Diurnal trends in responses of blood plasma concentrations of glucose, insulin, and C-peptide following high- and low-fat meals and their relation to fat metabolism in healthy middle-aged volunteers

British Journal of Nutrition

Volumn 77, Issue 4, 1997, Pages 523-535

  Frape, David L ^a   Williams, Norman R ^b   Scriven, A J ^b   Palmer, Christopher R ^c   O'Sullivan, Kathryn ^d   Fletcher, Reginald J ^d  

^a The Priory   (United Kingdom)

^b PAPWORTH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d Kellogg Co of Great Britain Ltd   (United Kingdom)

Author keywords

Dietary carbohydrate; Dietary fat; Diurnal change; Insulin; Plasma

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN;

ADULT; ARTICLE; CARBOHYDRATE INTAKE; CIRCADIAN RHYTHM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FAT INTAKE; FEMALE; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; LIPID METABOLISM; MALE; NORMAL HUMAN; TIME;

BLOOD GLUCOSE; C-PEPTIDE; CHOLESTEROL; CIRCADIAN RHYTHM; DIETARY CARBOHYDRATES; DIETARY FATS; FEMALE; HUMANS; INSULIN; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD; TRIGLYCERIDES;

EID: 0030911186     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN19970054     Document Type: Article

References (17)

1. Altman, D. G. (1991). Practical Statistics for Medical Research. London: Chapman and Hall.
2. Baggio, G., Fellin, R., Baiocchi, M. R., Martini, S., Baldo, G., Manzato, E. & Crepaldi, G. (1980). Relationship between triglyceride-rich lipoprotein (chylomicrons and VLDL) and HDL2 and HDL3 in the post-prandial phase in humans. Atherosclerosis 37, 271-276.
3. Barbagallo, C. M., Averna, M. R., Amato, S., Davi, G., Pagano, D., Noto, D. & Notarbartolo, A. (1991). Lipid and apoprotein behaviour after an oral fat load in hypertriglyceridaemia. Diabetes Metabolism 17, 512-519.
4. Chen, Y.-D. I., Swami, S., Skowronski, R., Coulston, A. & Reaven, G. M. (1993). Differences in postprandial lipemia between patients with normal glucose tolerance and noninsulin-dependent diabetes mellitus. Journal of Clinical Endocrinology and Metabolism 76, 172-177.
5. Ferrannini, E., Barrett, E. J., Bevilacqua, S. & DeFronzo, R. A. (1983). Effect of fatty acids on glucose production and utilization in man. Journal of Clinical Investigation 72, 1737-1747.
6. Frape, D. L. & Jones, A. M. (1995). Chronic and postprandial responses of plasma insulin, glucose and lipids in volunteers given dietary fibre supplements. British Journal of Nutrition, 73, 733-751.
7. Frape, D. L., Williams, N. R., Pickersgill, J., Murrills, R., Palmer, C. & Fletcher, R. J. (1994). The postprandial response to high-fat, low-carbohydrate and low-fat, high-carbohydrate meals providing the same amounts of energy in subjects at risk of heart disease. Proceedings of the Nutrition Society, 53, 221A.
8. Guyton, A. C. & Hall, J. E. (1996). Textbook of Medical Physiology, 9th ed., p. 942. Philadelphia: W.B. Saunders Company.
9. Jones, D. B., Patel, S., Slaughter, P., Carter, R. D., Mann, J. I. & Hockaday, T. D. (1984). A comparison of isocaloric high carbohydrate and high fat test meals in diabetics. Postgraduate Medical Journal 60, 129-131.
10. Ohlson, L. O., Bjuro, T., Larsson, B., Eriksson, H., Svardsudd, D., Welin, L. & Wilhelmsen, L. (1989). A cross-sectional analysis of glucose tolerance and cardiovascular disease in 67-year-old men. Diabetic Medicine 6, 112-120.
11. Randle, P. J., Garland, P. B., Hales, C. N. & Newsholme, E. A. (1963). The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1, 785-789.
12. Sidery, M. B., Gallen, I. W. & MacDonald, I. A. (1990). The initial physiological responses to glucose ingestion in normal subjects are modified by a 3 d high-fat diet. British Journal of Nutrition 64, 705-713.
13. Smith, U. (1994). Carbohydrates, fat, and insulin action. American Journal of Clinical Nutrition 59, Suppl., 686S-689S.
14. Svedberg, J., Björntorp, P., Lönnroth, P. & Smith, U. (1991). Prevention of inhibitory effect of free fatty acids on insulin binding and action in isolated rat hepatocytes by Etomoxir. Diabetes 40, 783-786.
15. Svedberg, J., Björntorp, P., Smith, U. & Lönnroth, P. (1990). Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes 39, 570-574.
16. Van Cauter, E., Blackman, J. D., Roland, D., Spire, J.-P., Refetoff, S. & Polonsky, K. S. (1991). Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. Journal of Clinical Investigation 88, 934-942.
17. Van Cauter, E., Shapiro, E. T., Tillil, H. & Polonsky, K. S. (1992). Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythm. American Journal of Physiology 262, E467-E475.