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Volumn 91, Issue 2, 1997, Pages 314-321

Immune enhancing effects of dehydroepiandrosterone and dehydroepiandrosterone sulphate and the role of steroid sulphatase

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; PRASTERONE; PRASTERONE SULFATE; STERYL SULFATASE;

EID: 0030910632     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00254.x     Document Type: Article
Times cited : (47)

References (35)
  • 2
    • 0003551021 scopus 로고
    • Adrenal androgen metabolism
    • ed. L. N. Parker, Academic Press Inc., New York
    • PARKER L.N. (1989) Adrenal androgen metabolism. In: Adrenal Androgens in Clinical Medicine (ed. L. N. Parker), p. 3. Academic Press Inc., New York.
    • (1989) Adrenal Androgens in Clinical Medicine , pp. 3
    • Parker, L.N.1
  • 3
    • 0025079183 scopus 로고
    • Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in post-menopausal women: Evidence for a reduced 17,20-desmolase enzymatic activity
    • LIU C.H., LAUGHLIN G.A., FISCHER U.G. & YEN S.S.C. (1990) Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in post-menopausal women: evidence for a reduced 17,20-desmolase enzymatic activity. J Clin Endocrinol Metab 7, 900.
    • (1990) J Clin Endocrinol Metab , vol.7 , pp. 900
    • Liu, C.H.1    Laughlin, G.A.2    Fischer, U.G.3    Yen, S.S.C.4
  • 4
    • 84965028377 scopus 로고
    • Dehydroepiandrosterone and androsterone levels in human plasma, effect of age, sex: Day-to-day and diurnal variations
    • MIGEON C.J., KELLER A.R., LAWRENCE B. & SHEPARD T.H. (1957) Dehydroepiandrosterone and androsterone levels in human plasma, effect of age, sex: day-to-day and diurnal variations. J Clin Endocrinol Metab 17, 1051.
    • (1957) J Clin Endocrinol Metab , vol.17 , pp. 1051
    • Migeon, C.J.1    Keller, A.R.2    Lawrence, B.3    Shepard, T.H.4
  • 5
    • 0022350406 scopus 로고
    • Steroid sulfotransferases and steroid sulfate sulfatases: Characterisation and biological roles
    • HOBKIRK R. (1985) Steroid sulfotransferases and steroid sulfate sulfatases: characterisation and biological roles. Can J Biochem Cell Biol 63, 1127.
    • (1985) Can J Biochem Cell Biol , vol.63 , pp. 1127
    • Hobkirk, R.1
  • 6
    • 0000388518 scopus 로고
    • Inhibition of mammalian glucose-6-phosphate dehydrogenase by steroids
    • MARKS P.A. & BANKS J.A. (1960) Inhibition of mammalian glucose-6-phosphate dehydrogenase by steroids. Proc Natl Acad Sci USA 46, 447.
    • (1960) Proc Natl Acad Sci USA , vol.46 , pp. 447
    • Marks, P.A.1    Banks, J.A.2
  • 7
    • 0023741331 scopus 로고
    • Hormonal intervention: 'Buffer hormones' or 'State dependency'. The role of dehydroepiandrosterone (DHEA), thyroid hormones, estrogen and hypophysectomy in aging
    • REGELSON W., LORIA R. & KALIMI M. (1988) Hormonal intervention: 'Buffer hormones' or 'State dependency'. The role of dehydroepiandrosterone (DHEA), thyroid hormones, estrogen and hypophysectomy in aging. Ann NY Acad Sci 521, 260.
    • (1988) Ann NY Acad Sci , vol.521 , pp. 260
    • Regelson, W.1    Loria, R.2    Kalimi, M.3
  • 8
    • 0019942001 scopus 로고
    • Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice
    • COLEMAN D.L., LEITER E.H. & SCHWIZER R.W. (1982) Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice. Diabetes 31, 830.
    • (1982) Diabetes , vol.31 , pp. 830
    • Coleman, D.L.1    Leiter, E.H.2    Schwizer, R.W.3
  • 9
    • 0010552302 scopus 로고
    • Dehydroepiandrosterone (DHEA) and diabetic syndromes in mice
    • eds M. Kalimi & W. Regelson, Walter de Gruyter and Co., Berlin
    • COLEMAN D.L. (1990) Dehydroepiandrosterone (DHEA) and diabetic syndromes in mice. In: The Biologic Role of Dehydroepiandrosterone (DHEA) (eds M. Kalimi & W. Regelson), p. 179. Walter de Gruyter and Co., Berlin.
    • (1990) The Biologic Role of Dehydroepiandrosterone (DHEA) , pp. 179
    • Coleman, D.L.1
  • 10
    • 0025959199 scopus 로고
    • The antiobesity effect of dehydroepiandrosterone in rats
    • CLEARY M.P. (1990). The antiobesity effect of dehydroepiandrosterone in rats. Proc Soc Exp Biol Med 196, 8.
    • (1990) Proc Soc Exp Biol Med , vol.196 , pp. 8
    • Cleary, M.P.1
  • 11
    • 0021025370 scopus 로고
    • Androgen and precursor levels in serum and testes of adult rats under basal conditions and after hCG stimulation
    • PUNJABI U., DESLYPERE J.P., VERDONCK L. & VERMEULEN A. (1983) Androgen and precursor levels in serum and testes of adult rats under basal conditions and after hCG stimulation. J Steroid Biochem 19, 1481.
    • (1983) J Steroid Biochem , vol.19 , pp. 1481
    • Punjabi, U.1    Deslypere, J.P.2    Verdonck, L.3    Vermeulen, A.4
  • 12
    • 0021278928 scopus 로고
    • Serum levels of testosterone precursors, testosterone and estradiol in 10 animals
    • WICHMANN U., WICHMANN G. & KRAUSE W. (1984) Serum levels of testosterone precursors, testosterone and estradiol in 10 animals. Exp Clin Endocrinol 83, 283.
    • (1984) Exp Clin Endocrinol , vol.83 , pp. 283
    • Wichmann, U.1    Wichmann, G.2    Krause, W.3
  • 13
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • ORENTREICH N., BRIND J.L., RIZER R.L. & VOGELMAN J.N. (1984) Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 59, 551.
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.N.4
  • 14
    • 0025284590 scopus 로고
    • Regulation of murine lymphokine production in vivo II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells
    • DAYNES R.A., DUDLEY D.J. & ARANEO B.A. (1990) Regulation of murine lymphokine production in vivo II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells. Eur J Immunol 20, 793.
    • (1990) Eur J Immunol , vol.20 , pp. 793
    • Daynes, R.A.1    Dudley, D.J.2    Araneo, B.A.3
  • 15
    • 0024802919 scopus 로고
    • Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4
    • DAYNES R.A. & ARANEO B.A. (1989) Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4. Eur J Immunol 19, 2319.
    • (1989) Eur J Immunol , vol.19 , pp. 2319
    • Daynes, R.A.1    Araneo, B.A.2
  • 16
    • 0025318862 scopus 로고
    • Regulation of murine lymphokine production in vivo III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function
    • DAYNES R.A., ARANEO B.A., DOWELL T.A., HUANG K. & DUDLEY D.J. (1990) Regulation of murine lymphokine production in vivo III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J Exp Med 171, 979.
    • (1990) J Exp Med , vol.171 , pp. 979
    • Daynes, R.A.1    Araneo, B.A.2    Dowell, T.A.3    Huang, K.4    Dudley, D.J.5
  • 17
    • 0026091953 scopus 로고
    • Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells
    • SUZUKI T., SUZUKI N., DAYNES R.A. & ENGLEMAN E.G. (1991) Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells. Clin Immunol Immunopathol 61, 202.
    • (1991) Clin Immunol Immunopathol , vol.61 , pp. 202
    • Suzuki, T.1    Suzuki, N.2    Daynes, R.A.3    Engleman, E.G.4
  • 18
    • 0025746332 scopus 로고
    • Dehydroepiandrosterone antagonises the suppressive effects of dexamethasone on lymphocyte proliferation
    • BLAUER K.L., POTH M., ROGER W.M. & BERNTON E.W. (1991) Dehydroepiandrosterone antagonises the suppressive effects of dexamethasone on lymphocyte proliferation. Endocrinology 129, 3174.
    • (1991) Endocrinology , vol.129 , pp. 3174
    • Blauer, K.L.1    Poth, M.2    Roger, W.M.3    Bernton, E.W.4
  • 19
    • 0028141375 scopus 로고
    • In vitro potentiation of lymphocyte activation by dehydroepiandrosterone, androstenediol, and androstenetriol
    • PADGETT D.A. & LORIA R.M. (1994) In vitro potentiation of lymphocyte activation by dehydroepiandrosterone, androstenediol, and androstenetriol. J Immunol 153, 1544.
    • (1994) J Immunol , vol.153 , pp. 1544
    • Padgett, D.A.1    Loria, R.M.2
  • 20
    • 0028206488 scopus 로고
    • Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in mice
    • MORFIN R. & COURCHAY G. (1994) Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in mice. J Steroid Biochem Molec Biol 50, 91.
    • (1994) J Steroid Biochem Molec Biol , vol.50 , pp. 91
    • Morfin, R.1    Courchay, G.2
  • 21
    • 0028009821 scopus 로고
    • Estrone Sulfamates: Potent inhibitors of estrone sulfatase with therapeutic potential
    • HOWARTH N.M., PUROHIT A., REED M.J. & POTTER B.V.L. (1994) Estrone Sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential. J Med Chem 37, 219.
    • (1994) J Med Chem , vol.37 , pp. 219
    • Howarth, N.M.1    Purohit, A.2    Reed, M.J.3    Potter, B.V.L.4
  • 22
    • 0029114308 scopus 로고
    • Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-sulfamate
    • PUROHIT A., WILLIAMS G.J., HOWARTH N.M., POTTER N.V.L. & REED M.J. (1995) Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-sulfamate. Biochemistry 34, 11 508.
    • (1995) Biochemistry , vol.34 , pp. 11508
    • Purohit, A.1    Williams, G.J.2    Howarth, N.M.3    Potter, N.V.L.4    Reed, M.J.5
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • BRADFORD M.M. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248.
    • (1976) Anal Biochem , vol.72 , pp. 248
    • Bradford, M.M.1
  • 24
    • 0000023950 scopus 로고
    • Uber das hydrazidosulphamid
    • APPEL R. & BERGER G. (1958) Uber das hydrazidosulphamid. Chem Ber 19, 1339.
    • (1958) Chem Ber , vol.19 , pp. 1339
    • Appel, R.1    Berger, G.2
  • 26
    • 0026624725 scopus 로고
    • The presence of a dehydroepiandrosterone-specific receptor binding complex in murine T cells
    • MEIKLE A.W., DORCHUCK R.W., ARANEO B.A. et al. (1992) The presence of a dehydroepiandrosterone-specific receptor binding complex in murine T cells. J Steroid Biochem Mol Biol 42, 293.
    • (1992) J Steroid Biochem Mol Biol , vol.42 , pp. 293
    • Meikle, A.W.1    Dorchuck, R.W.2    Araneo, B.A.3
  • 27
    • 0030067298 scopus 로고    scopus 로고
    • Dehydroepiandrosterone modulation of lipopolysaccharide-stimulated monocyte cytotoxicity
    • MCLACHLAN J.A., SERKIN C.D. & BAKOUCHE O. (1996) Dehydroepiandrosterone modulation of lipopolysaccharide-stimulated monocyte cytotoxicity. J Immunol 156, 328.
    • (1996) J Immunol , vol.156 , pp. 328
    • Mclachlan, J.A.1    Serkin, C.D.2    Bakouche, O.3
  • 28
    • 0028048169 scopus 로고
    • Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance
    • ROOK G.A.W., HERNANDEZ-PANDO R. & LIGHTMAN S.L. (1994) Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance. Immunol Today 15, 301.
    • (1994) Immunol Today , vol.15 , pp. 301
    • Rook, G.A.W.1    Hernandez-Pando, R.2    Lightman, S.L.3
  • 29
    • 0028962459 scopus 로고
    • Low serum levels of dehydroepiandrosterone may cause deficient IL-2 production by lymphocytes in patients with systemic lupus erythematosus (SLE)
    • SUZUKI T., SUZUKI N., ENGLEMAN E.G., MIZUSHIMA Y. & SAKANE T. (1995) Low serum levels of dehydroepiandrosterone may cause deficient IL-2 production by lymphocytes in patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 99, 251.
    • (1995) Clin Exp Immunol , vol.99 , pp. 251
    • Suzuki, T.1    Suzuki, N.2    Engleman, E.G.3    Mizushima, Y.4    Sakane, T.5
  • 31
    • 0026716183 scopus 로고
    • Dehydroepiandrosterone: Antiglucocorticoid action in mice
    • BROWNE E.S., WRIGHT B.E., PORTER J.R. & SVEC F. (1992) Dehydroepiandrosterone: antiglucocorticoid action in mice. Am J Med Sci 303, 366.
    • (1992) Am J Med Sci , vol.303 , pp. 366
    • Browne, E.S.1    Wright, B.E.2    Porter, J.R.3    Svec, F.4
  • 32
    • 0028985525 scopus 로고
    • Dehydroepiandrosterone functions as more than an anti-glucocorticoid in preserving immunocompetence after thermal injury
    • ARANEO B. & DAYNES R. (1995) Dehydroepiandrosterone functions as more than an anti-glucocorticoid in preserving immunocompetence after thermal injury. Endocrinology 136, 393.
    • (1995) Endocrinology , vol.136 , pp. 393
    • Araneo, B.1    Daynes, R.2
  • 33
    • 0028302689 scopus 로고
    • Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines
    • HENNEBOLD J.D. & DAYNES R.A. (1994) Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines. Endocrinology 135, 67.
    • (1994) Endocrinology , vol.135 , pp. 67
    • Hennebold, J.D.1    Daynes, R.A.2
  • 34
  • 35
    • 8244247830 scopus 로고
    • The molecular basis of T cell responses
    • eds JM Austyn and KJ Wood, Oxford University Press, New York
    • AUSTYN J.M. & WOOD K.J. (1993) The molecular basis of T cell responses. In: Principles of Cellular and Molecular Immunology (eds JM Austyn and KJ Wood), p. 181. Oxford University Press, New York.
    • (1993) Principles of Cellular and Molecular Immunology , pp. 181
    • Austyn, J.M.1    Wood, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.