Impaired healing of gastric lesions in streptozotocin-induced diabetic rats: Effect of basic fibroblast growth factor

Journal of Pharmacology and Experimental Therapeutics

Volumn 281, Issue 1, 1997, Pages 200-207

  Takeuchi, Koji ^a   Takehara, Koji ^a   Tajima, Kimihito ^a   Kato, Shinichi ^a   Hirata, Takuya ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL MODEL; ARTICLE; DRUG EFFECT; GLUCOSE BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STOMACH ACID SECRETION; STOMACH EMPTYING; WOUND HEALING;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; FIBROBLAST GROWTH FACTOR 2; GASTRIC ACID; GASTRIC MUCOSA; INSULIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RNA, MESSENGER; STREPTOZOCIN; WOUND HEALING;

EID: 0030910972     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. BELAI, A., LEFEBVRE, R. A. AND BURNSTOCK, G.: Motor activity and neurotransmitter release in the gastric fundus of streptozotocin-diabetic rats. Eur. J. Pharmacol. 194: 225-234, 1991.
2. CORDON-CARDO, C., VLODAVSKY, I., HAIMOVITY-FRIEDMAN, A., HICKLIN, D. AND FUKS, Z.: Expression of basic fibroblast growth factor in normal human tissues. Lab. Invest. 63: 832-840, 1990.
3. DUNNETT, C. W.: A multiple comparison procedure for comparing several treatments with a control. Am. J. Stat. Assoc. 50: 1096-1121, 1955.
4. ENSER, M. AND AVERY, N. C.: Mechanical and chemical properties of the skin and its collagen from lean and obese-hyperglycemic (ob/ob) mice, Diabetologia 27: 44-49, 1984.
5. FAGIN, J. A., ROBERTS, C. T., LEROITH, D. AND BROWN, A. T.: Coordinate decrease of tissue insulin like growth factor 1 posttranscriptional alternative mRNA transcripts in diabetes mellitus. Diabetes 38: 428-434, 1989.
6. FELDMAN, M., CORBETT, D. B., RAMSEY, E. J., WALSH, J. H. AND RICHARDSON, C. T.: Abnormal gastric function in longstanding, insulin-dependent diabetic patients. Gastroenterology 77: 12-17, 1979.
7. FOLKMAN, J. AND KLAGSBRUN, M.: Angiogenic factors. Science 235: 442-447, 1987.
8. FOLKMAN, J., SZABO, S., STROVROFF, M., MCNEIL, P., LI, W. AND SHING, Y.: Duodenal ulcer: Discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann. Surg. 214: 414-427, 1991.
9. GOLDENRING, J. R., TSUNODA, Y., STOCK, S. A., COFFEY, R. J. AND MODLIN, I. M.: Transforming growth factor-alpha (TGF alpha) inhibition of parietal cell secretion: Structural requirements for activity. Regul. Pept. 43: 37-47, 1993.
10. GOODSON, W. H. AND HUNT, T. K.: Wound collagen accumulation in obese hyperglycemic mice. Diabetes 35: 491-495, 1986.
11. HALTER, F., BARBEZAT, G. O., VAN HOORN-HICKMAN, R. AND VAN HOORN, W. A.: Healing dynamics of traumatic gastric mucosal defects in normal and hyperacid stomach. Dig. Dis. Sci. 25: 916-920, 1980.
12. KAMADA, T., KAWANO, S., SATO, N., FUKUDA, M., FUSAMOTO, H. AND ABE, H.: Gastric mucosal blood distribution and its changes in the healing process of gastric ulcer. Gastroenterology 84: 1541-1546, 1983.
13. KARPEN, C. W., SPANHEIMER, R. G., RANDOLPH, A. L. AND LOWE, W. L.: Tissue-specific regulation of basic fibroblast growth factor mRNA levels by diabetes, Diabetes 41: 222-226, 1992.
14. KLINGBEIL, C. K., CESAR, L. B. AND FIDDES, J. C.: Basic fibroblast growth factor accelerates tissue repair in models of impaired wound healing. In Clinical and Experimental Approaches to Dermal and Epidermal Repair: Normal and Chronic Wounds, Wileys-Lias, Inc., 1991, pp. 449-458.
15. MCGEE, G. S., DAVIDHON, J. M., BUCKLEY, A., SUMMER, A., WOODWARD, S. C., AQUINO, A. M., BARBOUR, R. AND DEMETRIOU, A. A.: Recombinant basic fibroblast growth factor accelerates wound healing. J. Surg. Res. 45: 145-153, 1988.
16. O'REILLY, D. AND LONG, R. G.: Diabetes and the gastrointestinal tract. Digest. Dis. 5: 57-64, 1987.
17. PAIMELA, H., GODDARD, P. J., CARTER, K., KHAKEE, R., MCNEIL, P. L., ITO, S. AND SILEN, W.: Restitution of frog gastric mucosa in vitro: Effect of basic fibroblast growth factor. Gastroenterology 104: 1337-1345, 1993.
18. PIYACHATRURAWAT, P., POPRASIT, J. AND GLINSUKON, T.: Gastric mucosal secretions and lesions by different doses of streptozotocin in rats. Toxicol. Lett. 55: 21-29, 1991.
19. POLK, W. H., DEMPSEY, P. J., RUSSELL, W. E., BROWN, P. I., BEAUCHAMP, R. D., BARNARD, J. A. AND COFFEY, R. J.: Increased production of transforming growth factor alpha following acute gastric injury. Gastroenterology 102: 1467-1474, 1992.
20. SATOH, H., SHINO, A., INATOMI, N., NAKAGAWA, H., SATO, F., SZABO, S. AND FOLKMAN, J.: Effects of rhbFGF mutein CS23 (TGP-580) on the healing of gastric ulcers induced by acetic acid in rats. Gastroenterology 100: A155, 1991.
21. SENO, M., SASADA, R., IWANE, M., SUDO, K., KUROKAWA, T., ITO, K. AND IGARASHI, K.: Stabilizing basic fibroblast growth factor using protein engineering. Biochem. Biophys. Res. Commun. 151: P701-708, 1988.
22. SZABO, S., FOLKMAN, J., VATTAY, P., MORALES, R. E., PINKUS, G. S. AND KATO, K.: Accelerated healing of duodenal ulcers by oral administration of mutein of fibroblast growth factor in rats. Gastroenterology 106: 1106-1111, 1994.
23. TAKEUCHI, K., KATO, S., TAKEHARA, K., ASADA, Y. AND YASUHIRO, T.: Role of nitric oxide in mucosal blood flow response and healing of HCl-induced lesions in rat stomachs. Digestion 58: 19-27, 1997.
24. TAKEUHI, K., UESHIMA, K., OHUCHI, T. AND OKABE, S.: Induction of gastric lesions and hypo-glycemic response by food deprivation in streptozotocin-diabetic rats. Digest. Dis. Sci. 39: 626-634, 1994a.
25. TAKEUCHI, K., UESHIMA, K., OHUCHI, T. AND OKABE, S.: The role of capsaicin-sensitive sensory neurons in healing of HCl-induced gastric mucosal lesions in rats. Gastroenterology 106: 1524-1532, 1994b.
26. TAKEUCHI, K. AND JOHNSON, L. R.: Effect of cell proliferation on healing of gastric and duodenal ulcers in rats. Digestion 33: 916-920, 1986.
27. TARNAWSKI, A. AND HALTER, F.: Cellular mechanisms, interactions, and dynamics of gastric ulcer healing. J. Clin. Gastroenterol. 21(Suppl.): S93-S97, 1995.
28. TSUNODA, Y., MODLIN, I. M. AND GOLDENRING, J. R.: Tyrosine kinase activities in the modulation of stimulated parietal cell acid secretion. Am. J. Physiol. 264: G351-G356, 1993.
29. WANG, L., LUCEY, M. R., FRAS, A. M., WILSON, E. J. AND DEL VALLE, J.: Epidermal growth factor and transforming growth factor-alpha directly inhibit pariental cell function through a similar mechanism. J. Pharmacol. Exp. Ther. 265: 308-313, 1993.
30. WATANABE, H., HORI, A., SEND, M., KOZAI, Y., IGARASHI, K., ICHIMORI, Y. AND KONDO, K.: A sensitive enzyme immunoassay for human basic fibroblast growth factor. Biochem. Biophys. Res. Commun. 175: 229-235, 1991.