Use of the intestinal bile acid transporter for the uptake of cholic acid conjugates with HIV-1-protease inhibitory activity

Pharmaceutical Research

Volumn 14, Issue 2, 1997, Pages 176-180

  Kågedahl, Matts ^a   Swaan, Peter W ^a   Redemann, Carl T ^a   Tang, Mary ^a   Craik, Charles S ^a   Szoka Jr , Francis C ^a   Øie, Svein ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

AIDS; Bile acid carrier; Drug conjugates; HIV protease inhibition; Intestinal transport

Indexed keywords

BILE ACID CONJUGATE; CARRIER PROTEIN; TAUROCHOLIC ACID;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; INTESTINE ABSORPTION; ISOTOPE LABELING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEINASE INHIBITION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CARRIER PROTEINS; CHOLIC ACIDS; EPITHELIUM; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; HYDROXYSTEROID DEHYDROGENASES; MEMBRANE GLYCOPROTEINS; SODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TAUROCHOLIC ACID;

EID: 0030910379     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012044526054     Document Type: Article

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