJECTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT;

EID: 0030911646     PISSN: 08037051     EISSN: None     Source Type: Journal    
DOI: 10.3109/08037059709061934     Document Type: Article

References (32)

1. Brezenoff HE. Brain acetylcholine and hypertension: a compelling association. Trends Auton Pharmacol 1986; 3: 203-12.
2. Zhu DN, Guo XQ, Li P. Relationship between the rostral medullary cholinergic mechanism and the cardiovascular components of the defense reaction. Chin J Physiol Sci 1990; 6: 86-94.
3. Zhu DN, Guo XQ, Li P. Influence of hypothalamic or superficial peroneal nerve stimulation on the release of intracerebral acetylcholine. Chin J Physiol Sci 1991; 7: 18-26.
4. Lin Q, Li P. Rostral medullary cholinergic mechanisms and chronic stress-induced hypertension. J Auton Nerv Syst 1990; 31: 211-8.
5. Lin Q, Li P. Microinjection of scopolamine into the rostral ventrolateral medulla blocks the defense reaction and chronic stress-induced hypertension. Chin J Physiol Sci 1992; 8: 141-9.
6. Zhu DN, Cao QY, Qian ZW, Li P. The changes of plasma concentrations of corticosterone, glucose and lipids in the stress-induced hypertensive rat. Chin J Physiol Sci 1994; 10: 146-54.
7. Zhu DN, Xue LM, Li P. Cardiovascular effects of micro-injection of corticoids and antagonists into the rostral ventrolateral medulla in rats. Blood Pressure 1995; 4: 55-62.
8. Zhu DN, Xue LM, Li P. Effect of central muscarine receptor blockade with DKJ-21 on the blood pressure and heart rate in stress-induced hypertensive rats. 1996; 5: 170-7.
9. Wheeler DB, Sather WA, Randall A, et al. Distinctive properties of a neuronal calcium channel and its distribution to excitatory synaptic transmission in the central nervous system. Adv Second Messenger Phosphoprotein Res 1994; 29: 155-71.
10. Hedlund B, Lorentz M, Arhem P. Muscarinic receptors activate calcium channels and calcium dependent potassium channels in NIE-115 neuroblastoma cells. Parmacol Toxicol 1987; 60: 156-60.
11. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. 2nd ed. Sydney, Orlando, San Diego, New York, Austin, London, Montreal, Tokyo, Toronto: Academic Press, 1986.
12. Sundaram K, Krieger AJ, Sapru H. M-muscarinic receptors mediate pressor responses to cholinergic agonists in the ventrolateral medullary pressor area. Brain Res 1988; 449: 141-9.
13. Sundaram K, Sapru H. Cholinergic nerve terminals in the ventrolateral medullary pressor area: pharmacological evidence. J Auton Nerv Syst 1988; 22: 221-8.
14. Peralta EG, Ashkenazi A, Winslow JW, et al. Distinct primary structure, ligand-binding properties and tissue specific expression of four human muscarinic acetylcholine receptors. EMBO J 1987; 6: 3923-9.
15. Parkinson D. Cholinergic receptors. In: Loewy, Spyer KM, editors. Central regulation of autonomic function. Oxford: Oxford University Press, 1990. 29-43.
16. Matsuzawa H, Nirenberg M. Receptor mediated shifts in cAMP and cGMP in neuroblastoma cells. Proc Natl Acad Sci 1975; 72: 3472-6.
17. Bartfai T, Study RE, Greengard P. Muscarinic receptors and cGMP synthesis. In: Jenden DJ, editor. Cholinergic mechanisms and psychopharmacology. New York: Plenum Press, 1977; 285-95.
18. Bartfai T, Breakefield XO, Greengard P. Regulation of synthesis of guanosine 3′:5′-cyclic monophosphate in neuroblastoma cells. Biochem J 1978; 176: 119-27.
19. Study RE, Breakefield XO, Bartfai T, et al. Voltage-sensitive calcium channels regulate guanosine 3′,5′-cyclic monophosphate level in neuroblastoma cells. Proc Natl Acad Sci 1978; 75: 6295-9.
20. Sharma RK, Kalra J. Molecular interaction between cAMP and calcium channel in calmodulin-dependent cyclic nucleotide phosphodiesterase system. Clin Invest Med 1994; 17: 374-82.
21. Hille B. Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 1994; 17: 531-6.
22. Furuichi T, Mikoshiba K. Inositol 1, 4, 5-trisphosphate receptor-mediated Ca signaling in the brain. J Neurochem 1995; 64: 953-60.
23. Cohen NM, Schmidt DM, McGlennen RC, et al. Receptor-mediated increases in phosphatidylinositol turnover in neuron-like cell lines. J Neurochem 1983; 40: 547-54.
24. Kuba K, Koketsu K. Synaptic events in sympathetic ganglia. Progr Neurobiol 1978; 11: 77-169.
25. Hartzell HC. Mechanisms of slow postsynaptic potential. Nature 1981; 291: 539-44.
26. Towle AC, Sze PY. Steroid binding to synaptic plasma membrane: differential binding of glucocorticoids and gonadal steroids. J Steroid Biochem 1983; 18: 135-43.
27. Hua SY, Chen YZ. Membrane receptor-mediated electrophysiological effects of glucocorticoid on mammalian neurons. Endocrinol 1989; 124: 687-91.
28. Rosner W. The functions of corticosteroid-binding globulin and sex hormone-binding globulin: recent advances. Endocrinol Rev 1990; 11: 80-90.
29. Song LN. Rapid membrane effects of steroid hormones on neurons. Progr Physiol Sci 1992; 23: 204-8 (in Chinese).
30. 125I-bovine serum albumin as a ligand. J Neurochem 1990; 54: 467-72.
31. Chen YZ, Fu H, Guo Z. Membrane receptor for glucocorticoids in mammalian neurons. Methods Neurosci 1993; 11: 16-28.
32. Landfield PW, et al. Evolving aspects of the glucocorticoid hypothesis of brain aging: hormonal modulation of neuronal calcium homeostasis. Neurobiol Aging 1994; 15: 579-88.