Adenosine stimulation of DNA synthesis in human endothelial cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 272, Issue 3 41-3, 1997, Pages

  Ethier, Michael F ^a   Dobson Jr , James G ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

adenosine 5' triphosphate; angiogenesis; phospholipase A2; protein kinase A; protein kinase C; sodium hydrogen exchange

Indexed keywords

ADENOSINE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; PHOSPHOLIPASE A2; PROTEIN KINASE C;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE;

EID: 0030910653     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.272.3.h1470     Document Type: Article

References (44)

1. Adair, T. H., W. J. Gay, and J.-P. Montani. Growth regulation of the vascular system: evidence for a metabolic hypothesis. Am. J. Physiol. 259 (Regulatory Integrative Comp. Physiol. 28): R393-R404, 1990.
2. Adair, T. H., J.-P. Montani, D. M. Strick, and A. C. Guyton. Vascular development in chick embryos: a possible role for adenosine. Am. J. Physiol. 256 (Heart Circ. Physiol. 25): H240-H246, 1989.
3. Auerbach, R. Arigiogenesis-inducing factors: a review. In: Lymphokines, edited by E. Pick. New York: Academic, 1981, p. 69-88.
4. Barrett, K., and T. D. Bigby. Involvement of arachidonic acid in the chloride secretory response of intestinal epithelial cells. Am. J. Physiol. 264 (Cell Physiol. 33): C446-C452, 1993.
5. Bobik, A., A. Grooms, P. J. Little, E. R. Cragoe, and S. Grinpukel. Ethylisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle growth. Am. J. Physiol. 260 (Cell Physiol. 29): C581-C588, 1991.
6. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976.
7. Burnstock, G. A basis for distinguishing two types of purinergic receptor. In: Cell Membrane Receptors for Drugs and Hormones: A Multidisciplinary Approach, edited by L. Bolis and R. N. Straub. New York: Raven, 1978, p. 107-118.
8. 2+-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257: 7847-7851, 1982.
9. Chambard, J. C., S. Paris, G. L'Allemain, and J. Pouysségur. Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin. Nature 326: 800-803, 1987.
10. Chinellato, A., E. Ragazzi, L. Pandolpho, F. Guglielmina, L. Caparrotta, and G. Fassina. Pharmacological characterization of a new purinergic receptor site in rabbit aorta. Gen. Pharmacol. 23: 1067-1071, 1992.
11. 3H]thymidine incorporation does not correlate with growth state in cultured alveolar type II cells. Am. J. Respir. Cell Mol. Biol. 3: 159-164, 1990.
12. Cobb, M. H., T. G. Boulton, and D. J. Robbing. Extracellular signal-regulated kinases: ERKs in progress. Cell Regul. 2: 965-978, 1991.
13. Daly, J. W. Adenosine receptors: targets for future drug use. J. Med. Chem. 25: 197-207, 1982.
14. Dunn, P. M., and A. G. H. Blakeley. Suramin: a reversible P2-purinoceptor antagonist in the mouse vas deferens. Br. J. Pharmacol. 93: 243-245, 1988.
15. Dusseau, J. W., P. M. Hutchins, and D. S. Malbasa. Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane. Circ. Res. 59: 163-170, 1986.
16. Ethier, M. F., V. Chander, and J. G. Dobson, Jr. Adenosine stimulates proliferation of human endothelial cells in culture. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H131-H138, 1993.
17. Fafeur, V., Z. P. Jiang, and P. Bohelen. Signal transduction by bFGF, but not TGFb1, involves arachidonic acid metabolism in endothelial cells. J. Cell. Physiol. 149: 277-283, 1991.
18. Ghai, G., J. E. Francis, M. Williams, R. A. Dotson, M. F. Hopkins, D. T. Cote, F. R. Goodman, and M. B. Zimmerman. Pharmacological characterization of CGS 15943: a novel nonxanthine adenosine antagonist. J. Pharmacol. Exp. Ther. 242: 784-790, 1987.
19. Gopalakrishna, R., Z. H. Chen, and U. Gundimeda. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding. J. Biol. Chem. 268: 27180-27185, 1993.
20. Hagsberg, H., P. Andersson, J. Lacarewicz, I. Jacobson, S. Butcher, and M. Sandberg. Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J. Neurochem. 49: 227-231, 1987.
21. 1 receptor antagonist. Life Sci. 40: 555-561, 1987.
22. Hudlicka, O. Development of microcirculation: capillary growth and adaptation. In: Handbook of Physiology. The Cardiovascular System. Microcirculation. Bethesda, MD: Am. Physiol. Soc., 1984, sect. 2, vol. IV, pt. 1, chapt. 5, p. 165-216.
23. Imai, S., and M. Nakazawa (Editors). Role of Adenosine and Adenine Nucleotides in the Biological System. Amsterdam: Elsevier, 1991, p. 357-515.
24. Jarvis, S. M., L. Sobrevia, and D. L. Yudilevich. Diabetes decreases adenosine transport activity in human endothelial cells (Abstract). Drug Dev. Res. 31: 283, 1994
25. Kornberg, A. DNA Replication. San Francisco, CA: Freeman, 1980, p.89.
26. Li, J. M., R. A. Fenton, B. S. Cutler, and J. G. Dobson, Jr. Adenosine enhances nitric oxide production by vascular endothelial cells. Am. J. Physiol. 269 (Cell Physiol. 38): C519-C523, 1995.
27. Linden, J. Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions. Trends Pharmacol. Sci. 15: 298-306, 1994.
28. Lowenstein, C. J., J. L. Dinerman, and S. H. Snyder. Nitric oxide: a physiologic messenger. Ann. Intern. Med. 120: 227-237, 1994.
29. Lucchesi, P. A., and B. C. Berk. Regulation of sodium-hydrogen exchange in vascular smooth muscle. Cardiovasc. Res. 29: 172-177, 1995.
30. Meek, D. W., and A. J. Street. Nuclear protein phosphorylation and growth control. Biochem. J. 287: 1-15, 1992.
31. Meininger, C. J., and H. J. Granger. Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H198-H206, 1990.
32. Meininger, C. J., M. E. Schelling, and H. J. Granger. Adenosine and hypoxia stimulate proliferation and migration of endothelial cells. Am. J. Physiol. 255 (Heart Circ. Physiol. 24): H554-H562, 1988.
33. Nees, S., M. Bock, V. Herzog, B. F. Becker, C. Des Rosiers, and E. Gerlach. The adenine nucleotide metabolism of the coronary endothelium: implications for the regulation of coronary flow by adenosine. In: Adenosine: Receptors and Modulation of Cell Function, edited by V. Stefanovich, K. Rudolphi, and P. Schubert. Oxford, UK: IRL, 1985, p. 419-436.
34. Nishizawa, N., Y. Okano, Y. Chatani, F. Amano, E. Tanaka, H. Nomoto, Y. Nozwas, and M. Kohno. Mitogenic signaling of growth factors can be distinguished by the involvement of pertussis toxin-sensitive guanosine triphosphate-binding protein and protein kinase C. Cell Regul. 1: 747-761, 1990.
35. O'Connor, S. E., I. A. Dainty, and P. Leff. Further subclassification of ATP receptors based on agonist studies. Trends Pharmacol. Sci. 12: 137-141, 1991.
36. Ontyd, J., and J. Schrader. Measurement of adenosine, inosine and hypoxanthine in human plasma. J. Chromatogr. 307: 404-409, 1984.
37. Pardee, A. B., D. L. Coppock, and H. C. Yang. Regulation of cell proliferation at the onset of DNA synthesis. J. Cell Sci. Suppl. 4: 171-180, 1986.
38. Patte, C., and P. R. Blanquet. Possible involvement of arachidonic acid metabolites in the synergistic action of endothelial mitogenesis by fibroblast growth factor and phorbol ester. Cell. Mol. Biol. 38: 429-436, 1992.
39. Rothermel, J. D., B. Jastorff, and L. H. Bothelo. Inhibition of glucagon-induced glyco-genolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3′,5′-phosphorothioate. J. Biol. Chem. 259: 8151-8155, 1984.
40. Rozengurt, E. Early signals in the mitogenic response. Science 234: 161-166, 1986.
41. + exchanger NHE-1 by phosphorylating a set of common sites. J. Biol. Chem. 266: 19166-19171, 1991.
42. Teuscher, E., and V. Weidlich. Adenosine nucleotides, adenosine and adenine as angiogenesis factors. Biomed. Biochim. Acta 44: 493-495, 1985.
43. Van Daele, P., A. Van Coevorden, P. P. Roger, and J.-M. Boeynaems. Effects of adenine nucleotides on the proliferation of aortic endothelial cells. Circ. Res. 70: 82-90, 1992.
44. Zar, J. H. Biostatistical Analysis. Englewood Cliffs, NJ: Prentice-Hall, 1984, p. 150-153.