Effects of nitric oxide synthesis inhibition on mesenteric perfusion in young pigs

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 3 35-3, 1997, Pages

  Alemany, Carlos A ^a   Oh, William ^a   Stonestreet, Barbara S ^a,b  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

blood flow; endothelial relaxing factor; feeding; gastrointestinal tract; intestine; L arginine; N(G) monomethyl L arginine

Indexed keywords

ARGININE; ENDOTHELIUM DERIVED RELAXING FACTOR; N(G) METHYLARGININE; NITRIC OXIDE; WATER;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL GAS; ARTERIAL PH; ARTERIAL PRESSURE; ARTERY BLOOD FLOW; ARTERY PERFUSION; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DIET RESTRICTION; ENTERIC FEEDING; HEMATOCRIT; HYPEREMIA; INTRAARTERIAL DRUG ADMINISTRATION; MESENTERIC ARTERY; MILK; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; SWINE;

EID: 0030910733     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.3.g612     Document Type: Article

References (32)

1. Berman, W., Jr., R. C. Goodlin, M. A. Heymann, and A. M. Rudolph. Measurement of umbilical blood flow in fetal lambs in utero. J. Appl. Physiol. 39: 1056-1059, 1975.
2. Boeckxstaens, G. E., P. A. Pelckmans, I. F. Ruytjens, H. Bult, J. G. DeMan, A. G. Herman, and Y. M. VanMaercke. Bioassay of nitric oxide released upon stimulation of non-adrenergic non-cholinergic nerves in the canine ileocolonic junction. Br. J. Pharmacol. 103: 1085-1091, 1991.
3. Bredt, D. S., and S. H. Snyder. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA 87: 682-685, 1990.
4. Chou, C. C., A. Alemayehu, and M. J. Mangino. Prostanoids in regulation of postprandial jejunal hyperemia and oxygen uptake. Am. J. Physiol. 257 (Gastrointest. Liver Physiol. 20): G798-G808, 1989.
5. 2 receptors in postprandial intestinal hyperemia. Am. J. Physiol. 243 (Gastrointest. Liver Physiol. G): G248-G252, 1982.
6. Crissinger, K. D., and D. L. Burney. Postprandial hemodynamics and oxygenation in developing piglet intestine. Am. J. Physiol. 260 (Gastrointest. Liver Physiol. 23): G951-G957, 1991.
7. G-monomethyl-L-arginine on endothelium-dependent relaxations in the perfused mesenteric vascular bed of the rat. Biochem. Biophys. Res. Commun. 169: 873-879, 1990.
8. Furchgott, R. F., and J. V. Zawadski. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (Lond.) 288: 373-376, 1980.
9. Gallavan, R. H., Jr., and C. C. Chou. Possible mechanisms for the initiation and maintenance of postprandial intestinal hyperemia. Am. J. Physiol. 249 (Gastrointest. Liver Physiol. 12): G301-G308, 1985.
10. Gallavan, R. H., Jr., and C. C. Chou. Prostaglandin synthesis inhibition and postprandial intestinal hyperemia. Am. J. Physiol. 242 (Gastrointest. Liver Physiol. 5): G140-G146, 1982.
11. G-nitro-L-arginine methyl ester in conscious Long-Evans rats. Br. J. Pharmacol. 101: 625-631, 1990.
12. Granger, D. N., P. D. Richardson, P. R. Kvietys, and N. A. Mortillaro. Intestinal blood flow. Gastroenterology 78: 837-863, 1980.
13. Ignarro, L. J. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ. Res. 65: 1-21, 1989.
14. Ignarro, L. J., J. B. Adams, P. M. Horwitz, and K. S. Wood. Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-deficient forms. J. Biol. Chem. 261: 4997-5002, 1986.
15. Kvietys, P. R., R. P. Pittman, and C. C. Chou. Contribution of luminal concentration of nutrients and osmolality to postprandial intestinal hyperemia in dogs. Proc. Soc. Exp. Biol. Med. 152: 659-663, 1976.
16. Martin, W., G. M. Villani, D. Jothianandan, and R. F. Furchgott. Selective blockade of endothelium-dependent and glycerol trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J. Pharmacol. Exp. Ther. 232: 708-716, 1985.
17. Mayfield, S. R., W. Oh, D. L. Piva, and B. S. Stonestreet. Postprandial gastrointestinal blood flow and oxygen consumption during environmental cold stress. Am. J. Physiol. 256 (Gastrointest. Liver Physiol. 19): G364-G368, 1989.
18. Moneta, G. L., D. C. Taylor, W. S. Helton, M. W. Mulholland, and D. E. Strandness, Jr. Duplex ultrasound measurement of postprandial intestinal blood flow: effect of meal composition. Gastroenterology 95: 1294-1301, 1988.
19. Myers, P. R., R. L. Minor, Jr., R. Guerra, Jr., J. N. Bates, and D. G. Harrison. Vasorelaxant properties of endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide. Nature (Lond.) 345: 161-163, 1990.
20. Nankervis, C. A., and P. T. Nowicki. Role of nitric oxide in regulation of vascular resistance in postnatal intestine. Am. J. Physiol. 268 (Gastrointest. Liver Physiol. 31): G949-G958, 1995.
21. Norryd, C., H. Denker, A. Lunderquist, T. Olin, and U. Tylen. Superior mesenteric blood blow during digestion in man. Acta Chir. Scand. 141: 197-202, 1975.
22. Nowicki, P. T., and C. E. Miller. Autoregulation in the developing postnatal intestinal circulation. Am. J. Physiol. 254 (Gastrointest. Liver Physiol. 17): G189-G193, 1988.
23. Nowicki, P. T., and C. E. Miller. Flow-induced dilation in newborn intestine. Pediatr. Res. 38: 783-791, 1995.
24. Nowicki, P. T., B. S. Stonestreet, N. B. Hansen, A. C. Yao, and W. Oh. Gastrointestinal blood flow and oxygen consumption in awake newborn piglets: effect of feeding. Am. J. Physiol. 245 (Gastrointest. Liver Physiol. 8): G697-G702, 1983.
25. Palmer, R. M., D. S. Ashton, and S. Moncada. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature (Lond.) 333: 664-666, 1988.
26. Palmer, R. M., A. G. Ferrige, and S. Moncada. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature (Lond.) 327: 524-526, 1987.
27. 2-receptor vasodilation of canine intestinal circulation. Am. J. Physiol. 233 (Endocrinol. Metab. Gastrointest. Physiol. 2): E219-E224, 1977.
28. Rees, D. D., R. M. Palmer, H. F. Hodson, and S. Moncada. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br. J. Pharmacol. 96: 418-424, 1989.
29. Rees, D. D., R. M. Palmer, and S. Moncada. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. USA 86: 3375-3378, 1989.
30. Rees, D. D., R. M. Palmer, R. Schulz, H. F. Hodson, and S. Moncada. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101: 746-752, 1990.
31. Shepherd, A. P., and G. L. Riedel. Effect of pulsatile pressure and metabolic rate on intestinal autoregulation. Am. J. Physiol. 242 (Heart Circ. Physiol. 11): H769-H775, 1982.
32. Warner, T. D., G. de Nucci, and J. R. Vane. Comparison of the survival of endothelium-derived relaxing factor and nitric oxide within the isolated perfused mesenteric arterial bed of the rat. Br. J. Pharmacol. 97: 777-782, 1989.