Calreticulin biosynthesis and processing in human myeloid cells: Demonstration of signal peptide cleavage and N-glycosylation

Blood

Volumn 90, Issue 1, 1997, Pages 372-381

  Denning, Gerene M ^b   Leidal, Kevin G ^b   Holst, Valerie A ^b   Iyer, Shankar S ^b   Pearson, Doran W ^b   Clark, Joshua R ^b   Nauseef, William M ^b   Clark, Robert A ^a  

^a Univ of Texas Health Science Center ^*  (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN;

ARTICLE; BONE MARROW CELL; CELL STRAIN HL 60; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

EID: 0030910249     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.1.372.372_372_381     Document Type: Article

References (49)

1. Michalak M, Milner RE, Burns K, Opas M: Calreticulin. Biochem J 285:681, 1992
2. Van Delden C, Favre C, Spät A, Cerny E, Krause K-H, Lew DP: Purification of an inositol 1,4,5-trisphosphate-binding calreticulin-containing intracellular compartment of HL-60 cells. Biochem J 281:651, 1992
3. 2+ binding to control of gene expression. Trends Cell Biol 4:152, 1994
4. Nash PD, Opas M, Michalak M: Calreticulin: Not just another calcium-binding protein. Mol Cell Biochem 135:71, 1994
5. Khanna NC, Waisman DM: Development of a radioimmunoassay for quantitation of calregulin in bovine tissues. Biochemistry 25:1078, 1986
6. Fliegel L, Burns K, MacLennan DH, Reithmeier RAF, Michalak M: Molecular cloning of the high affinity calcium-binding protein (calreticulin) or skeletal muscle sarcoplasmic reliculum. J Biol Chem 264:21522, 1989
7. McCauliffe DP, Zappi E, Lieu T-S, Michalak M, Sontheimer RD, Capra JD: A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia "memory molecule". J Clin Invest 86:332, 1990
8. 2+ binding domains. J Biol Chem 266:21458, 1991
9. Dedhar S: Novel functions for calreticulin: Interaction with integrins and modulation of gene expression. Trends Biochem Sci 19:269, 1994
10. Sontheimer RD, Nguyen TQ, Cheng ST, Lieu TS, Capra JD: The unveiling of calreticulin - A clinically relevant tour of modern cell biology. J Invest Med 43:362, 1995
11. Meldolesi J, Krause KH, Michalak M: Calreticulin: How many functions in how many cellular compartments. Cell Calcium 20:83, 1996
12. Rojiani MV, Finlay BB, Gray V, Dedhar S: In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin a subunits. Biochemistry 30:9859, 1991
13. Leung-Hagesteijn CY, Milankov K, Michalak M, Wilkins J, Dedhar S: Cell attachment to extracellular matrix substrates is inhibited upon downregulation of expression of calreticulin, an intracellular integrin α-subunit-binding protein. J Cell Sci 107:589, 1994
14. Dedhar S, Rennie PS, Shago M, Leung Hagesteijn C-Y, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ, Giguère V: Inhibition of nuclear hormone receptor activity by calreticulin. Nature 367:480, 1994
15. Burns K, Duggan B, Atkinson EA, Famulski KS, Nemer M, Bleackley RC, Michalak M: Modulation of gene expression by calreticulin binding to the glucocorticoid receptor. Nature 367:476, 1994
16. Dupuis M, Schaerer E, Krause K-H, Tschopp J: The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes. J Exp Med 177:1, 1993
17. McCauliffe DP, Lux FA, Lieu T-S, Sanz I, Hanke J, Newkirk MM, Bachinski LL, Itoh Y, Siciliano MJ, Reichlin M, Sontheimer RD, Capra JD: Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen. J Clin Invest 85:1379, 1990
18. Rokeach LA, Haselby JA, Meilof JF, Smeenk RJT, Unnasch TR, Greene BM, Hoch SO: Characterization of the autoantigen calreticulin. J Immunol 147:3031, 1991
19. Karská K, Tucková L, Steiner L, Tlaskalová-Hogenová H, Michalak M: Calreticulin - The potential autoantigen in celiac disease. Biochem Biophys Res Commun 209:597, 1995
20. Cheng ST, Nguyen TQ, Yang YS, Capra JD, Sontheimer RD: Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen. J Immunol 156:4484, 1996
21. Singh NK, Atreya CD, Nakhasi HL: Identification of calreticulin as a rubella virus RNA binding protein. Proc Natl Acad Sci USA 91:12770, 1994
22. Atreya CD, Singh NK, Nakhasi HL: The rubella virus RNA binding activity of human calreticulin is localized to the N-terminal domain. J Virol 69:3848, 1995
23. White TK, Zhu Q, Tanzer ML: Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading. J Biol Chem 270:15926, 1995
24. Kuwabara K, Pinsky DJ, Schmidt AM, Benedict C, Brett J, Ogawa S, Broekman MJ, Marcus AJ, Sciacca RR, Michalak M, Wang F, Pan YC, Grunfeld S, Patton S, Malinski T, Stern DM, Ryan J: Calreticulin, an antithrombotic agent which binds to vitamin K-dependent coagulation factors, stimulates endothelial nitric oxide production, and limits thrombosis in canine coronary arteries. J Biol Chem 270:8179, 1995
25. Nauseef WM, McCormick SJ, Clark RA: Calreticulin functions as a molecular chaperone in the biosynthesis of myeloperoxidase. J Biol Chem 270:4741, 1995
26. Peterson JR, Ora A, Van PN, Helenius A: Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins. Mol Biol Cell 6:1173, 1995
27. Smith MJ, Koch GLE: Multiple zones in the sequence of calreticulin (CRP55, calregulin, HACBP), a major calcium binding ER/SR protein. EMBO J 8:3581, 1989
28. Murthy KK, Banville D, Srikant CB, Carrier F, Holmes C, Bell A, Patel YC: Structural homology between the rat calreticulin gene product and the Onchocerca volvulus antigen Ral-1. Nucleic Acids Res 18:4933, 1990
29. Volpp BD, Nauseef WM, Donelson JE, Moser DR, Clark RA: Cloning of the cDNA and functional expression of the 47 kilodalton cytosolic component of the human neutrophil respiratory burst oxidase. Proc Natl Acad Sci USA 86:7195, 1989
30. Matsuoka K, Seta K, Yamakawa Y, Okuyama T, Shinoda T, Isobe T: Covalent structure of bovine brain calreticulin. Biochem J 298:435, 1994
31. Milner RE, Baksh S, Shemanko C, Carpenter MR, Smillie L, Vance JE, Opas M, Michalak M: Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum. J Biol Chem 266:7155, 1991
32. 2+ store in HL-60 cells. Biochem J 270:545, 1990
33. Campbell KP, MacLennan DH, Jorgensen AO: Staining of the Ca2+-binding proteins, calsequestrin, calmodulin, troponin C, and S-100, with the cationic carbocyanine dye "stains-all". J Biol Chem 258:11267, 1983
34. Borregaard N, Heiple JM, Simons ER, Clark RA: Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase. Translocation during activation. J Cell Biol 97:52, 1983
35. Collins SJ, Gallo RC, Gallagher RE: Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature 270:347, 1977
36. Tucker KA, Lilly MB, Heck L Jr, Rado TA: Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood 70:372, 1987
37. Nauseef WM: Myeloperoxidase biosynthesis by a human promyelocytic leukemia cell line: Insight into myeloperoxidase deficiency. Blood 67:865, 1986
38. Johnson KR, Nauseef WM: Molecular biology of MPO, in Everse J, Everse KE, Grisham MB (eds): Peroxidases in Chemistry and Biology, Boca Raton, FL, CRC, 1991, p 63
39. Nakayasu M, Terada M, Tamura G, Sugimura T: Induction of differentiation of human and murine myeloid leukemia cells in culture by tunicamycin. Proc Natl Acad Sci USA 77:409, 1980
40. Nauseef WM: Posttranslational processing of a human myeloid lysosomal protein, myeloperoxidase. Blood 70:1143, 1987
41. Peter F, Van PN, Söling H-D: Different sorting of Lys-AspGlu-Leu proteins in rat liver. J Biol Chem 267:10631, 1992
42. Khanna NC, Tokuda M, Waisman DM: Comparison of calregulins from vertebrate livers. Biochem J 242:245, 1987
43. Michalak M, MacLennan DH: Assembly of the sarcoplasmic reticulum: Biosynthesis of the high affinity calcium binding protein in rat skeletal muscle cell cultures. J Biol Chem 255:1327, 1980
44. Michalak M, Campbell KP, MacLennan DH: Localization of the high affinity calcium binding protein and an intrinsic glycoprotein in sarcoplasmic reticulum membranes. J Biol Chem 255:1317, 1980
45. Lewis MJ, Turco SJ, Green M: Structure and assembly of the endoplasmic reticulum. Biosynthetic sorting of endoplasmic reticulum proteins. J Biol Chem 260:6926, 1985
46. Lewis MJ, Mazzarella RA, Green M: Structure and assembly of the endoplasmic reticulum: The synthesis of three major endoplasmic reticulum proteins during lipopolysaccharide-induced differentiation of murine lymphocytes. J Biol Chem 260:3050, 1985
47. Lewis MJ, Mazzarella RA, Green M: Structure and assembly of the endoplasmic reticulum: Biosynthesis and intracellular sorting of ERp61, ERp59, and ERp49, three protein components of murine endoplasmic reticulum. Arch Biochem Biophys 245:389, 1986
48. Van PN, Peter F, Soling H-D: Four intracisternal calcium-binding glycoproteins from rat liver microsomes with high affinity for calcium: No indication for calsequestrin-like proteins in inositol 1,4,5-trisphosphate-sensitive calcium sequestering rat liver vesicles. J Biol Chem 264:17494, 1989
49. Jethmalani SM, Henle KJ, Kaushal GP: Heat shock-induced prompt glycosylation. Identification of P-SG67 as calreticulin. J Biol Chem 269:23603, 1994