Mediators and mechanisms associated with paroxysm in Plasmodium vivax malaria

Journal of Pharmacy and Pharmacology

Volumn 49, Issue SUPPL. 2, 1997, Pages 35-41

  Carter, R ^a   Wijesekera, S K ^b   Karunaweera, N D ^b   Mendis, K N ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF COLOMBO   (Sri Lanka)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL FEATURE; MALARIA; MEDIATOR; PLASMODIUM VIVAX; SYMPTOM;

EID: 0030910497     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06158.x     Document Type: Article

References (21)

1. Allan, R. J., Rowe, A., Kwiatkowski, D. (1993) Plasmodium falciparum varies in its ability to induce tumour necrosis factor. Infect. Immun. 61: 4772-4776
2. Bate, C. A. W., Taverne, J., Karunaweera, N. D., Mendis, K. N., Kwiatkowski, D., Playfair, J. H. L. (1992) Serological relationship of tumour necrosis factor-inducing exoantigens of Plasmodium falciparum and Plasmodium vivax. Infect. Immun. 60: 1241-1243
3. Clark, I. A., Rockett, K. A., Cowden, W. B. (1992) TNF in malaria. In: Beutler, B. (ed.) Tumour Necrosis Factor: The Molecules and Their Emerging Role in Medicine. Raven Press, New York, p. 303
4. Currier, J., Beck, H. P., Currie, B., Good, M. F. (1995) Antigens released at schizont burst stimulate Plasmodium falciparum - specific CD4(+) T-cells from non-exposed donors - potential for cross-reactive memory T-cells to cause disease. Int. Immunol. 7: 821-833
5. Dick, S., Waterfall, M., Currie, J., Maddy, A., Riley, E. (1996) Naive human αβT cells respond to membrane-associated components of malaria-infected erythrocytes by proliferation and production of interferon-γ. Immunol. 88: 412-420
6. Grau, G. E., Taylor, T. E., Molineux, M. E., Wirima, J. T., Vasselli, P., Hommel, M., Lambert, P. H. (1989) Tumour necrosis factor and disease severity in children with falciparum malaria. N. Engl. J. Med. 320: 1586-1591
7. Jones, K. R., Hickling, J. K., Targett, G. A. T., Playfair, J. H. L. (1990) Polyclonal in vitro proliferative responses from non-immune donors to Plasmodium falciparum malaria antigens require UCHL1+ (memory) T cells. Eur. J. Immunol. 20: 307-310
8. Karunaweera, N. D., Carter, R., Grau, G. E., Kwiatkowski, D., Del Giudice, G., Mendis, K. N. (1992a) Tumour necrosis factor-dependent parasite-killing effects during paroxysms in non-immune Plasmodium vivax malaria patients. Clin. Exp. Immunol. 88: 499-505
9. Karunaweera, N. D., Grau, G. E., Gamage, P., Carter, R., Mendis, K. N. (1992b) Dynamics of fever and serum TNF levels are closely associated during clinical paroxysms in Plasmodium vivax malaria. Proc. Natl Acad. Sci. USA 89: 3200-3203
10. Kern, P., Hemmer, C. J., Vandamme, J., Gruss, H. J., Dietrich, M. (1989) Elevated tumour necrosis factor-alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. Am. J. Med. 87: 139-143
11. Kwiatkowski, D. (1989) Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro. J. Exp. Med. 169: 357-361
12. Kwiatkowski, D. (1995) Malaria toxins and the regulation of parasite density. Parasitol. Today 11: 206-212
13. Kwiatkowski, D., Cannon, J. G., Manogue, K. R., Cerami, A., Dinarello, C. A., Greenwood, B. M. (1989) Tumour necrosis factor production in falciparum-malaria and its association with schizont rupture. Clin. Exp. Immunol. 77: 361-366
14. Kwiatkowski, D., Hill, A. V. S., Sambou, I., Twumasi, P., Castracane, J., Manogue, K. R., Cerami, A., Brewster, D. R., Greenwood, B. M. (1990) TNF concentrations in fatal cerebral, nonfatal cerebral, and uncomplicated Plasmodium-falciparum malaria. Lancet 336: 1201-1204
15. Kwiatkowski, D., Molineux, M. E., Stephens, S., Curtis, N., Klein, N., Pointaire, P., Smit, M., Allan, R., Brewster, D. R., Grau, G. E., Greenwood, B. M. (1993) Anti-TNF therapy inhibits fever in cerebral malaria. Quart. J. Med. 86: 91-98
16. Mendis, K. N., Carter, R. (1995) Clinical Disease and Pathogenesis in Malaria. Parasitol. Today 11: 1-16
17. Mier, J. W., Vachino, G., Van Der Meer, J. W. M., Numerof, R. P, Adams, A., Cannon, J. G., Bernheim, H. A., Atkins, M. B., Parkinson, D. R., Dinarello, C. A. (1988) Induction of circulating tumour necrosis factor (TNFα) as the mechanism for the febrile response to Interleukin-2 (IL-2) in cancer patients. J. Clin. Immunol. 8: 426-436
18. Naotunne, T. de S., Karunaweera, N. D., Mendis, K. N., Carter, R. (1993) Cytokine-mediated inactivation of malarial gametocytes is dependent on the presence of white blood cells and involves reactive nitrogen intermediates. Immunol. 78: 555-562
19. Playfair, J. H. L., Taverne, J., Bate, C. A. W., DeSouza, J. B. (1990) The malaria vaccine - antiparasitic or antidisease. Immunol. Today 11: 25-27
20. Rosenau, M. J., Parker, H. B., Francis, E., Beyer, G. E. (1905) Report of Working Party No. 2, Yellow Fever Institute. Experimental studies in Yellow Fever and Malaria at Vera Cruz, Mexico, Yellow Fever Institute, Bulletin No. 14, Washington Government Printing Office, pp 49-101
21. Wijesekera, S. K., Carter, R. Rathnayaka, L., Mendis, K. N. (1996) A malaria parasite toxin associated with Plasmodium vivax paroxysms. Clin. Exp. Immunol. 104: 221-227